메뉴 건너뛰기




Volumn 38, Issue 12, 1997, Pages 2436-2445

Decreased feedback regulation of low density lipoprotein receptor activity by sterols in leukemic cells from patients with acute myelogenous leukemia

Author keywords

Acute; Cholesterol; Leukemia; Myelocytic

Indexed keywords

25 HYDROXYCHOLESTEROL; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; STEROL; STEROL DERIVATIVE;

EID: 0031471267     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (43)

References (38)
  • 1
    • 0022549920 scopus 로고
    • A receptor-mediated pathway for cholesterol homeostasis
    • Brown, M. S., and J. L. Goldstein. 1986. A receptor-mediated pathway for cholesterol homeostasis. Science. 232; 34-47.
    • (1986) Science , vol.232 , pp. 34-47
    • Brown, M.S.1    Goldstein, J.L.2
  • 2
    • 0021673438 scopus 로고
    • Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol
    • Goldstein, J. L., and M. S. Brown. 1984. Progress in understanding the LDL receptor and HMG-CoA reductase, two membrane proteins that regulate the plasma cholesterol. J. Lipid Res. 25: 1450-1461.
    • (1984) J. Lipid Res. , vol.25 , pp. 1450-1461
    • Goldstein, J.L.1    Brown, M.S.2
  • 3
    • 0025120211 scopus 로고
    • Regulation of the mevalonate pathway
    • Goldstein, J. L., and M. S. Brown. 1990. Regulation of the mevalonate pathway. Nature. 343: 425-430.
    • (1990) Nature , vol.343 , pp. 425-430
    • Goldstein, J.L.1    Brown, M.S.2
  • 5
    • 0023666142 scopus 로고
    • 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter
    • Südhof, T. C., D. W. Russell, M. S. Brown, and J. L. Goldstein. 1987. 42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter. Cell. 48: 1061-1069.
    • (1987) Cell , vol.48 , pp. 1061-1069
    • Südhof, T.C.1    Russell, D.W.2    Brown, M.S.3    Goldstein, J.L.4
  • 6
    • 0023867357 scopus 로고
    • Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1
    • Dawson, P. A., S. L. Hofmann, D. R. van der Westhuyzen, T. C. Südhof, M. S. Brown, and J. L. Goldstein, 1988. Sterol-dependent repression of low density lipoprotein receptor promoter mediated by 16-base pair sequence adjacent to binding site for transcription factor Sp1. J. Biol. Chem. 263: 3372-3379.
    • (1988) J. Biol. Chem. , vol.263 , pp. 3372-3379
    • Dawson, P.A.1    Hofmann, S.L.2    Van Der Westhuyzen, D.R.3    Südhof, T.C.4    Brown, M.S.5    Goldstein, J.L.6
  • 7
    • 0027190308 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence
    • Briggs, M. R., C. Yokoyama, X. Wang, M. S. Brown, and J. L. Goldstein. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. I. Identification of the protein and delineation of its target nucleotide sequence. J. Biol. Chem. 268: 14490-14496.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14490-14496
    • Briggs, M.R.1    Yokoyama, C.2    Wang, X.3    Brown, M.S.4    Goldstein, J.L.5
  • 8
    • 0027167918 scopus 로고
    • Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization
    • Wang, X., M. R. Briggs, X. Hua, C. Yokoyama, J. L. Goldstein, and M. S. Brown. 1993. Nuclear protein that binds sterol regulatory element of low density lipoprotein receptor promoter. II. Purification and characterization. J. Biol. Chem. 268: 14497-14504.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14497-14504
    • Wang, X.1    Briggs, M.R.2    Hua, X.3    Yokoyama, C.4    Goldstein, J.L.5    Brown, M.S.6
  • 9
    • 0027490174 scopus 로고
    • SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene
    • Yokoyama, C., X. Wang, M. R. Briggs, A. Admon, J. Wu, X. Hua, J. L. Goldstein, and M. S. Brown, 1993. SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene. Cell. 75: 187-197.
    • (1993) Cell , vol.75 , pp. 187-197
    • Yokoyama, C.1    Wang, X.2    Briggs, M.R.3    Admon, A.4    Wu, J.5    Hua, X.6    Goldstein, J.L.7    Brown, M.S.8
