Modulation of leukocyte-endothelium interaction by nitric oxide synthase inhibitors: Effects on leukocyte adhesion in endotoxin-induced uveitis

Inflammation Research

Volumn 50, Issue 11, 2001, Pages 534-543

  Baatz, H ^a   Pleyer, U ^b  

^a GOETHE UNIVERSITY   (Germany)

^b HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Aminoguanidine; Endotoxin induced uveitis; Intravital microscopy; Leukocyte endothelium interaction; Nitric oxide

Indexed keywords

AMINOGUANIDINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL EXPERIMENT; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; DRUG EFFECT; ENZYME REGULATION; FEMALE; IMMUNOMODULATION; LEUKOCYTE ADHERENCE; NONHUMAN; RAT; UVEITIS; VASCULAR ENDOTHELIUM;

EID: 0035213286     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000231     Document Type: Article

References (43)

1. Endotoxin-induced uveitis in the rat: Observations on altered vascular permeability, clinical findings, and histology
2. The microcirculation and inflammation: Modulation of leukocyte-endothelial cell adhesion
3. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
4. Monoclonal antibodies against ICAM-1 (CD54) and LFA-1 (CD11a/CD18) inhibit experimental autoimmune uveitis
5. Monoclonal antibody against CD11b/CD18 inhibits endotoxin-induced uveitis
6. Monoclonal antibodies against CD54 (ICAM-1) and CD11a (LFA-1) prevent and inhibit endotoxin-induced uveitis
7. Nitric oxide: An endogenous modulator of leukocyte adhesion
8. Endogenous but not exogenous nitric oxide decreases TNF-alpha-induced leukocyte rolling
9. Expression of inducible nitric oxide synthase in the eye from endotoxin-induced uveitis rats
10. The role of nitric oxide synthase in endotoxin-induced uveitis: Effects of NG-nitro L-arginine
11. Endotoxin-induced uveitis in the rat is attenuated by inhibition of nitric oxide production
12. Increased nitric oxide production in endotoxin-induced uveitis. Reduction of uveitis by an inhibitor of nitric oxide synthase
13. The role of nitric oxide in uveitis
14. In vivo study of leukocyte-endothelium interaction in endotoxin-induced uveitis
15. Kinetics of white blood cell staining by intravascular administration of rhodamine 6G
16. Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice
17. Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase
18. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis
19. Inhibition of nitric oxide synthase attenuates blood-brain barrier disruption during experimental meningitis
20. Effects of nitric oxide synthase inhibition on the pathophysiology observed in a model of chronic granulomatous colitis
21. Studies on the mechanisms involved in the inflammatory response in a reversed passive Arthus reaction in guinea-pig skin: Contribution of neutrophils and endogenous mediators
22. Role of nitric oxide in a nonseptic shock model induced by zymosan in the rat
23. Suppression of adjuvant-induced arthritis by selective inhibition of inducible nitric oxide synthase
24. Therapeutic administration of a selective inhibitor of nitric oxide synthase does not ameliorate the chronic inflammation and tissue damage associated with adjuvant-induced arthritis in rats
25. Modulation of adjuvant arthritis by endogenous nitric oxide
26. Nitric oxide synthase inhibitors exert differential time-dependent effects on LPS-induced uveitis
27. Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism
28. Aminoguanidine-provoked leukocyte adherence to rat mesenteric venules: Role of constitutive nitric oxide synthase inhibition
29. Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation
30. Rapid leukocyte accumulation by "spontaneous" rolling and adhesion in the exteriorized rabbit mesentery
31. Regulation of P-selectin expression in human endothelial cells by nitric oxide
32. L-N6-(1-iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo
33. Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo
34. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine
35. Time-dependent actions of nitric oxide synthase inhibition on colonic inflammation induced by trinitrobenzene sulphonic acid in rats
36. Time-dependent enhancement or inhibition of endotoxin-induced vascular injury in rat intestine by nitric oxide synthase inhibitors
37. Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils
38. Local L-NAME decreases blood flow and increases leukocyte adhesion via CD18
39. The inhibitory effects of mercaptoalkylguanidines on cyclo-oxygenase activity
40. Peroxynitrite and oxidative damage in experimental autoimmune uveitis
41. Nitric oxide prevents leukocyte adherence: Role of superoxide
42. A balance between nitric oxide and oxidants regulates mast cell-dependent neutrophil-endothelial cell interactions
43. Exogenous NO enhances hydrogen peroxide-mediated neutrophil adherence to cultured endothelial cells