Fluorometric determination of 2′-β-fluoro-2′,3′-dideoxyadenosine 5′-triphosphate, the active metabolite of a new anti-human immunodeficiency virus drug, in human lymphocytes

Analytical Biochemistry

Volumn 288, Issue 1, 2001, Pages 52-61

  Dai, Fang ^a   Kelley, James A ^a   Zhang, Heping ^a   Malinowski, Nancy ^a   Kavlick, Mark F ^a   Lietzau, Jill ^a   Welles, Lauri ^a   Yarchoan, Robert ^a   Ford Jr , Harry ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

2 fluoro 2 ,3 dideoxyadenosine; 2 fluo ro 2 ,3 dideoxyadenosine 5 triphosphate; AIDS; Fluorescence; HPLC

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; FLUORESCENCE; ION CHROMATOGRAPHY; LYMPHOCYTES; METABOLITES; MOLECULAR BIOLOGY; NUCLEIC ACIDS; PATIENT MONITORING; PATIENT TREATMENT; VIRUSES;

AIDS; FLUORESCENCE DETECTION; FLUOROMETRIC DETERMINATION; HPLC; HUMAN IMMUNODEFICIENCY VIRUS; PERIPHERAL BLOOD MONONUCLEAR CELLS; PRECOLUMN DERIVATIZATIONS; TRIPHOSPHATE;

DISEASES;

2',3' DIDEOXY 2' FLUOROADENOSINE; ABACAVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DIDANOSINE; PURINE; PYRIMIDINE DERIVATIVE;

ARTICLE; FLUORESCENCE; FLUOROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LYMPHOCYTE; PRIORITY JOURNAL; VIRUS INFECTION;

EID: 0035172943     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2000.4862     Document Type: Article

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