Transcriptional regulation of furA and katG upon oxidative stress in Mycobacterium smegmatis

Journal of Bacteriology

Volumn 183, Issue 23, 2001, Pages 6801-6806

  Milano, A ^a   Forti, F ^a   Sala, C ^a   Riccardi, G ^a   Ghisotti, D ^a  

^a U di Milano   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL DNA; BACTERIAL PROTEIN; KATG PROTEIN; PROTEIN FURA; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; CONTROLLED STUDY; DNA FLANKING REGION; DNA SEQUENCE; GENE ACTIVITY; GENE LOCATION; GENE MAPPING; GENETIC ORGANIZATION; GENETIC TRANSCRIPTION; MOLECULAR CLONING; MYCOBACTERIUM SMEGMATIS; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STREPTOMYCETACEAE; TRANSCRIPTION REGULATION;

BACTERIAL PROTEINS; BASE SEQUENCE; CLONING, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM SMEGMATIS; OXIDATIVE STRESS; PEROXIDASES; PROMOTER REGIONS (GENETICS); REPRESSOR PROTEINS; TRANSCRIPTION, GENETIC;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; STREPTOMYCETACEAE; STREPTOMYCINEAE; UNCULTURED ACTINOMYCETE;

EID: 0035164513     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.23.6801-6806.2001     Document Type: Article

References (35)

1. Mechanisms of phagocytosis in macrophages
2. Molecular mechanism of regulation of siderophore-mediated iron assimilation
3. XL1-Blue: A high efficiency plasmid transforming recA E. coli strain with β-galactosidase selection
4. Positive control of a regulon for defences against oxidative stress and some heat-shock protein in Salmonella typhimurium
5. Bacteriophage P4 immunity controlled by small RNAs via transcription termination
6. Loss of oxyR in Mycobacterium tuberculosis
7. Tropist3: A cosmid vector for simplified mapping of both G+C-rich and A+T-rich genomic DNA
8. Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: Characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis
9. Interdependence of mycobacterial iron regulation, oxidative-stress response and isoniazid resistance
10. Opening the iron box: Transcriptional metalloregulation by the Fur protein
11. The application of luciferase as a reporter of environmental regulation of gene expression in mycobacteria
12. Selective stimulation of translation of leaderless mRNA by initiation factor 2: Evolutionary implications for translation
13. Regulation of the furA and catC operon, encoding a ferric uptake regulator homologue and catalase-peroxidase, respectively, in Streptomyces coelicolor A3(2)
14. Characterization of the katG gene encoding a catalase-peroxidase required for the isoniazid susceptibility of Mycobacterium tuberculosis
15. In Staphylococcus aureus, Fur is an interactive regulator with PerR, contributes to virulence, and is necessary for oxidative stress resistance through positive regulation of catalase and iron homeostasis
16. Eubacterial, archaebacterial, and eukaryotic genes that encode leaderless mRNA
17. Expression of katG in Mycobacterium tuberculosis is associated with its growth and persistence in mice and guinea pigs
18. Enhanced hydrogen peroxide sensitivity and altered stress protein expression in iron-starved Mycobacterium smegmatis
19. Mapping of Mycobacterium tuberculosis katG promoters and their differential expression in infected macrophages
20. The Mycobacterium tuberculosis katG promoter region contains a novel upstream activator
21. The DNA-binding characteristics of the Streptomyces reticuli regulator FurS depend on the redox state of its cysteine residues
22. Oxidative stress response and characterization of the oxyR-ahpC and furA-katG loci in Mycobacterium marinum
23. In vitro insertional mutagenesis with a selectable DNA fragment
24. Regulation of bacterial responses to oxidative stress
25. Control of transcription termination by an RNA factor in bacteriophage P4 immunity: Identification of the target sites
26. Disparate responses to oxidative stress in saprophytic and pathogenic mycobacteria
27. Escherichia coli-mycobacteria shuttle vectors for operon and gene fusions to lacZ: The pJEM series
28. Lethal oxidative damage and mutagenesis are generated by iron in Δfur mutants of Escherichia coli: Protective role of superoxide dismutase
29. Mycobacterial FurA is a negative regulator of catalase-peroxidase gene katG
30. The catalase-peroxidase gene and isoniazid resistance of Mycobacterium tuberculosis
31. Molecular basis for the exquisite sensitivity of Mycobactenum tuberculosis to isoniazid
32. Redox sensing by prokaryotic transcription factors
33. The mycelium-associated Streptomyces reticuli catalase-peroxidase, its gene and regulation by FurS