Successful treatment of patients with rheumatic disorders and acquired factor VIII inhibitors with cyclophosphamide and prednisolone combination therapy: Two case reports

Journal of International Medical Research

Volumn 29, Issue 5, 2001, Pages 432-436

  Nishino, Y ^a   Ueki, K ^a   Suto, M ^a   Uchiumi, H ^a   Ota, F ^a   Tamura, S ^a   Kaneko, Y ^a   Kuroiwa, T ^a   Tsukada, Y ^a   Maezawa, A ^a   Nojima, Y ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

Cyclophosphamid; Factor VIII inhibitors; Prednisolone; Rheumatoid arthritis; Systemic lupus erythematosus

Indexed keywords

AZATHIOPRINE; BLOOD CLOTTING FACTOR 8 INHIBITOR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; INTERFERON; LOMUSTINE; METHYLPREDNISOLONE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE; VINCRISTINE;

ADULT; ARTICLE; AUTOIMMUNE DISEASE; BLEEDING TENDENCY; BLOOD CLOTTING DISORDER; CASE REPORT; DISEASE ASSOCIATION; FATALITY; FEMALE; HEMOPHILIA; HUMAN; RHEUMATIC DISEASE; RHEUMATOID ARTHRITIS; STEROID THERAPY; SYSTEMIC LUPUS ERYTHEMATOSUS; BLOOD; DRUG COMBINATION; HEMOPHILIA A; PARTIAL THROMBOPLASTIN TIME; TREATMENT OUTCOME;

ADULT; ARTHRITIS, RHEUMATOID; CASE REPORT; CYCLOPHOSPHAMIDE; DRUG THERAPY, COMBINATION; FEMALE; HEMOPHILIA A; HUMAN; LUPUS ERYTHEMATOSUS, SYSTEMIC; MIDDLE AGE; PARTIAL THROMBOPLASTIN TIME; PREDNISOLONE; TREATMENT OUTCOME;

EID: 0035157780     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000102900508     Document Type: Article

References (15)

1. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII
2. Corticosteroid therapy for acquired F VIII:C inhibitors
3. A prospective, randomized trial of prednisone and cyclophosphamide in the treatment of patients with factor VIII autoantibodies
4. Successful treatment of acquired factor VIII inhibitors with cyclosporin
5. Lupus nephritis. Experience with 230 patients in a private practice from 1950 to 1980
6. Combination immunosuppressive therapy after factor VIII infusion for acquired factor VIII inhibitor
7. Anti-idiotypic suppression of autoantibodies to factor VIII (antihaemophilic factor) by high-dose intravenous gamma-globulin
8. Disappearance of antibodies to Factor VIII in a patient with acquired haemophilia and carcinoma of the pancreas during cytotoxic therapy with fluorouracil and CCNU
9. Successful treatment of a patient with postpartum factor VIII inhibitor with recombinant human interferon alpha 2a
10. Successful treatment of a non-haemophilic patient with inhibitor to factor VIII by double-filtration plasmapheresis
11. Acquired haemophilia and rheumatoid arthritis
12. Factor VIII antibodies in rheumatoid arthritis. Effect of cyclophosphamide
13. Successful treatment of acquired hemophilia with oral immunosuppressive therapy
14. Long-lasting remission and successful treatment of acquired factor VIII inhibitors using cyclophosphamide in a patient with systemic lupus erythematosus
15. The Committee on Prognosis Studies in SLE: Derivation of the SLEDAI. A disease activity index for lupus patients