  • 10
    • 0011176887 scopus 로고    scopus 로고
    • A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene
    • Vallett, S. M., H. B. Sanchez, J. M. Rosenfeld, and T. F. Osborne. 1996. A direct role for sterol regulatory element binding protein in activation of 3-hydroxy-3-methylglutaryl coenzyme A reductase gene. J. Biol. Chem. 271: 12247-12253.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12247-12253
    • Vallett, S.M.1    Sanchez, H.B.2    Rosenfeld, J.M.3    Osborne, T.F.4
  • 11
    • 0018181378 scopus 로고
    • Low density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells
    • Ho, Y., G. Smith, M. Brown, and J. Goldstein. 1978. Low density lipoprotein (LDL) receptor activity in human acute myelogenous leukemia cells. Blood. 52: 1099-1114.
    • (1978) Blood , vol.52 , pp. 1099-1114
    • Ho, Y.1    Smith, G.2    Brown, M.3    Goldstein, J.4
  • 12
    • 0021260784 scopus 로고
    • Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation
    • Vitols, S., G. Gahrton, A. Ost, and C. Peterson. 1984. Elevated low density lipoprotein receptor activity in leukemic cells with monocytic differentiation. Blood. 63: 1186-1193.
    • (1984) Blood , vol.63 , pp. 1186-1193
    • Vitols, S.1    Gahrton, G.2    Ost, A.3    Peterson, C.4
  • 14
    • 0022384877 scopus 로고
    • Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: Evidence from studies in patients with leukaemia
    • Vitols, S., G. Gahrton, M. Björkholm, and C. Peterson. 1985. Hypocholesterolaemia in malignancy due to elevated low-density-lipoprotein-receptor activity in tumour cells: evidence from studies in patients with leukaemia. Lancet. 2: 1150-1154.
    • (1985) Lancet , vol.2 , pp. 1150-1154
    • Vitols, S.1    Gahrton, G.2    Björkholm, M.3    Peterson, C.4
  • 15
    • 0028090689 scopus 로고
    • Multilevel regulation of low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in normal and leukemic cells
    • Vitols, S., S. Norgren, G. Juliusson, L. Tatidis, and H. Luthman. 1994. Multilevel regulation of low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression in normal and leukemic cells. Blood. 84: 2689-2698.
    • (1994) Blood , vol.84 , pp. 2689-2698
    • Vitols, S.1    Norgren, S.2    Juliusson, G.3    Tatidis, L.4    Luthman, H.5
  • 17
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • Havel, R., H. Eder, and J. Bragdon. 1955. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. J. Clin. Invest. 34: 1345-1354.
    • (1955) J. Clin. Invest. , vol.34 , pp. 1345-1354
    • Havel, R.1    Eder, H.2    Bragdon, J.3
  • 18
    • 0015348455 scopus 로고
    • The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia
    • Langer, T., W. Strober, and R. I. Levy. 1972. The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia. J. Clin. Invest. 51: 1528-1536.
    • (1972) J. Clin. Invest. , vol.51 , pp. 1528-1536
    • Langer, T.1    Strober, W.2    Levy, R.I.3
  • 20
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand. J. Clin. Lab. Invest. Supple. 97: 77-89.
    • (1968) Scand. J. Clin. Lab. Invest. Supple. , vol.97 , pp. 77-89
    • Boyum, A.1
  • 21
    • 0026736461 scopus 로고
    • Combination of an enzymatic method and HPLC for the quantitation of cholesterol in cultured cells
    • Contreras, J. A., M. Castro, C. Bocos, E. Herrera, and M. A. Lasuncion. 1992. Combination of an enzymatic method and HPLC for the quantitation of cholesterol in cultured cells. J. Lipid Res. 33: 931-936.
    • (1992) J. Lipid Res. , vol.33 , pp. 931-936
    • Contreras, J.A.1    Castro, M.2    Bocos, C.3    Herrera, E.4    Lasuncion, M.A.5
  • 22
    • 0014109162 scopus 로고
    • Lipids of human leukocytes: Relation to celltype
