Achieving plant disease resistance by antibody expression

Canadian Journal of Plant Pathology

Volumn 23, Issue 3, 2001, Pages 236-245

  Fischer, Rainer ^a   Emans, Neil ^a   Schillberg, Stefan ^b  

^a Institut Umweltchemie und Ökotoxikologie   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Antibody expression; Genetic engineering; Molecular biotechnology; Pathogen resistant crops; Transgenic plants

Indexed keywords

ANTIBODY ENGINEERING; DISEASE RESISTANCE; GENE TECHNOLOGY; PLANT BIOTECHNOLOGY; PLANT BREEDING; PLANT DISEASE CONTROL; PLANT DISEASE; RECOMBINANT ANTIBODY;

EID: 0035165334     PISSN: 07060661     EISSN: None     Source Type: Journal    
DOI: 10.1080/07060660109506936     Document Type: Review

References (90)

1. Recombination in RNA viruses and in virus-resistant transgenic plants
2. Expression of a single-chain Fv antibody against abscisic acid creates a wilty phenotype in transgenic tobacco
3. Potato tubers as a biofactory for recombinant antibodies
4. RNA as a target and an initiator of post-transcriptional gene silencing in transgenic plants
5. Expression in tobacco of a functional monoclonal antibody specific to stylet secretions of the root-knot nematode
6. Mechanisms and applications of pathogen-derived resistance in transgenic plants
7. Coat-protein-mediated resistance to tobacco mosaic virus: Discovery mechanisms and exploitation
8. Control of tobamovirus infections via pathogen-derived resistance
9. "Phytoantibodies" : A general vector for the expression of immunoglobulin domains in transgenic plants
10. Restoration of wild-type virus by double recombination of tombusvirus mutants with a host transgene
11. Bacterial and plant-produced scFv proteins have similar antigen-binding properties
12. Combined intra- and extracellular immunization against human immunodeficiency virus type 1 infection with a human anti-gp120 antibody
13. Particle gun-mediated transformation
14. Strategies for variety-independent genetic transformation of important cereals, legumes and woody species utilizing particle bombardment
15. Compartment-specific accumulation of recombinant immunoglobulins in plant cells: An essential tool for antibody production and immunomodulation of physiological functions and pathogen activity
16. A ribozyme gene and an antisense gene are equally effective in conferring resistance to tobacco mosaic virus on transgenic tobacco
17. High level accumulation of single-chain variable fragments in the cytosol of transgenic Petunia hybrida
18. Assembly of an antibody and its derived antibody fragment in Nicotiana and Arabidopsis
19. Intact antigen-binding MAK33 antibody and Fab fragment accumulate in intercellular spaces of Arabidopsis thaliana
20. Induction of micronuclei with ochratoxin A in ovine seminal vesicle cell cultures
21. Mycotoxins in plant pathogenesis
22. Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody
23. Synthesis and self-assembly of a functional monoclonal antibody in transgenic Nicotiana tabacum
24. RPE, a plant gene involved in early developmental steps of nematode feeding cells
25. Expression of single-chain antibody fragments (scFv) specific for beet necrotic yellow vein virus coat protein or 25 kDa protein in Escherichia coli and Nicotiana benthamiana
26. Monoclonal antibodies to T-2 toxin - in vitro neutralization of protein synthesis inhibition and protection of rats against lethal toxemia
27. Optimisation of scFv antibody production in transgenic plants
28. Secretion of a functional single-chain Fv protein in transgenic tobacco plants and cell suspension cultures
29. Expression and characterization of bispecific single chain Fv fragments produced in transgenic plants
30. Modulation of plant function and plant pathogens by antibody expression
31. Expression of bacterial genes in plant cells
32. Production of polyclonal and monoclonal antibodies against hyphae from arbuscular mycorrhizal fungi
33. Recombination between viral RNA and transgenic plant transcripts
34. In vitro selection and evolution of functional proteins by using ribosome display
35. Ribosome display efficiently selects and evolves high-affinity antibodies in vitro from immune libraries
36. Selection of phage antibodies by binding affinity. Mimicking affinity maturation
37. Production of antibodies in transgenic plants
38. Efficient transformation of rice (Oryza sativa L.) mediated by Agrobacterium and sequence analysis of the boundaries of the T-DNA
39. Transformation of rice mediated by Agrobacterium tumefaciens
40. Designing and optimising library selection strategies for generating high-affinity antibodies
41. By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro
