The nuclear envelope: Emerging roles in development and disease

Cellular and Molecular Life Sciences

Volumn 58, Issue 12-13, 2001, Pages 1737-1740

  Wolfner, M F ^a   Wilson, K L ^b  

^a Department of Obstetrics Gynecology   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Cell cycle; Development; Emery Dreifuss muscular dystrophy; Fertilization; Germ cells; Nuclear lamins; Nuclear membranes; Nuclear migration; Nuclear pore complexes; Nucleocytoplasmic transport; Plant nuclear envelope; Ran

Indexed keywords

EMERIN; LAMIN B; LAMINA ASSOCIATED POLYPEPTIDE 1; MEMBRANE PROTEIN; NUCLEAR PROTEIN; PROTEIN LEM; PROTEIN MAN1; UNCLASSIFIED DRUG;

APOPTOSIS; CELL DIVISION; CELL FATE; CELL MIGRATION; CELL NUCLEUS MEMBRANE; CELL POLARITY; CHROMATIN STRUCTURE; DEVELOPMENTAL BIOLOGY; DISEASE COURSE; DNA REPLICATION; FERTILIZATION; GAMETOGENESIS; GENE EXPRESSION; GENE MUTATION; GENE SILENCING; MOLECULAR DYNAMICS; PRONUCLEUS; REVIEW;

EUKARYOTA;

EID: 0035197366     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000812     Document Type: Review

References (34)

1. Inner nuclear membrane proteins: Functions and targeting
2. The structure and function of nuclear lamins: Implications for disease
3. Nuclear envelope and nuclear matrix: Interactions and dynamics
4. Gatekeepers of the nucleus
5. Nuclear pores and nuclear assembly
6. Nuclear transport mechanisms
7. Dynamics of the nuclear envelope at mitosis and during apoptosis
8. Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy
9. Lamins and disease: Insights into nuclear infrastructure
10. Identification of a novel X-linked gene responsible for Emery-Dreifuss muscular dystrophy
11. Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C
12. The nuclear envelope, muscular dystrophy and gene expression
13. Heart to heart: From nuclear proteins to Emery-Dreifuss muscular dystrophy
14. Lamins in disease: Why do ubiquitously expressed nuclear envelope proteins give rise to tissue-specific disease phenotypes?
15. Transcriptional repression, apoptosis, human disease and the functional evolution of the nuclear lamina
16. IV, a nuclear lamina protein specific for the male germ line
17. Expression of Drosophila lamin C is developmentally regulated: Analogies with vertebrate A-type lamins
18. Formation of the male pronuclear lamina in Drosophila
19. cDNA cloning of a germ cell specific lamin B3 from mouse spermatocytes and analysis of its function by ectopic expression in somatic cells
20. Transforming sperm nuclei into male pronuclei in vivo and in vitro
21. Movement of nuclei along microtubules in Xenopus egg extracts
22. Mechanisms of nuclear positioning
23. The Drosophila maternal effect gene fs(1)Ya encodes a cell cycle dependent nuclear envelope component required for embryonic mitosis
24. Mutational analyses of fs(1)Ya, a developmentally regulated nuclear envelope protein in Drosophila
25. The Drosophila embryonic nuclear lamina protein 'Young arrest' (fs(1)Ya) is capable of associating with chromatin
26. Interactions between Drosophila nuclear envelope proteins lamin, otefin and YA
27. The Ketel gene encodes a Drosophila homologue of importin-beta
28. The Ketel(D) dominant-negative mutations identify maternal function of the Drosophila importin-beta gene required for cleavage nuclei formation
29. Germ cell-less encodes a cell type-specific nuclear pore-associated protein and functions early in the germ-cell specification pathway of Drosophila
30. Germ cell-less is required only during the establishment of the germ cell lineage of Drosophila and has activities which are dependent and independent of its localization to the nuclear envelope
31. Nuclear membrane protein, LAP2β, mediates transcriptional repression alone and together with its binding partner GCL (germ cell-less)
32. UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development
33. A nuclear lamin required for cytoplasmic organization and egg polarity in Drosophila
34. The plant nuclear envelope