메뉴 건너뛰기




Volumn 56, Issue 3, 1999, Pages 507-514

Suppression of flavin-containing monooxygenase by overproduced nitric oxide in rat liver

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGUANIDINE; BACTERIUM LIPOPOLYSACCHARIDE; CYTOCHROME P450; IMIPRAMINE; MESSENGER RNA; N(G) NITROARGININE; N,N DIMETHYLANILINE; NITRATE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRITE; NITROPRUSSIDE SODIUM; THIOBENZAMIDE; TRIMETHYLAMINE; UNSPECIFIC MONOOXYGENASE;

EID: 0032876068     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.56.3.507     Document Type: Article
Times cited : (20)

References (38)
  • 2
    • 0024573303 scopus 로고
    • An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro
    • Billiar TR, Curran RD, Stuehr DJ, West MA, Bentz BG and Simmons RL (1989) An L-arginine-dependent mechanism mediates Kupffer cell inhibition of hepatocyte protein synthesis in vitro. J Exp Med 169:1467-1472.
    • (1989) J Exp Med , vol.169 , pp. 1467-1472
    • Billiar, T.R.1    Curran, R.D.2    Stuehr, D.J.3    West, M.A.4    Bentz, B.G.5    Simmons, R.L.6
  • 3
    • 0017087792 scopus 로고
    • Cytochrome P-450 heme and the regulation of hepatic heme oxygenase activity
    • Bissell DM and Hammaker LE (1976a) Cytochrome P-450 heme and the regulation of hepatic heme oxygenase activity. Arch Biochem Biophys 176:91-102.
    • (1976) Arch Biochem Biophys , vol.176 , pp. 91-102
    • Bissell, D.M.1    Hammaker, L.E.2
  • 4
    • 0017077407 scopus 로고
    • Cytochrome P-450 heme and the regulation of δ-aminolevulinic acid synthetase in the liver
    • Bissell DM and Hammaker LE (1976b) Cytochrome P-450 heme and the regulation of δ-aminolevulinic acid synthetase in the liver. Arch Biochem Biophys 176:103-112.
    • (1976) Arch Biochem Biophys , vol.176 , pp. 103-112
    • Bissell, D.M.1    Hammaker, L.E.2
  • 5
    • 0028945438 scopus 로고
    • Structural and catalytic properties of the mammalian flavin-containing monooxygenase
    • Cashman JR (1995) Structural and catalytic properties of the mammalian flavin-containing monooxygenase. Chem Res Toxicol 8:165-181.
    • (1995) Chem Res Toxicol , vol.8 , pp. 165-181
    • Cashman, J.R.1
  • 6
    • 0019424957 scopus 로고
    • Microsomal oxidation of thiobenzamide. A photometric assay for the flavin-containing monooxygenase
    • Cashman JR and Hanzlik RP (1981) Microsomal oxidation of thiobenzamide. A photometric assay for the flavin-containing monooxygenase Biochem Biophys Res Commun. 98:147-153
    • (1981) Biochem Biophys Res Commun. , vol.98 , pp. 147-153
    • Cashman, J.R.1    Hanzlik, R.P.2
  • 7
    • 0018190964 scopus 로고
    • Altered theophylline pharmacokinetics during acute respiratory viral illness
    • Chang KC, Bell TD, Lauer BA and Chai H (1978) Altered theophylline pharmacokinetics during acute respiratory viral illness. Lancet 1:1132-1133.
    • (1978) Lancet , vol.1 , pp. 1132-1133
    • Chang, K.C.1    Bell, T.D.2    Lauer, B.A.3    Chai, H.4
  • 8
    • 0028142608 scopus 로고
    • The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs
    • Chung WG and Buhler DR (1994) The effect of spironolactone treatment on the cytochrome P450-mediated metabolism of the pyrrolizidine alkaloid senecionine by hepatic microsomes from rats and guinea pigs. Toxicol Appl Pharmacol 27:314-319.
    • (1994) Toxicol Appl Pharmacol , vol.27 , pp. 314-319
    • Chung, W.G.1    Buhler, D.R.2
  • 9
    • 0031587925 scopus 로고    scopus 로고
    • Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes
    • Chung WG and Cha YN (1997) Oxidation of caffeine to theobromine and theophylline is catalyzed primarily by flavin-containing monooxygenase in liver microsomes. Biochem Biophys Res Commun 235:685-688.
    • (1997) Biochem Biophys Res Commun , vol.235 , pp. 685-688
    • Chung, W.G.1    Cha, Y.N.2
  • 10
    • 0031840976 scopus 로고    scopus 로고
    • Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP1A2 and flavin-containing monooxygenase in N-demethylation of caffeine: Identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns
