Cell biology of tissue factor, an unusual member of the cytokine receptor family

Trends in Cardiovascular Medicine

Volumn 11, Issue 8, 2001, Pages 335-339

  Peppelenbosch, Maikel P ^a   Versteeg, Henri H ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; BLOOD CLOTTING FACTOR 7A; CYTOKINE RECEPTOR; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN CDC42; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 1; RAC PROTEIN; RHO FACTOR; THROMBIN INHIBITOR; THROMBOPLASTIN;

BLOOD CLOTTING; CARCINOGENESIS; CELL SPREADING; CELL SURVIVAL; CHEMOKINESIS; CHEMOTAXIS; CYTOLOGY; GENETIC TRANSCRIPTION; INFLAMMATION; LAMELLIPODIUM; NONHUMAN; ONCOGENE SRC; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SYNTHESIS; REGULATORY MECHANISM; SHORT SURVEY; SIGNAL TRANSDUCTION;

EID: 0035204054     PISSN: 10501738     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1050-1738(01)00137-2     Document Type: Review

References (33)

1. Structural design and molecular evolution of a cytokine receptor superfamily
2. Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation
3. Cell biology of tissue factor, the principal initiator of blood coagulation
4. Coagulation factors VII and X induce Ca2+ oscillations in Madin-Darby Canine Kidney cells only when proteolytically active
5. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa
6. Role of tissue factor in embryonic blood vessel development
7. Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock
8. Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages
9. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase
10. Crystal structure of the extracellular region of human tissue factor
11. Tumour infarction in mice by antibody-directed targeting of tissue factor to tumour vasculature
12. Molecular cloning of the cDNA for tissue factor, the cellular receptor for the initiation of the protease cascade
13. Requirement for binding of catalytically active factor VIIa in tissue factor dependent experimental metastasis
14. Structure of the extracellular domain of human tissue factor: Location of the factor VIIa binding site
15. A role for tissue factor in cell adhesion and migration mediated by interaction with actin-binding protein 280
16. Binding of factor VIIa to tissue factor induces alterations in gene expression in human fibroblast cells: Upregulation of poly(A) polymerase
17. Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, matrix signaling proteins that could act as possible downstream mediators in factorVIIa x tissue factor-induced signal transduction
18. 2+ influx
19. Exclusion of known protease-activated receptors in factor VIIa-induced signal transduction
20. Tissue factor-dependent factor VIIa signaling
21. Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor
22. Factor VIIa-induced gene expresion: Potential implications in pathophysiology
23. Role of tissue factor in adhesion of mononuclear phagocytes to and trafficking through endothelium in vitro
24. Rho family proteins and cell migration
25. 2+ signals in J82 cells, transfected Cos-1 cells, Madin Darby Canine Kidney cells and in human endothelial cells, induced to synthesize tissue factor
26. Factor VIIa-induced p44/42 mitogen-activated protein kinase activation requires the proteolytic activity of factor VIIa and is independent of the tissue factor cytoplasmic domain
27. Kit signaling through PI 3-kinase and Src kinase pathways: An essential role for Rac1 and JNK activation in mast cell proliferation
28. Targeted disruption of the murine tissue factor gene results ion embryonic lethality
29. Activation of RhoA by thrombin in endothelial hyperpermeability: Role of Rho kinase and protein tyrosine kinases
30. Factor VIIa/tissue factor-induced signaling via activation of Src-like kinases, phosphatidylinositol 3-kinase, and Rac
31. The role of phosphatidylinositide-3-kinase in basal mitogen-activated protein kinase activity and cell survival
32. Cellular effects of initiation of the extrinsic pathway of blood coagulation
33. Tissue factor controls the balance of angiogenic and antiangiogenic properties of tumour cells in mice