    • Gottfried, E. L. 1967. Lipids of human leukocytes: relation to celltype. J. Lipid Res. 8: 321-327.
    • (1967) J. Lipid Res. , vol.8 , pp. 321-327
    • Gottfried, E.L.1
  • 23
    • 0342306447 scopus 로고
    • Cholesterol as a bioregulator in the development and inhibition of leukemia
    • Inbar, M., and M. Shinitzky. 1974. Cholesterol as a bioregulator in the development and inhibition of leukemia. Proc. Natl. Acad. Sci. USA. 71: 4229-4231.
    • (1974) Proc. Natl. Acad. Sci. USA , vol.71 , pp. 4229-4231
    • Inbar, M.1    Shinitzky, M.2
  • 24
    • 0018672605 scopus 로고
    • Cholesterol, phospholipids, and fatty acids of normal immature neutrophils: Comparison with acute myeloblastic leukemia cells and normal neutrophils
    • Klock, J. C., and J. K. Pieprzyk. 1979. Cholesterol, phospholipids, and fatty acids of normal immature neutrophils: comparison with acute myeloblastic leukemia cells and normal neutrophils. J. Lipid Res. 20: 908-911.
    • (1979) J. Lipid Res. , vol.20 , pp. 908-911
    • Klock, J.C.1    Pieprzyk, J.K.2
  • 25
    • 85047690035 scopus 로고
    • Rates of cholesterol biosynthesis are related to early differentiation in acute non-lymphocytic leukemia cells
    • Yachin, S., R. A. Larson, and J. E. West. 1983. Rates of cholesterol biosynthesis are related to early differentiation in acute non-lymphocytic leukemia cells. Br. J. Haematol. 54: 459-466.
    • (1983) Br. J. Haematol. , vol.54 , pp. 459-466
    • Yachin, S.1    Larson, R.A.2    West, J.E.3
  • 26
    • 0024971244 scopus 로고
    • Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells
    • Metherall, J. E., J. L. Goldstein, K. L. Luskey, and M. S. Brown. 1989. Loss of transcriptional repression of three sterol-regulated genes in mutant hamster cells. J. Biol. Chem. 264: 15634-15641.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15634-15641
    • Metherall, J.E.1    Goldstein, J.L.2    Luskey, K.L.3    Brown, M.S.4
  • 27
    • 0028133279 scopus 로고
    • Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2
    • Yang, J., R. Sato, J. L. Goldstein, and M. S. Brown. 1994. Sterol-resistant transcription in CHO cells caused by gene rearrangement that truncates SREBP-2. Genes & Dev. 8: 1910-1919.
    • (1994) Genes & Dev. , vol.8 , pp. 1910-1919
    • Yang, J.1    Sato, R.2    Goldstein, J.L.3    Brown, M.S.4
  • 28
    • 0025741305 scopus 로고
    • A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: Cholesterol acyltransferase
    • Metherall, J. E., N. D. Ridgway, P. A. Dawson, J. L. Goldstein, and M. S. Brown. 1991. A 25-hydroxycholesterol-resistant cell line deficient in acyl-CoA: cholesterol acyltransferase. J. Biol. Chem. 266: 12734-12740.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12734-12740
    • Metherall, J.E.1    Ridgway, N.D.2    Dawson, P.A.3    Goldstein, J.L.4    Brown, M.S.5
  • 29
    • 15844418021 scopus 로고    scopus 로고
    • Complementation of mutation in acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells
    • Cao, G., J. L. Goldstein, and M. S. Brown. 1996. Complementation of mutation in acyl-CoA:cholesterol acyltransferase (ACAT) fails to restore sterol regulation in ACAT-defective sterol-resistant hamster cells. J. Biol. Chem. 271: 14642-14648.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14642-14648
    • Cao, G.1    Goldstein, J.L.2    Brown, M.S.3
  • 30
    • 0029946926 scopus 로고    scopus 로고
    • 27-Hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7α,27-dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of LDL cholesterol can underlie a defective feedback control in malignant cells
    • Axelson, M., and O. Larsson. 1996. 27-Hydroxylated low density lipoprotein (LDL) cholesterol can be converted to 7α,27-dihydroxy-4-cholesten-3-one (cytosterone) before suppressing cholesterol production in normal human fibroblasts. Evidence that an altered metabolism of LDL cholesterol can underlie a defective feedback control in malignant cells. J. Biol. Chem. 271: 12724-12736.