    • Chung WG, Roh HK, Kim HM and Cha YN (1998) Involvement of CYP3A1, 2B1, and 2E1 in C-8 hydroxylation and CYP1A2 and flavin-containing monooxygenase in N-demethylation of caffeine: Identified by using inducer treated rat liver microsomes that are characterized with testosterone metabolic patterns. Chem-Biol Interact 113:1-14.
    • (1998) Chem-Biol Interact , vol.113 , pp. 1-14
    • Chung, W.G.1    Roh, H.K.2    Kim, H.M.3    Cha, Y.N.4
  • 11
    • 0024365898 scopus 로고
    • Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells
    • Curran RD, Billiar TR, Stuehr DJ, Hofmann K and Simmons RL (1989) Hepatocytes produce nitrogen oxides from L-arginine in response to inflammatory products of Kupffer cells. J Exp Med 170:1769-1774.
    • (1989) J Exp Med , vol.170 , pp. 1769-1774
    • Curran, R.D.1    Billiar, T.R.2    Stuehr, D.J.3    Hofmann, K.4    Simmons, R.L.5
  • 13
    • 0022512717 scopus 로고
    • Recombinant tumor necrosis factor depresses cytochrome P450-dependent microsomal drug metabolism in mice
    • Ghezzi P, Saccardo B and Bianchi M (1986) Recombinant tumor necrosis factor depresses cytochrome P450-dependent microsomal drug metabolism in mice. Biochem Biophys Res Commun 136:316-321.
    • (1986) Biochem Biophys Res Commun , vol.136 , pp. 316-321
    • Ghezzi, P.1    Saccardo, B.2    Bianchi, M.3
  • 15
    • 0029552610 scopus 로고
    • The role of nitric oxide generation in interferonevoked cytochrome P450 down-regulation
    • Hodgson PD and Renton KW (1995) The role of nitric oxide generation in interferonevoked cytochrome P450 down-regulation. Int J Immunopharmacol 17:995-1000.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 995-1000
    • Hodgson, P.D.1    Renton, K.W.2
  • 16
    • 0027300958 scopus 로고
    • Rat liver flavin-containing monooxygenase (FMO): cDNA cloning and expression in yeast
    • Itoh K, Kimura T, Yokoi T, Itoh S and Kamataki T (1993) Rat liver flavin-containing monooxygenase (FMO): cDNA cloning and expression in yeast. Biochim Biophys Acta 1173:165-171.
    • (1993) Biochim Biophys Acta , vol.1173 , pp. 165-171
    • Itoh, K.1    Kimura, T.2    Yokoi, T.3    Itoh, S.4    Kamataki, T.5
  • 17
    • 0027423004 scopus 로고
    • Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants
    • Khatsenko OG, Gross SS, Rifkind AB and Vane JR (1993) Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants. Proc Natl Acad Sci USA 90:11147-11151.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11147-11151
    • Khatsenko, O.G.1    Gross, S.S.2    Rifkind, A.B.3    Vane, J.R.4
  • 18
    • 0030989836 scopus 로고    scopus 로고
    • Nitric oxide differentially affects constitutive cytochrome P450 isoforms in rat liver
    • Khatsenko OG and Kikkawa Y (1997) Nitric oxide differentially affects constitutive cytochrome P450 isoforms in rat liver. J Pharmacol Exp Ther 280:1463-1470.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1463-1470
    • Khatsenko, O.G.1    Kikkawa, Y.2
  • 21
    • 0025181827 scopus 로고
    • Evidence for the presence of distinct flavin-containing monooxygenases in human tissue
    • Lemoine A, Johann M and Cresteil T (1990) Evidence for the presence of distinct flavin-containing monooxygenases in human tissue. Arch Biochem Biophys 276: 336-342.
    • (1990) Arch Biochem Biophys , vol.276 , pp. 336-342
    • Lemoine, A.1    Johann, M.2    Cresteil, T.3
  • 23
    • 0022555433 scopus 로고
    • The pharmacology and toxicology of the interferons: An overview
    • Mannering GL and Deloria LB (1986) The pharmacology and toxicology of the interferons: An overview. Annu Rev Pharmacol Toxicol 26:455-515.
    • (1986) Annu Rev Pharmacol Toxicol , vol.26 , pp. 455-515
    • Mannering, G.L.1    Deloria, L.B.2
  • 25
    • 0029962068 scopus 로고    scopus 로고
    • Suppression of cytochrome P450- and UDP glucuronosyl trasferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes
    • Monshouwer M, Witkamp RF, Nijmeijer SM, Van Amsterdam JG and Van Miert AS (1996) Suppression of cytochrome P450- and UDP glucuronosyl trasferase-dependent enzyme activities by proinflammatory cytokines and possible role of nitric oxide in primary cultures of pig hepatocytes. Toxicol Appl Pharmacol 137: 237-244.
