L-2,5-dihydrophenylalanine, an inducer of cathepsin-dependent apoptosis in human promyelocytic leukemia cells (HL-60)

Journal of Antibiotics

Volumn 54, Issue 10, 2001, Pages 810-817

  Kiso, T ^a   Usuki, Y ^a   Ping, X ^a   Fujita, K I ^a   Taniguchi, M ^a  

^a Osaka Prefecture University   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

9 (2,3 DIHYDROXYPROPYL)ADENINE; ALOXISTATIN; CA 074; CALPAIN; CALPASTATIN; CASPASE 3; CASPASE INHIBITOR; CATHEPSIN; CATHEPSIN B; CATHEPSIN L; CATHEPSIN L INHIBITOR; DNA; DNA FRAGMENT; ENZYME INHIBITOR; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOCHEMISTRY; CELL NUCLEUS; CELL PROTECTION; CELL STRUCTURE; CHROMATIN CONDENSATION; ENZYME ACTIVATION; EVIDENCE BASED MEDICINE; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA;

EID: 0035168186     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.54.810     Document Type: Article

References (42)

1. L-1,4-Cyclohexadiene-1-alanine, an antagonist of phenylalanine from Streptomyces
2. 2,5-Dihydrophenylalanine as an inhibitor of microbial growth
3. A tryptophan hydroxylase inhibitor produced by a Streptomycete: 2,5-dihydro-L-phenylalanine
4. 2,5-Dihydro-L-phenylalanine: A competitive inhibitor of indoleamine 2,3-dioxygenase
5. 2]Phenylalanine, an alternate substrate for rat liver phenylalanine hydroxylase
6. Phenylalanine ammonia-lyase: Enzymic conversion of 3-(1,4-cyclohexadienyl)-L-alanine to trans-3-(1,4-cyclohexadienyl) acrylic acid
7. 1,4-Cyclohexadiene-1-alanine (2,5-dihydrophenylalanine) a new inhibitor of phenylalanine for the rat and Leuconostoc dextranicum 8086
8. Lysosomal cysteine proteases: More than scavengers
9. Cloning and expression of mouse legumain, a lysosomal endopeptidase
10. Napsins: New human aspartic proteinases
11. Cathepsin A/protective protein: An unusual lysosomal multifunctional protein
12. Participation of cathepsins B and D in apoptosis of PC12 cells following serum deprivation
13. Cathepsin B contributes to TNF-α-mediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
14. Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes
15. Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity
16. Caspase 3 activation by lysosomal enzymes in cytochrome c-independent apoptosis in myelodysplastic syndrome-derived cell line P39
17. Participation of a cathepsin L-type protease in the activation of caspase 3
18. L-1,4-Cyclohexadiene-1-alanine, an antimetabolite of L-phenylalanine produced by a Pseudomonas
19. 3H]-thymidine incorporation assay
20. Identification of an endonuclease responsible for apoptosis in rat thymocytes
21. Intestinal epithelial cells use two distinct pathways for HLA class II antigen processing
22. Probing the specificity of cysteine proteinases at subsites remote from the active site: Analysis of P4, P3, P2′ and P3′ variations in extended substrates
23. Treating phenylketonuria by a phenylalanine-free diet
24. Tyrosine supplementation for phenylketonuria
25. The mechanism of cycloheximide inhibition of protein synthesis in rabbit reticulocytes
26. Effect of anisomycin on the cellular level of native ribosomal subunits
27. Necessity of detergent for efficient puromycin-mediated release of nascent peptides from rat liver ribosomes
28. Comparative study of the effect of ochratoxin A analogues on yeast aminoacyl-tRNA synthetases and on the growth and protein synthesis of hepatoma cells
29. Two pathways for the induction of apoptosis in human lymphocytes
30. Cobalt prevents nitric oxide-induced apoptotic motoneuron death in vitro
31. An association between mitochondrial function and all-trans retinoic acid-induced apoptosis in acute myeloblastic leukaemia cells
32. Resistance to growth inhibitory and apoptotic effects of phorbol ester and UCN-01 in aggressive cancer cell lines
33. Cells in cryptophycin-induced cell-cycle arrest are susceptible to apoptosis
34. The catalytic DNA topoisomerase II inhibitor dexrazoxane (ICRF-187) induces differentiation and apoptosis in human leukemia K562 cells
35. Inhibition of human caspases by peptide-based and macromolecular inhibitors
36. In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64
37. Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine
38. CA074 methyl ester: A proinhibitor for intracellular cathepsin B
39. The affinity-labelling of cathepsin S with peptidyl diazomethyl ketones. Comparison with the inhibition of cathepsin L and calpain
40. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
41. Differentiating agents regulate cathepsin B gene expression in HL-60 cells
42. Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid