Suppression of proliferation of human coronary artery smooth muscle cells by the nitric oxide donor, S-nitrosoglutathione, is cGMP-independent

Molecular Cell Biology Research Communications

Volumn 4, Issue 1, 2000, Pages 32-36

  Young, Delano V ^a   Serebryanik, Diana ^a   Janero, David R ^a   Tam, S William ^a  

^a NitroMed Inc   (United States)

Author keywords

Cyclic GMP; Human coronary artery smooth muscle cells; Nitric oxide; S nitrosoglutathione; Suppression of proliferation

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CYCLIC GMP; GUANYLATE CYCLASE; NITRIC OXIDE DONOR; S NITROSOGLUTATHIONE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY DISEASE; CYTOSTASIS; CYTOTOXICITY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RABBIT; REGULATORY MECHANISM; SMOOTH MUSCLE FIBER; SWINE; SYNTHESIS;

ORYCTOLAGUS CUNICULUS; SUIDAE;

EID: 0035173365     PISSN: 15224724     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcbr.2000.0254     Document Type: Article

References (28)

1. Nitric oxide and the proliferation of vascular smooth muscle cells
2. The vascular biology of nitric oxide and its role in atherogenesis
3. Nitric oxide and its role in hemostasis
4. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
5. Mechanisms of nitrosothiol-induced antimitogenesis in aortic smooth muscle cells
6. NO increases protein tyrosine phosphatase activity in smooth muscle cells: Relationship to antimitogenesis
7. Nitric oxide-induced downregulation of cdk2 activity and cyclin A gene transcription in vascular smooth muscle cells
8. Nebivolol, a nitric oxide releasing β-adrenergic antagonist and NCX 4016, a nitric oxide releasing aspirin derivative inhibit proliferation of cultured rat aortic smooth muscle cells
9. Dual cell cycle-specific mechanisms mediate the antimitogenic effects of nitric oxide in vascular smooth muscle cells
10. 2+ mobilization by cyclic AMP and GMP in rabbit aortic smooth muscle cells
11. Antiproliferative action of cyclic GMP-elevating vasodilators in cultured rabbit aortic smooth muscle cells
12. Nitric oxide modulates expression of cell cycle regulatory proteins. A cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation
13. Sdi1/Cip1/Waf1 by nitric oxide-generating vasodilator in vascular smooth muscle cells
14. Adenovirus-mediated gene transfer of cGMP-dependent protein kinase increases the sensitivity of cultured vascular smooth muscle cells to the antiproliferative and pro-apoptotic effects of nitric oxide/cGMP
15. Nitric oxide as a signaling molecule in the vascular system: An overview
16. Loss of expression of the beta subunit of soluble guanylyl cyclase prevents nitric oxide-mediated inhibition of DNA synthesis in smooth muscle cells of old rats
17. cGMP elevating agents suppress proliferation of vascular smooth muscle cells by inhibiting the activation of epidermal growth factor signaling pathway
18. Inducible nitric oxide synthase (iNOS) expression upregulates p21 and inhibits vascular smooth muscle cell proliferation through p42/44 mitogen-activated protein kinase activation and independent of p53 and cyclic guanosine monophosphate
19. Nitric oxide (NO)-related pharmaceuticals: Contemporary approaches to therapeutic NO modulation
20. The effects of exogenous nitric oxide on smooth muscle cell proliferation following porcine carotid angioplasty
21. Nitrosylated bovine serum albumin derivatives as pharmacologically active nitric oxide congeners
22. Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide
23. Nitric oxide (NO) donor molecules: Effect of NO release rate on vascular smooth muscle cell proliferation in vitro
24. Nitric oxide-cyclic GMP pathway regulates vascular smooth muscle cell phenotypic modulation: Implications in vascular diseases
25. Nitric oxide inhibits Oct-1 DNA binding activity in cultured vascular smooth muscle cells
26. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases
27. Inactivation of ribonucleotide reductase by nitric oxide
28. Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP