Chronic benzodiazepine treatment of cells expressing recombinant GABAA receptors uncouples allosteric binding: Studies on possible mechanisms

Journal of Neurochemistry

Volumn 79, Issue 5, 2001, Pages 1100-1108

  Ali, Noore J ^a   Olsen, Richard W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Benzodiazepine; GABAA receptor; Internalization; Phosphorylation; Uncoupling

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; BENZODIAZEPINE; FLUMAZENIL; PROTEIN KINASE C; UNCOUPLING PROTEIN;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CELL MEMBRANE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG TOLERANCE; ELECTROPHYSIOLOGY; IMMUNOCYTOCHEMISTRY; INTERNALIZATION; NONHUMAN; OSMOTIC STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; BENZODIAZEPINES; CELL LINE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DRUG TOLERANCE; HYDROGEN-ION CONCENTRATION; IMMUNOHISTOCHEMISTRY; INSECTS; OSMOTIC PRESSURE; PHOSPHORYLATION; PROTEIN KINASE C; RADIOLIGAND ASSAY; RATS; RECEPTORS, GABA-A; RECOMBINANT PROTEINS; TRANSFECTION;

ANIMALIA;

EID: 0035212788     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2001.00664.x     Document Type: Article

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