-
1
-
-
0025997616
-
Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells
-
Y. Törnevik, B. Jacobsson, S. Britton, and S. Eriksson: Intracellular metabolism of 3′-azidothymidine in isolated human peripheral blood mononuclear cells. AIDS Res. Human Retroviruses 7, 751-759 (1991).
-
(1991)
AIDS Res. Human Retroviruses
, vol.7
, pp. 751-759
-
-
Törnevik, Y.1
Jacobsson, B.2
Britton, S.3
Eriksson, S.4
-
2
-
-
0025344520
-
Cellular pharmacology of 2′,3′-didehydro-2′,3′-dideoxythymidine (D4T) in human peripheral blood mononuclear cells
-
Z. Zhu, H.-T. Ho, M. J. Hitchcock, and J.-P. Sommadossi: Cellular pharmacology of 2′,3′-didehydro-2′,3′-dideoxythymidine (D4T) in human peripheral blood mononuclear cells. Biochem. Pharmacol. 39, R15-R19 (1990).
-
(1990)
Biochem. Pharmacol.
, vol.39
-
-
Zhu, Z.1
Ho, H.-T.2
Hitchcock, M.J.3
Sommadossi, J.-P.4
-
3
-
-
0024349612
-
In vivo activity against HIV and favorable toxicity profile of 2′,3′-dideoxyinosine
-
R. Yarchoan, H. Mitsuya, R. V. Thomas, J. M. Pluda, N. R. Hartman, C.-F. Perno, K. S. Marczyk, J.-P. Allain, D. G. Johns, and S. Broder: In vivo activity against HIV and favorable toxicity profile of 2′,3′-dideoxyinosine. Science 245, 412-415 (1989).
-
(1989)
Science
, vol.245
, pp. 412-415
-
-
Yarchoan, R.1
Mitsuya, H.2
Thomas, R.V.3
Pluda, J.M.4
Hartman, N.R.5
Perno, C.-F.6
Marczyk, K.S.7
Allain, J.-P.8
Johns, D.G.9
Broder, S.10
-
4
-
-
0025319786
-
Fluoro-2′,3′-dideoxyarabinosyladenine: A metabolically stable analogue of the antiretroviral agent 2′,3′-dideoxyadenosine
-
R. Musood, G. S. Ahluwalia, D. A. Cooney, A. Fridland, V. E. Marquez, J. S. Driscoll, Z. Hao, H. Mitsuya, C.-F. Perno, S. Broder, and D. G. Johns: Fluoro-2′,3′-dideoxyarabinosyladenine: a metabolically stable analogue of the antiretroviral agent 2′,3′-dideoxyadenosine. Mol. Pharmacol. 37, 590-596 (1990).
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 590-596
-
-
Musood, R.1
Ahluwalia, G.S.2
Cooney, D.A.3
Fridland, A.4
Marquez, V.E.5
Driscoll, J.S.6
Hao, Z.7
Mitsuya, H.8
Perno, C.-F.9
Broder, S.10
Johns, D.G.11
-
5
-
-
0006621161
-
Activation of 2′-fluoro-2′,3′-dideoxyarabinosyladenine (FddA), an anti-HIV agent, in both quiescent and PHA-activated human peripheral blood mononuclear cells (PBMC)
-
H.-T. Ho, K. L. Woods, M. Mansuri, and M. J. M. Hitchcock: Activation of 2′-fluoro-2′,3′-dideoxyarabinosyladenine (FddA), an anti-HIV agent, in both quiescent and PHA-activated human peripheral blood mononuclear cells (PBMC). Antiviral Res. 15 (Suppl. 1), 95 (1991).
-
(1991)
Antiviral Res.
, vol.15
, Issue.1 SUPPL.
, pp. 95
-
-
Ho, H.-T.1
Woods, K.L.2
Mansuri, M.3
Hitchcock, M.J.M.4
-
6
-
-
0025337365
-
Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM)
-
A. Fridland, M. C. Connelly, and R. Ashmun: Relationship of deoxynucleotide changes to inhibition of DNA synthesis induced by the antiretroviral agent 3′-azido-3′-deoxythymidine and release of its monophosphate by human lymphoid cells (CCRF-CEM). Mol. Pharmacol. 37, 665-670 (1990).
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 665-670
-
-
Fridland, A.1
Connelly, M.C.2
Ashmun, R.3
-
7
-
-
0022471697
-
Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity
-
D. A. Cooney, M. Dalai, H. Mitsuya, J. B. McMahon, M. Nadkarni, J. Balzarini, S. Broder, and D. G. Johns: Initial studies on the cellular pharmacology of 2′,3′-dideoxycytidine, an inhibitor of HTLV-III infectivity. Biochem. Pharmacol. 35, 2065-2068 (1986).
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 2065-2068
-
-
Cooney, D.A.1
Dalai, M.2
Mitsuya, H.3
McMahon, J.B.4
Nadkarni, M.5
Balzarini, J.6
Broder, S.7
Johns, D.G.8
-
8
-
-
0024405549
-
Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus
-
H.-T. Ho and M. J. M. Hitchcock: Cellular pharmacology of 2′,3′-dideoxy-2′,3′-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus. Antimicrob. Agents Chemother. 33, 844-849 (1989).
