Effects of nitric oxide and peroxynitrite on the cytochrome oxidase K(m) for oxygen: Implications for mitochondrial pathology

Biochimica et Biophysica Acta - Bioenergetics

Volumn 1459, Issue 2-3, 2000, Pages 390-396

  Cooper, Chris E ^a   Davies, Nathan A ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

Cytochrome oxidase; K(m); Mitochondria; Nitric oxide; Oxygen; Peroxynitrite

Indexed keywords

CYTOCHROME C OXIDASE; NITRIC OXIDE; OXYGEN; PEROXYNITRITE;

ARTICLE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; HUMAN; MITOCHONDRIAL RESPIRATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL;

ANIMALS; BACTERIA; CELL HYPOXIA; ELECTRON TRANSPORT COMPLEX IV; ENZYME ACTIVATION; HUMANS; MITOCHONDRIA; NITRATES; NITRIC OXIDE; OXYGEN; OXYGEN CONSUMPTION;

EID: 0034663539     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2728(00)00176-6     Document Type: Article

References (67)

1. Kacser H., Burns J.A. The control of flux. Symp. Soc. Exp. Biol. 27:1973;65-104.
2. 19F NMR spectroscopy of perfluorocarbon. Magn. Reson. Med. 29:1993;296-302.
3. Jezzard P., Heineman F., Taylor J., DesPres D., Wen H., Balaban R.S., Turner R. Comparison of EPI gradient-echo contrast changes in cat brain caused by respiratory challenges with direct simultaneous evaluation of cerebral oxygenation via a cranial window. NMR Biomed. 7:1994;35-44.
4. 2, measured by in vivo electron paramagnetic resonance oximetry and magnetic resonance imaging. Free Radic. Biol. Med. 21:1996;25-34.
5. Jöbsis F.F. Non-invasive infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science. 198:1977;1264-1267.
6. Vinogradov S.A., Lo L.W., Jenkins W.T., Evans S.M., Koch C., Wilson D.F. Noninvasive imaging of the distribution in oxygen in tissue in vivo using near-infrared phosphors. Biophys. J. 70:1996;1609-1617.
7. 2 changes in cortex and hippocampus of aging gerbil brain. J. Appl. Physiol. 74:1993;1723-1728.
8. Wittenberg B.A., Wittenberg J.B. Transport of oxygen in muscle. Annu. Rev. Physiol. 51:1989;857-878.
9. 2 and ATP. Am. J. Physiol. 250:1986;C663-C675.
10. James P.E., Grinberg O.Y., Michaels G., Swartz H.M. Intraphagosomal oxygen in stimulated macrophages. J. Cell Physiol. 163:1995;241-247.
11. Wittenberg B.A., Wittenberg J.B. Oxygen pressure gradients in isolated cardiac myocytes. J. Biol. Chem. 260:1985;6548-6554.
12. Bassett J.D.R., Howley E.T. Limiting factors for maximum oxygen uptake and determinants of endurance performance. Med. Sci. Sports. Exerc. 32:2000;70-84.
13. Bergh U., Ekblom B., Astrand P.-E. Maximal oxygen uptake 'classical' versus 'contemporary' viewpoints. Med. Sci. Sports Exerc. 32:2000;85-88.
14. Brown G.C. Control of respiration and ATP synthesis in mammalian mitochondria and cells. Biochem. J. 284:1992;1-13.
15. Brand M.D., Murphy M.P. Control of electron flux through the respiratory chain in mitochondria and cells. Biol. Rev. 62:1987;141-193.
16. Petersen L.C., Nicholls P., Degn H. The effect of energization on the apparent Michaelis-Menten constant for oxygen in mitochondrial respiration. Biochem. J. 142:1974;247-252.
17. Wilson D.F., Rumsey W.L., Green T.J., Vanderkooi J.M. The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration. J. Biol. Chem. 263:1988;2712-2718.
18. Rumsey W.L., Schlosser C., Nuutinen E.M., Robiolio M., Wilson D.F. Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat. J. Biol. Chem. 265:1990;15392-15399.
