The effect of high-intensity exhaustive exercise studied in isolated mitochondria from human skeletal muscle

Pflugers Archiv European Journal of Physiology

Volumn 443, Issue 2, 2001, Pages 180-187

  Rasmussen, Ulla F ^a   Krustrup, Peter ^b   Bangsbo, Jens ^b   Rasmussen, Hans N ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Bicycle exercise; Cytochromes; Fatigue; Lactate; Oxidative phosphorylation; Oxygen uptake; Quadriceps muscle; Respiration

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; GLUTAMATE DEHYDROGENASE; GLUTAMIC ACID; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; OXOGLUTARATE DEHYDROGENASE; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; SUCCINATE DEHYDROGENASE; SUCCINIC ACID;

ADULT; ARTICLE; BICYCLE ERGOMETER; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; EXERCISE; EXHAUSTION; FATTY ACID OXIDATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; MITOCHONDRIAL RESPIRATION; MUSCLE FATIGUE; MUSCLE MITOCHONDRION; NORMAL HUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL;

ACYLTRANSFERASES; ADULT; EXERCISE; GLUTAMATE DEHYDROGENASE; GLYCEROLPHOSPHATE DEHYDROGENASE; HUMANS; KETOGLUTARATE DEHYDROGENASE COMPLEX; MALE; MITOCHONDRIA, MUSCLE; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; NADH, NADPH OXIDOREDUCTASES; OXIDATION-REDUCTION; PHYSICAL ENDURANCE; PYRUVATE DEHYDROGENASE (LIPOAMIDE);

EID: 0035191839     PISSN: 00316768     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004240100689     Document Type: Article

References (55)

1. Elevated muscle acidity and energy production during exhaustive exercise in humans
2. Fatty acid oxidation by liver and muscle preparations of exhaustively exercised rats
3. Mitochondrial transport of cations: Channels, exchangers, and permeability transition
4. Perspectives on the mitochondrial permeability transition
5. Reversal of impaired oxidative phosphorylation and calcium overloading in the skeletal muscle mitochondria of CHF-146 dystrophic hamsters
6. Effect of exercise on hexokinase distribution and mitochondrial respiration in skeletal muscle
7. Leg muscle pH following sprint running
8. Mitochondrial intermembrane junctional complexes and their role in cell death
9. Mitochondrial function as a determinant of recovery or death in cell response to injury
10. Effects of exercise, training, and diet on muscle citric acid cycle enzyme activity
11. Effects of exercise on activity of heart and muscle mitochondria
12. Contributions of mitochondria to animal physiology: From homeostatic sensor to calcium signalling and cell death
13. Progress on the mitochondrial permeability transition pore: Regulation by complex I and ubiquinone analogs
14. Improving lactate analysis with the YSI 2300 GL: Hemolyzing blood samples makes results comparable with those for deproteinized whole blood
15. Increased exo-NADH oxidase activity in skeletal muscle mitochondria from humans with malignant hyperthermia susceptibility
16. The effect of high-intensity exercise on the respiratory capacity of skeletal muscle
17. Effect of exercise and training on mitochondria of rat skeletal muscle
18. Mitochondrial calcium transport: Mechanisms and functions
19. 2+ signalling between sarco-endoplasmic reticulum and mitochondria
20. The mitochondrial permeability transition: Its molecular mechanism and role in reperfusion injury
21. Role of mitochondrial calcium transport in the control of substrate oxidation
22. Haematin compounds
23. Blood and muscle pH after maximal exercise in man
24. Fluctuations in mitochondrial membrane potential caused by repetitive gating of the permeability transition pore
25. From calcium signalling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state
26. The ferricyanide method for elucidating the sidedness of membrane-bound dehydrogenases
27. 2+ concentration
28. Effect of acute and exhaustive exercise upon the fine structure of heart mitochondria
29. Acute exercise and skeletal muscle antioxidant and metabolic enzymes: Effects of fiber type and age
30. Calcium content and respiratory control index of skeletal muscle mitochondria during exercise and recovery
31. Buffer capacity of deproteinized human vastus lateralis muscle
32. Carnitine-acylcarnitine translocase in ischemia: Evidence for sulfhydryl modification
33. Transient and long-lasting openings of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcein fluorescence
34. Mitochondrial enzyme activities
35. Regular training modulates the accumulation of reactive carbonyl derivatives in mitochondrial and cytosolic fractions of rat skeletal muscle
36. Optimization of preparation of mitochondria from 25-100 mg skeletal muscle
37. Respiration measurements in small scale
38. Small scale preparation of skeletal muscle mitochondria, criteria of integrity, and assays with reference to tissue function
39. The NADH oxidase system (external) of muscle mitochondria and its role in the oxidation of cytoplasmic NADH
40. Human quadriceps muscle mitochondria: A functional characterization
41. Human skeletal muscle mitochondrial capacity
42. Characterization of mitochondria from pig muscle: Higher activity of exo-NADH oxidase in animals suffering from malignant hyperthermia
43. Aerobic metabolism of human quadriceps muscle: In vivo data parallel measurements on isolated mitochondria
44. Mitochondria as all-round players of the calcium game
45. Mitochondria as biosensors of calcium microdomains
46. A rapid, sensitive, and specific method for the determination of protein in dilute solution
47. Citrate synthase from rat liver
48. 31PMRS methods during exercise and recovery in men
49. +-dependent inner-membrane permeability transition
50. Increased activity of citrate synthase in human skeletal muscle after a single bout of prolonged exercise
51. Mitochondrial oxidative function in human saponin-skinned muscle fibres: Effects of prolonged exercise
52. Mitochondrial function in human skeletal muscle is not impaired by high intensity exercise
53. The mitochondrial permeability transition