Soluble adhesion molecules in preclinical type 1 diabetes

Pediatric Research

Volumn 49, Issue 1, 2001, Pages 24-29

  Toivonen, A ^a   Kulmala, P ^a   Savola, K ^a   Akerblom H K ^a   Knip, M ^a   Tuomilehto, J ^a   Lounamaa, R ^a   Toivonen, L ^a   Virtala, E ^a   Pitkaniemi J ^a   Fagerlund, A ^a   Flittner, M ^a   Gustafsson, B ^a   Haggquist C ^a   Hakulinen, A ^a   Huupponen, T ^a   Joki, T ^a   Jokisalo, R ^a   Kaar M L ^a   Kallio, S ^a   Kaprio, E A ^a   Kaski, U ^a   Laine, L ^a   Lappalainen, J ^a   Maenpaa J ^a   Makela A L ^a   Niemi, K ^a   Niiranen, A ^a   Nuuja, A ^a   Ojajarvi P ^a   Otonkoski, T ^a   Pihlajamaki K ^a   Pontynen S ^a   Rajantie, J ^a   Sankala, J ^a   Schumacher, J ^a   Sillanpaa M ^a   Stahlberg M R ^a   Strahlmann C H ^a   Uotila, T ^a   Vare M ^a   Varimo, P ^a   Wetterstrand, G ^a   Aro, A ^a   Hiltunen, M ^a   Hurme, H ^a   Hyoty H ^a   Ilonen, J ^a   Karjaleinen, J ^a   Leinikki, P ^a   Miettinen, A ^a   Petays T ^a   Tuomilehto Wolf, E ^a   Vahasalo P ^a   Virtanen, S M ^a   more..

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CELL ADHESION MOLECULE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; PANCREAS ISLET CELL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE;

ADOLESCENT; ADULT; ANTIBODY DETECTION; ARTICLE; CHILD; DISEASE COURSE; DISEASE MARKER; GENETIC RISK; HIGH RISK PATIENT; HUMAN; INFANT; INSULIN RELEASE; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 0035196955     PISSN: 00313998     EISSN: None     Source Type: Journal    
DOI: 10.1203/00006450-200101000-00009     Document Type: Article

References (43)

1. In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
2. Insulitis in type 1 (insulin-dependent) diabetes mellitus in man-macrophages, lymphocytes, and interferon-gamma-containing cells
3. Adhesion receptors of the immune system
4. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
5. IFN-gamma enhances endothelial activation induced by tumor necrosis factor but not IL-1
6. T lymphocytes capable of activating endothelial cells in vitro are present in rats with autoimmune diabetes
7. Expression of a tumor necrosis factor-alfa transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes
8. Transgenic tumor necrosis factor (TNF)-alfa production in pancreatic islets leads to insulitis, not diabetes
9. Role of TNF-alfa in the development of autoimmunity and the pathogenesis of insulin-dependent diabetes mellitus in NOD mice
10. Effect of tumor necrosis factor-alfa on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and diabetogenic process
11. Mononuclear cell infiltration and its relation to the expression of major histocompatibility complex antigens and adhesion molecules in pancreas biopsy specimens from newly diagnosed insulin-dependent diabetes mellitus patients
12. Analysis of T cell stimulation by superantigen plus major histocompatibility complex class II molecules or by CD3 monoclonal antibody: Costimulation by purified adhesion ligands VCAM-1, ICAM-1, but not ELAM-1
13. Differential costimulatory effects of adhesion molecules B7, ICAM-1, LFA-3, and VCAM-1 on resting and antigen-primed CD+T lymphocytes
14. Expression of intercellular adhesion molecule 1 on pancreatic beta-cells accelerates beta-cell destruction by cytotoxic T-cells in murine autoimmune diabetes
15. Leukocyte-endothelial adhesion molecules
16. Traffic signals for lymphocyte recirculation and leukocyte emigration: The multistep paradigm
17. Elevated levels of circulating adhesion molecules in IDDM patients and in subjects at risk for IDDM
18. Differential patterns of circulating adhesion molecules in children with bronchial asthma and acute bronchiolitis
19. Soluble intercellular adhesion molecule-1 in paediatric connective tissue diseases
20. Soluble forms of intercellular adhesion molecule-1 in insulin-dependent diabetes mellitus
21. Soluble forms of intercellular adhesion molecule-1 inhibit insulitis and onset of autoimmune diabetes
22. Combined analysis of autoantibodies improves prediction of IDDM in islet cell autoantibody-positive relatives
23. Interactions of age, islet cell antibodies, insulin autoantibodies, and first-phase insulin response in predicting risk of progression to IDDM in ICA+ relatives: The ICARUS data set. Islet Cell Antibody Register Users Study
24. Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study
25. Epidemiology of childhood diabetes in Finland: Background of a nationwide study of type 1 (insulin-dependent) diabetes mellitus
26. Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies
27. Insulin antibodies in insulin-dependent diabetics before insulin treatment
28. Combined use of autoantibodies (IA-2 antoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop
29. Detection of GAD65 antibodies in diabetes and other autoimmune diseases using a simple radioligand assay
30. Glutamic acid decarboxylase antibodies in relation to other autoantibodies and genetic risk markers in children with newly diagnosed insulin-dependent diabetes
31. IA-2 antibodies-a sensitive marker of IDDM with clinical onset in childhood and adolescence
32. Coated charcoal immunoassay of insulin
33. Pre-type 1 diabetes: Linear loss of beta cell response to intravenous glucose
34. Enzymatic determination of hexoses in blood and urine
35. New susceptibility haplotype for type 1 diabetes
36. Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies
37. A form of circulating ICAM-I in human serum
38. Circulating adhesion molecules in disease
39. Increased level of circulating intercellular adhesion molecule 1 in Kawasaki disease
40. Soluble adhesion molecules and von Willebrand factor in children with Kawasaki disease
41. Soluble adhesion molecules and oral antigen feeding in infants
42. Islet cell antibodies are less predictive of IDDM among unaffected children in general population than in sibs of children with diabetes
43. Validity of screening for individuals at risk for type I diabetes by combined analysis of antibodies to recombinant proteins