-
(1989)
Antimicrob. Agents Chemother.
, vol.33
, pp. 844-849
-
-
Ho, H.-T.1
Hitchcock, M.J.M.2
-
9
-
-
0026740310
-
Cellular metabolism of (-)enantiomeric 2′-deoxy-3′-thiacytidine
-
N. Cammack, P. Rouse, C. L. P. Marr, P. J. Reid, R. E. Boehme, J. A. V. Coates, C. R. Penn, and J. M. Cameron: Cellular metabolism of (-)enantiomeric 2′-deoxy-3′-thiacytidine. Biochem. Pharmacol. 43, 2059-2064 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 2059-2064
-
-
Cammack, N.1
Rouse, P.2
Marr, C.L.P.3
Reid, P.J.4
Boehme, R.E.5
Coates, J.A.V.6
Penn, C.R.7
Cameron, J.M.8
-
10
-
-
0027471409
-
Anomalous accumulation and decay of 2′,3′-dideoxyadenosine-5′-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2′,3′-dideoxyinosine
-
G. Ahluwalia, D. A. Cooney, N. R. Hartman, H. Mitsuya, R. Yarchoan, A. Fridland, S. Broder, and D. G. Johns: Anomalous accumulation and decay of 2′,3′-dideoxyadenosine-5′-triphosphate in human T-cell cultures exposed to the anti-HIV drug 2′,3′-dideoxyinosine. Drug Metab. Dispos. 21, 369-376 (1993).
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 369-376
-
-
Ahluwalia, G.1
Cooney, D.A.2
Hartman, N.R.3
Mitsuya, H.4
Yarchoan, R.5
Fridland, A.6
Broder, S.7
Johns, D.G.8
-
11
-
-
0027096272
-
Metabolic pathways for the activation of the antiviral agent 2′,3′-dideoxyguanosine in human lymphoid cells
-
L. L. Bondoc, Jr., G. Ahluwalia, D. A. Cooney, N. R. Hartman, D. G. Johns, and A. Fridland: Metabolic pathways for the activation of the antiviral agent 2′,3′-dideoxyguanosine in human lymphoid cells. Mol. Pharmacol. 42, 525-530 (1992).
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 525-530
-
-
Bondoc Jr., L.L.1
Ahluwalia, G.2
Cooney, D.A.3
Hartman, N.R.4
Johns, D.G.5
Fridland, A.6
-
12
-
-
0027328702
-
Characterization of 2′,3′-dideoxycytidine diphosphocholine and 2′,3′-dideoxycytidine diphosphoethanolamine
-
Z. Hao, E. E. Stowe, G. Ahluwalia, D. C. Baker, A. K. Hebbler, C. Chisena, S. M. Musser, J. A. Kelley, C.-F. Perno, D. G. Johns, and D. A. Cooney: Characterization of 2′,3′-dideoxycytidine diphosphocholine and 2′,3′-dideoxycytidine diphosphoethanolamine. Drug Metab. Dispos. 21, 738-744 (1993).
-
(1993)
Drug Metab. Dispos.
, vol.21
, pp. 738-744
-
-
Hao, Z.1
Stowe, E.E.2
Ahluwalia, G.3
Baker, D.C.4
Hebbler, A.K.5
Chisena, C.6
Musser, S.M.7
Kelley, J.A.8
Perno, C.-F.9
Johns, D.G.10
Cooney, D.A.11
-
13
-
-
0025128885
-
Cytostatic effects of 2′,3′-dideoxyribonucleosides on transformed human hemopoietic cell lines
-
R. L. Blakley, F. C. Harwood, and K. D. Huff: Cytostatic effects of 2′,3′-dideoxyribonucleosides on transformed human hemopoietic cell lines. Mol. Pharmacol. 37, 328-332 (1990).
-
(1990)
Mol. Pharmacol.
, vol.37
, pp. 328-332
-
-
Blakley, R.L.1
Harwood, F.C.2
Huff, K.D.3
-
14
-
-
0000468828
-
Biochemical pharmacology of 2′-fluoro-2′,3′-dideoxyarabinosyladenine, an inhibitor of HIV with improved metabolic and chemical stability over 2′,3′-dideoxyadenosine
-
M. J. M. Hitchcock, K. Woods, H. DeBoeck, and H.-T. Ho: Biochemical pharmacology of 2′-fluoro-2′,3′-dideoxyarabinosyladenine, an inhibitor of HIV with improved metabolic and chemical stability over 2′,3′-dideoxyadenosine. Antiviral Chem. Chemother. 1, 319-327 (1990).
-
(1990)
Antiviral Chem. Chemother.
, vol.1
, pp. 319-327
-
-
Hitchcock, M.J.M.1
Woods, K.2
DeBoeck, H.3
Ho, H.-T.4
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