Apoptotic change and NOS activity in the experimental animal diffuse axonal injury model

Yonsei Medical Journal

Volumn 42, Issue 5, 2001, Pages 518-526

  Park, Chong Oon ^a   Yi, Hyeon Gyu ^a  

^a Inha University School of Medicine   (South Korea)

Author keywords

Apoptosis; DAI; Nitric oxide synthase; TUNEL stain

Indexed keywords

AGAROSE; COMPLEMENTARY DNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; DIFFUSE AXONAL INJURY; DISEASE SEVERITY; ELECTROPHORESIS; ENZYME ACTIVITY; GEL; GENE AMPLIFICATION; HISTOCHEMISTRY; HISTOPATHOLOGY; MALE; NICK END LABELING; NONHUMAN; PATHOGENESIS; PATHOPHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TUBE; WEIGHT;

EID: 0035169499     PISSN: 05135796     EISSN: None     Source Type: Journal    
DOI: 10.3349/ymj.2001.42.5.518     Document Type: Article

References (35)

1. Nitric oxide synthase regulatory sites; Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase, and calcium /calmodulin protein kinase; identification of flavin and calmodulin binding sites
2. Nitric oxide
3. Formation of nitric oxide from L-arginine in the Central nervous system: A transduction mechanism for stimulation of the soluble guanylate cyclase
4. Vascular endothelial cells synthesize nitric oxide from L-arginine
5. Nitric oxide synthases: Properties and catalytic mechanism
6. Nitric oxide: Biosynthesis and biological significance
7. Nitric oxide: Physiology, pathophysiology, and pharmacology
8. Role of nitric oxide in traumatic brain injury in the rat
9. Compex role of nitric oxide in cerebral ischemia
10. Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and the ugly
11. Nitric oxide neurotoxicity
12. Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors
13. Dual role of nitric oxide in focal cerebral ischemia
14. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
15. Inducible but constitutive production of nitric oxide by vascular smooth muscle cells
16. Marked Induction of calcium-independent nitic oxide synthase activity after focal cerebral ischemia
17. Apoptotic DNA fragmentation in the rat cerebral cortex induced by permanent middle cerebral artery occlusion
18. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
19. Immunochemical location of inducible nitric oxide synthase in edotoxin-treated rats
20. A new model of diffuse brain injury in rats
21. The effects of methylprednisolone on prevention of brain edema after experimental moderate diffuse brain injury in rats
22. Suppression of Flavin-containing monooxygenase by overproduced nitric oxide in rat liver
23. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
24. A novel neuronal messenger in brain: The free radical, nitric oxide
25. Anti-inflammatory glucocorticoid inhibit the induction by endotoxin of nitric oxide synthase in the lung, liver and aorta of the rat
26. Synthesis of nitric oxide in CNS glial cells
27. Nitric oxide: Pathophysiological mechanism
28. Inhibition of tumor cell ribonucleotide reductase by macrophage-derived nitric oxide
29. Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurones after focal cerebral ischemia in rat
30. A comparative study of the effects of two nitric oxide synthase inhibitors and two nitric oxide donors on temporary focal cerebral ischemia in the Wistar rat
31. Experimental brain injury induces regionally distinct apoptosis during the acute and delayed post-traumatic period
32. Apoptosis: A different type of cell death
33. Do all programmed cell deaths occur via apoptosis?
34. Aurintricarboxylic acid protects hippocampal neurons from glutamate excitotoxicity in vitro
35. Aurintricarboxylic acid protects hippocampal neurons from induced toxicity in vivo