Thymidine kinase-independent intracellular delivery of bioactive nucleotides by aryl phosphate derivatives of bromo-methoxy zidovudine (compounds WHI-05 and WHI-07) in normal human female genital tract epithelial cells and sperm

Biology of Reproduction

Volumn 64, Issue 1, 2001, Pages 51-59

  D'Cruz, O J ^a   Venkatachalam, T K ^a   Uckun, F M ^a  

^a PARKER HUGHES INSTITUTE   (United States)

Author keywords

Female reproductive tract; Gamete biology kinases; Sperm; Vagina

Indexed keywords

5 BROMO 6 METHOXY 5,6 DIHYDRO 3' AZIDOTHYMIDINE 4' (4 BROMOPHENYL)METHOXYALANYLPHOSPHATE; 5 BROMO 6 METHOXY 5,6 DIHYDRO 3' AZIDOTHYMIDINE 5' (4 METHOXYPHENYL)METHOXYALANYLPHOSPHATE; ANTIRETROVIRUS AGENT; SPERMICIDAL AGENT; THYMIDINE KINASE; UNCLASSIFIED DRUG; WHI 05; WHI 07; ZIDOVUDINE DERIVATIVE;

ARTICLE; CONTRACEPTION; DRUG METABOLISM; ENZYME ACTIVITY; FEMALE; FEMALE GENITAL SYSTEM; FLOW CYTOMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MALE; PRIORITY JOURNAL; SPERM; UTERINE CERVIX EPITHELIUM; VAGINA EPITHELIUM;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0035172543     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod64.1.51     Document Type: Article

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