    • (1996) J. Biol. Chem. , vol.271 , pp. 12724-12736
    • Axelson, M.1    Larsson, O.2
  • 31
    • 0024509498 scopus 로고
    • Mechanism of the growth-related activation of the low density lipoprotein receptor pathway
    • Mazzone, T., K. Basheeruddin, L. Ping, S. Frazer, and G. S. Getz. 1989. Mechanism of the growth-related activation of the low density lipoprotein receptor pathway. J. Biol. Chem. 264: 1787-1792.
    • (1989) J. Biol. Chem. , vol.264 , pp. 1787-1792
    • Mazzone, T.1    Basheeruddin, K.2    Ping, L.3    Frazer, S.4    Getz, G.S.5
  • 32
    • 0024423258 scopus 로고
    • Inhibitors of translation induce low density lipoprotein receptor gene expression in human skin fibroblasts
    • Mazzone, T., K. Basheeruddin, and H. Duncan. 1989. Inhibitors of translation induce low density lipoprotein receptor gene expression in human skin fibroblasts. J. Biol. Chem. 264: 15529-15534.
    • (1989) J. Biol. Chem. , vol.264 , pp. 15529-15534
    • Mazzone, T.1    Basheeruddin, K.2    Duncan, H.3
  • 33
    • 0025239760 scopus 로고
    • Relation of growth- and sterol-related regulatory pathways for low density lipoprotein receptor gene expression
    • Mazzone, T., K. Basheeruddin, L. Ping, and C. Schick. 1990. Relation of growth- and sterol-related regulatory pathways for low density lipoprotein receptor gene expression. J. Biol. Chem. 265: 5145-5149.
    • (1990) J. Biol. Chem. , vol.265 , pp. 5145-5149
    • Mazzone, T.1    Basheeruddin, K.2    Ping, L.3    Schick, C.4
  • 34
    • 0025606532 scopus 로고
    • Mitogenic stimulation alters the regulation of LDL receptor gene expression in human lymphocytes
    • Cuthbert, J. A., and P. E. Lipsky. 1990. Mitogenic stimulation alters the regulation of LDL receptor gene expression in human lymphocytes. J. Lipid Res. 31: 2067-2078.
    • (1990) J. Lipid Res. , vol.31 , pp. 2067-2078
    • Cuthbert, J.A.1    Lipsky, P.E.2
  • 35
    • 0026082680 scopus 로고
    • Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers
    • Roth, M., L. R. Emmons, A. Perruchoud, and L. H. Block. 1991. Expressions of the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes are stimulated by recombinant platelet-derived growth factor isomers. Proc. Natl. Acad. Sci. USA. 88: 1888-1892.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1888-1892
    • Roth, M.1    Emmons, L.R.2    Perruchoud, A.3    Block, L.H.4
  • 36
    • 0028047054 scopus 로고
    • Non-sterol regulation of low density lipoprotein receptor gene expression in T cells
    • Makar, R. S., P. E. Lipsky, and J. A. Cuthbert. 1994. Non-sterol regulation of low density lipoprotein receptor gene expression in T cells. J. Lipid Res. 35: 1888-1895.
    • (1994) J. Lipid Res. , vol.35 , pp. 1888-1895
    • Makar, R.S.1    Lipsky, P.E.2    Cuthbert, J.A.3
  • 37
    • 0018568220 scopus 로고
    • Effect of cell density on binding and uptake of low density lipoprotein by human fibroblasts
    • Kruth, H. S., J. Avigan, W. Gamble, and M. Vaughan. 1979. Effect of cell density on binding and uptake of low density lipoprotein by human fibroblasts. J. Cell. Biol. 83: 588-594.
    • (1979) J. Cell. Biol. , vol.83 , pp. 588-594
    • Kruth, H.S.1    Avigan, J.2    Gamble, W.3    Vaughan, M.4
  • 38
    • 0026334064 scopus 로고
    • Uptake of low-density lipoprotein by malignant cells - Possible therapeutic applications
    • Vitols, S. 1991. Uptake of low-density lipoprotein by malignant cells - possible therapeutic applications. Cancer Cells. 3: 488-495.
    • (1991) Cancer Cells , vol.3 , pp. 488-495
    • Vitols, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.