42. Multi-subunit proteins on the surface of filamentous phage: Methodologies for displaying antibody (Fab) heavy and light chains
43. Building antibodies from their genes
44. A simple and general method for transferring genes into plants
45. Preparation and characterization of monoclonal antibodies to the trichothecene mycotoxin T2
46. An Agrobacterium mediated transient gene expression system for intact leaves
47. Continuous cultures of fused cells secreting antibody of predefined specificity
48. Ribozyme mediated targeting of cucumber mosaic virus RNA 1 and 2 in transgenic tobacco plants
49. Crop diseases and catastrophes
50. Engineering of a single-chain variable-fragment (scFv) antibody specific for the stolbur phytoplasma (Mollicute) and its expression in Escherichia coli and tobacco plants
51. Reconstitution of a functional red clover mosaic virus by recombinational rescue of the cell-to-cell movement gene expressed in a transgenic plant
52. Pathogen-derived resistance to plant viruses
53. Expression and characterisation of single-chain antibody fragments produced in transgenic plants against the organic herbicides atrazine and paraquat
54. Assembly of monoclonal antibodies with IgG1 and IgA heavy chain domains in transgenic tobacco plants
55. Generation and assembly of secretory antibodies in plants
56. By-passing immunization: Building high affinity human antibodies by chain shuffling
57. Phage antibodies: Filamentous phage displaying antibody variable domains
58. Rapid production of specific vaccines for lymphoma by expression of the tumor-derived single-chain Fv epitopes in tobacco plants
59. Expression of a cDNA encoding Phytolacca insularis antiviral protein confers virus resistance on transgenic potato plants
60. Production and characterization of monoclonal antibodies to cell wall components of the flax rust fungus
61. Synthesis of a functional anti-phytochrome single-chain Fv protein in transgenic tobacco
62. Monoclonal antibodies which show restricted binding to four Colletotrichum species: C. lindemuthianum C. malvarum, C. orbiculare and C. trifolii
63. Seed-specific immunomodulation of abscisic acid activity induces a developmental switch
64. Principal diseases of food crops
65. Molecular differentiation in the extrahaustorial membrane of pea powdery mildew haustoria at early and late stages of development
66. Isolation of a cDNA encoding a beta-1,4-endoglucanase in the root-knot nematode Meloidogyne incognita and expression analysis during plant parasitism
67. Recombination with host transgenes and effects on virus evolution: An overview and opinion
68. Efficient in vitro affinity maturation of phage antibodies using BIAcore guided selections
69. Plasma membrane display of anti-viral single chain Fv fragments confers resistance to tobacco mosaic virus
70. The C-terminal KDEL sequence increases the expression level of a single-chain antibody designed to be targeted to both cytosol and the secretory pathway in transgenic tobacco
71. Improving scFv antibody expression levels in the plant cytosol
72. Expression of a functional single-chain antibody against GA(24/19) in transgenic tobacco
73. Endogenous cellulases in animals - Isolation of beta-1,4-endoglucanase genes from two species of plant-parasitic cyst nematodes
74. Expression of antibody fusion proteins in the cytoplasm and ER of plant cells
75. Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from vires attack
76. C-terminal deletion mutant of pokeweed antiviral protein inhibits viral infection but does not depurinate host ribosomes
77. The impacts of the southern corn leaf blight epidemics of 1970-1971
78. Coordinate expression of antibody subunit genes yields high levels of functional antibodies in roots of transgenic tobacco
79. Expression and assembly of a full-length monoclonal antibody in plants using a plant virus vector
80. Reduced vires infectivity in N. tabacum secreting a TMV-specific full size antibody
81. Resistance against multiple plant viruses in plants mediated by a double stranded-RNA specific ribonuclease
82. Pectase lyase of Colletotrichum gloeospoprioides attacking avocado fruits: cDNA cloning and involvement in pathogenicity
83. The use of Ti-plasmids as plant-directed gene vectors
84. Strategies to protect crop plants against viruses: Pathogen-derived resistance blossoms
85. Man-made antibodies
86. Making antibodies by phage display technology
87. Correlation between in vitro stability and in vivo performance of anti- GCN4 intrabodies as cytoplasmic inhibitors
88. A humanized monoclonal antibody produced in transgenic plants for immunoprotection of the vagina against genital herpes
89. Intracellular expression of TMV-specific single-chain Fv fragments leads to improved virus resistance in Nicotiana tabacum