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Volumn 25, Issue 7, 1997, Pages 893-896

Decay rates of anti-HIV dideoxynucleotides in tissue culture systems: A simple correction for the effect of cell replication

Author keywords

[No Author keywords available]

Indexed keywords

2',3' DIDEOXYADENOSINE; DIDANOSINE; TRITIUM;

EID: 0030806971     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (14)
  • 1
    • 0025997616 scopus 로고
    • Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells
    • Y. Törnevik, B. Jacobsson, S. Britton, and S. Eriksson: Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells. AIDS Res. Human Retroviruses 7, 751-759 (1991).
    • (1991) AIDS Res. Human Retroviruses , vol.7 , pp. 751-759
    • Törnevik, Y.1    Jacobsson, B.2    Britton, S.3    Eriksson, S.4
  • 2
    • 0025344520 scopus 로고
    • Cellular pharmacology of 2′,3′-didehydro-2′,3′-dideoxythymidine (D4T) in human peripheral blood mononuclear cells
    • Z. Zhu, H.-T. Ho, M. J. Hitchcock, and J.-P. Sommadossi: Cellular pharmacology of 2′,3′-didehydro-2′,3′-dideoxythymidine (D4T) in human peripheral blood mononuclear cells. Biochem. Pharmacol. 39, R15-R19 (1990).
    • (1990) Biochem. Pharmacol. , vol.39
    • Zhu, Z.1    Ho, H.-T.2    Hitchcock, M.J.3    Sommadossi, J.-P.4
  • 5
    • 0006621161 scopus 로고
    • Activation of 2′-fluoro-2′,3′-dideoxyarabinosyladenine (FddA), an anti-HIV agent, in both quiescent and PHA-activated human peripheral blood mononuclear cells (PBMC)
    • H.-T. Ho, K. L. Woods, M. Mansuri, and M. J. M. Hitchcock: Activation of 2′-fluoro-2′,3′-dideoxyarabinosyladenine (FddA), an anti-HIV agent, in both quiescent and PHA-activated human peripheral blood mononuclear cells (PBMC). Antiviral Res. 15 (Suppl. 1), 95 (1991).
    • (1991) Antiviral Res. , vol.15 , Issue.1 SUPPL. , pp. 95
    • Ho, H.-T.1    Woods, K.L.2    Mansuri, M.3    Hitchcock, M.J.M.4
  • 6
    • 0025337365 scopus 로고
    • Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM)
    • A. Fridland, M. C. Connelly, and R. Ashmun: Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM). Mol. Pharmacol. 37, 665-670 (1990).
    • (1990) Mol. Pharmacol. , vol.37 , pp. 665-670
    • Fridland, A.1    Connelly, M.C.2    Ashmun, R.3
  • 8
    • 0024405549 scopus 로고
    • Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus
    • H.-T. Ho and M. J. M. Hitchcock: Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus. Antimicrob. Agents Chemother. 33, 844-849 (1989).
    • (1989) Antimicrob. Agents Chemother. , vol.33 , pp. 844-849
    • Ho, H.-T.1    Hitchcock, M.J.M.2
  • 10
    • 0027471409 scopus 로고
    • Anomalous accumulation and decay of 2′,3′-dideoxyadenosine-5′-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2′,3′-dideoxyinosine
    • G. Ahluwalia, D. A. Cooney, N. R. Hartman, H. Mitsuya, R. Yarchoan, A. Fridland, S. Broder, and D. G. Johns: Anomalous accumulation and decay of 2′,3′-dideoxyadenosine-5′-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2′,3′-dideoxyinosine. Drug Metab. Dispos. 21, 369-376 (1993).
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 369-376
    • Ahluwalia, G.1    Cooney, D.A.2    Hartman, N.R.3    Mitsuya, H.4    Yarchoan, R.5    Fridland, A.6    Broder, S.7    Johns, D.G.8
  • 11
    • 0027096272 scopus 로고
    • Metabolic pathways for the activation of the antiviral agent 2′,3′-dideoxyguanosine in human lymphoid cells
    • L. L. Bondoc, Jr., G. Ahluwalia, D. A. Cooney, N. R. Hartman, D. G. Johns, and A. Fridland: Metabolic pathways for the activation of the antiviral agent 2′,3′-dideoxyguanosine in human lymphoid cells. Mol. Pharmacol. 42, 525-530 (1992).
    • (1992) Mol. Pharmacol. , vol.42 , pp. 525-530
    • Bondoc Jr., L.L.1    Ahluwalia, G.2    Cooney, D.A.3    Hartman, N.R.4    Johns, D.G.5    Fridland, A.6
  • 13
    • 0025128885 scopus 로고
    • Cytostatic effects of 2′,3′-dideoxyribonucleosides on transformed human hemopoietic cell lines
    • R. L. Blakley, F. C. Harwood, and K. D. Huff: Cytostatic effects of 2′,3′-dideoxyribonucleosides on transformed human hemopoietic cell lines. Mol. Pharmacol. 37, 328-332 (1990).
    • (1990) Mol. Pharmacol. , vol.37 , pp. 328-332
    • Blakley, R.L.1    Harwood, F.C.2    Huff, K.D.3
  • 14
    • 0000468828 scopus 로고
    • Biochemical pharmacology of 2′-fluoro-2′,3′-dideoxyarabinosyladenine, an inhibitor of HIV with improved metabolic and chemical stability over 2′,3′-dideoxyadenosine
    • M. J. M. Hitchcock, K. Woods, H. DeBoeck, and H.-T. Ho: Biochemical pharmacology of 2′-fluoro-2′,3′-dideoxyarabinosyladenine, an inhibitor of HIV with improved metabolic and chemical stability over 2′,3′-dideoxyadenosine. Antiviral Chem. Chemother. 1, 319-327 (1990).
    • (1990) Antiviral Chem. Chemother. , vol.1 , pp. 319-327
    • Hitchcock, M.J.M.1    Woods, K.2    DeBoeck, H.3    Ho, H.-T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.