Successful treatment of acquired hemophilia with oral immunosuppressive therapy

Annals of Internal Medicine

Volumn 127, Issue 3, 1997, Pages 206-209

  Shaffer, Linda G ^a,c   Phillips, Martin D ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^c WILFORD HALL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 8; CYCLOPHOSPHAMIDE; PREDNISONE;

ADULT; AGED; ARTICLE; BLEEDING; CLINICAL ARTICLE; FEMALE; HEMOPHILIA; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; TREATMENT OUTCOME;

EID: 0030846488     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-127-3-199708010-00005     Document Type: Article

References (9)

1. Lottenberg R, Kentro TB, Kitchens CS. Acquired hemophilia. A natural history study of 16 patients with factor VIII inhibitors receiving little or no therapy. Arch Intern Med. 1987;147:1077-81.
2. Hoyer LW. The incidence of factor VIII inhibitors in patients with severe hemophilia A. In: Aledort LM, Hoyer LW, Lusher JM, Reisner HM, White GC II, eds. Inhibitors to Coagulation Factors. New York: Plenum Pr; 1995:35-46.
3. Hultin MB. Acquired inhibitors in malignant and nonmalignant disease states. Am J Med. 1991;91:9S-13S.
4. Green D, Lechner K. A survey of 215 non-hemophilic patients with inhibitors to Factor VIII. Thromb Haemost. 1981;45:200-3.
5. Morrison AE, Ludlam CA, Kessler C. Use of porcine factor VIII in the treatment of patients with acquired hemophilia. Blood. 1993;81:1513-20.
6. Lian EC, Larcada AF, Chiu AY. Combination immunosuppressive therapy after factor VIII infusion for acquired factor VIII inhibitor. Ann Intern Med. 1989;110:774-8.
7. Green D, Rademaker AW, Briet E. A prospective, randomized trial of prednisone and cyclophosphamide in the treatment of patients with factor VIII autoantibodies. Thromb Haemost. 1993;70:753-7.
8. Green D. Suppression of an antibody to factor VIII by a combination of factor VIII and cyclophosphamide. Blood. 1971;37:381-7.
9. Herbst KD, Rapaport SI, Kenoyer DG, Stanton W, Feinstein DI. Syndrome of an acquired inhibitor of factor VIII responsive to cyclophosphamide and prednisone. Ann Intern Med. 1981;95:575-8.