    • (1996) Toxicol Appl Pharmacol , vol.137 , pp. 237-244
    • Monshouwer, M.1    Witkamp, R.F.2    Nijmeijer, S.M.3    Van Amsterdam, J.G.4    Van Miert, A.S.5
  • 26
    • 0029046327 scopus 로고
    • Pretranslational down-regulation of cytochromes P450 2C11 and 3A2 in male rat liver by tumor necrosis factor α
    • Nadin L, Butler AM, Farrell GC and Murray M (1995) Pretranslational down-regulation of cytochromes P450 2C11 and 3A2 in male rat liver by tumor necrosis factor α. Gastroenterology 109:198-205.
    • (1995) Gastroenterology , vol.109 , pp. 198-205
    • Nadin, L.1    Butler, A.M.2    Farrell, G.C.3    Murray, M.4
  • 28
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C (1992) Nitric oxide as a secretory product of mammalian cells. FASEB J 6:3051-3064.
    • (1992) FASEB J , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 29
    • 0026034432 scopus 로고
    • Role of nitric oxide synthesis in macrophage antimicrobial activity
    • Nathan CF and Hibbs JR JB (1991) Role of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol 3:65-70.
    • (1991) Curr Opin Immunol , vol.3 , pp. 65-70
    • Nathan, C.F.1    Hibbs J.B., Jr.2
  • 30
    • 0027244724 scopus 로고
    • Inflammation, immunoregulation, and inducible nitric oxide synthase
    • Nussler AK and Billiar TR (1993) Inflammation, immunoregulation, and inducible nitric oxide synthase. J Leukocyte Biol 64:171-178.
    • (1993) J Leukocyte Biol , vol.64 , pp. 171-178
    • Nussler, A.K.1    Billiar, T.R.2
  • 31
    • 0026613054 scopus 로고
    • Endotoxin and TNF alpha directly stimulate nitric oxide formation in cultured rat hepatocytes from chronically endotoxemic rats
    • Pittner RA and Spitzer JA (1992) Endotoxin and TNF alpha directly stimulate nitric oxide formation in cultured rat hepatocytes from chronically endotoxemic rats. Biochem Biophys Res Commun 185:430-435.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 430-435
    • Pittner, R.A.1    Spitzer, J.A.2
  • 32
    • 0031871085 scopus 로고    scopus 로고
    • Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene
    • Sewer MB, Barclay TB and Morgan ET (1998) Down-regulation of cytochrome P450 mRNAs and proteins in mice lacking a functional NOS2 gene. Mol Pharmacol 54:273-279.
    • (1998) Mol Pharmacol , vol.54 , pp. 273-279
    • Sewer, M.B.1    Barclay, T.B.2    Morgan, E.T.3
  • 33
    • 0030853767 scopus 로고    scopus 로고
    • Nitric oxide independent suppression of P-450 2C11 expression by interleukin-1β and endotoxin in primary rat hepatocytes
    • Sewer MB and Morgan ET (1997) Nitric oxide independent suppression of P-450 2C11 expression by interleukin-1β and endotoxin in primary rat hepatocytes. Biochem Pharmacol 54:729-737.
    • (1997) Biochem Pharmacol , vol.54 , pp. 729-737
    • Sewer, M.B.1    Morgan, E.T.2
  • 34
    • 0032463961 scopus 로고    scopus 로고
    • Down-regulation of the expression of three major rat liver cytochrome P450s by endotoxin in vivo occurs independently of NO production
    • Sewer MB and Morgan ET (1998) Down-regulation of the expression of three major rat liver cytochrome P450s by endotoxin in vivo occurs independently of NO production. J Pharmacol Exp Ther 287:352-358.
    • (1998) J Pharmacol Exp Ther , vol.287 , pp. 352-358
    • Sewer, M.B.1    Morgan, E.T.2
  • 36
    • 0024546562 scopus 로고
    • N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: The role of flavin-containing monooxygenase
    • Stefek M, Benes L and Zelnik V (1989) N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: The role of flavin-containing monooxygenase. Xenobiotica 19:143-150.
    • (1989) Xenobiotica , vol.19 , pp. 143-150
    • Stefek, M.1    Benes, L.2    Zelnik, V.3
  • 38
    • 0023894686 scopus 로고
    • Flavin-containing monooxygenases: Catalytic mechanism and substrate specificities
    • Ziegler DM (1988) Flavin-containing monooxygenases: Catalytic mechanism and substrate specificities. Drug Metab Rev 19:1-32.
    • (1988) Drug Metab Rev , vol.19 , pp. 1-32
    • Ziegler, D.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.