Antifibrotic action of Cu/Zn SOD is mediated by TGF-β1 repression and phenotypic reversion of myofibroblasts

Free Radical Biology and Medicine

Volumn 30, Issue 1, 2001, Pages 30-42

  Vozenin Brotons, Marie Catherine ^a   Sivan, Virginie ^a,b   Gault, Nathalie ^a   Renard, Christine ^a   Geffrotin, Claudine ^a   Delanian, Sylvie ^c   Lefaix, Jean Louis ^a   Martin, Michèle ^a,d  

^a CEA SACLAY   (France)

^b FRACTAL   (France)

^c Hôpital Tenon   (France)

^d DIF   (France)

Author keywords

Actin; Extracell ular matrix; Fibrosis; Free radicals; Myofibroblast; Radiation; Skin; Superoxide dismutase; TGF

Indexed keywords

ANTIOXIDANT; BETA ACTIN; COLLAGEN TYPE 1; COPPER ZINC SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE; TENASCIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL DEATH; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSKELETON; DRUG ACTIVITY; DRUG MECHANISM; EXTRACELLULAR MATRIX; IN VITRO STUDY; MYOFIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SKIN FIBROBLAST; SKIN FIBROSIS; SWINE;

ACTINS; ANIMALS; APOPTOSIS; CELL COUNT; COLLAGEN; FIBROBLASTS; FIBROSIS; GENE EXPRESSION REGULATION; MODELS, BIOLOGICAL; PHENOTYPE; SKIN; SUPEROXIDE DISMUTASE; SWINE; TENASCIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035188895     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(00)00431-7     Document Type: Article

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