19. Steinlechner-Maran R., Eberl T., Kunc M., Margreiter R., Gnaiger E. Oxygen dependence of respiration in coupled and uncoupled endothelial cells. Am. J. Physiol. 271:1996;C2053-C2061.
20. Wilson D.F., Owen C.S., Erecinska M. Quantitative dependence of mitochondrial oxidative phosphorylation on oxygen concentration: a mathematical model. Arch. Biochem. Biophys. 195:1979;494-504.
21. Gnaiger E., Steinlechner-Maran R., Mendez G., Eberl T., Margreiter R. Control of mitochondrial and cellular respiration by oxygen. J. Bioenerg. Biomembr. 27:1995;583-596.
22. Wilson D.F., Mokashi A., Chugh D., Vinogradov S., Osanai S., Lahiri S. The primary oxygen sensor of the cat carotid body is cytochrome a3 of the mitochondrial respiratory chain. FEBS Lett. 351:1994;370-374.
23. Wilson D.F., Erecinska M., Drown C., Silver I.A. The oxygen dependence of cellular energy metabolism. Arch. Biochem. Biophys. 195:1979;485-493.
24. Sugano T., Oshino N., Chance B. Mitochondrial functions under hypoxic conditions. The steady states of cytochrome c reduction and of energy metabolism. Biochim. Biophys. Acta. 347:1974;340-358.
25. 3 and their relation to mitochondrial energy state. Biochim. Biophys. Acta. 368:1974;298-310.
26. Bashford C.L., Barlow C.H., Chance B., Haselgrove J. The oxidation-reduction state of cytochrome oxidase in freeze trapped gerbil brains. FEBS Lett. 113:1980;78-80.
27. 2 supply dependence. J. Appl. Physiol. 72:1992;1499-1505.
28. Cooper C.E., Matcher S.J., Wyatt J.S., Cope M., Brown G.C., Nemoto E.M., Delpy D.T. Near infrared spectroscopy of the brain: relevance to cytochrome oxidase bioenergetics. Biochem. Soc. Trans. 22:1994;974-980.
29. A in mammalian cytochrome c oxidase. FEBS Lett. 233:1988;25-30.
30. Cooper C., Sharpe M., Elwell C., Springett R., Penrice J., Tyszczuk L., Amess P., Wyatt J., Quaresima V., Delpy D. The cytochrome oxidase redox state in vivo. Adv. Exp. Med. Biol. 428:1997;449-456.
31. Degn H., Wohlrab H. Measurement of steady-state values of respiration rate and oxidation levels of respiratory pigments at low oxygen techniques: a new technique. Biochim. Biophys. Acta. 245:1971;347-355.
32. 3 redox state. Int. Anesthesiol. Clin. 25:1987;209-230.
33. Hampson N.B., Camporesi E.M., Stolp B.W., Moon R.E., Shook J.E., Griebel J.A., Piantadosi C.A. Cerebral oxygen availability by NIR spectroscopy during transient hypoxia in humans. J. Appl. Physiol. 69:1990;907-913.
34. Matcher S.J., Elwell C.E., Cooper C.E., Cope M., Delpy D.T. Performance comparison of several published tissue near-infrared spectroscopy algorithms. Anal. Biochem. 227:1995;54-68.
35. Cooper C.E., Cope M., Springett R., Amess P., Penrice J., Tyszczuk L., Punwani S., Ordidge R., Wyatt J., Delpy D.T. Use of mitochondrial inhibitors to demonstrate that cytochrome oxidase near-infrared spectroscopy can measure mitochondrial dysfunction non-invasively in the brain. J. Cereb. Blood Flow Metab. 19:1999;27-38.
36. Quaresima V., Springett R., Cope M., Wyatt J.T., Delpy D.T., Ferrari M., Cooper C.E. Oxidation and reduction of cytochrome oxidase in the neonatal brain observed by in vivo near infrared spectroscopy. Biochim. Biophys. Acta. 1366:1998;291-300.
37. Cooper C.E., Delpy D.T., Nemoto E.M. The relationship of oxygen delivery to absolute haemoglobin oxygenation and mitochondrial cytochrome oxidase redox state in the adult brain: a near-infrared spectroscopy study. Biochem. J. 332:1998;627-632.
38. Ferrari M., Giannini I., Carpi A., Fasella P. Non-invasive near infrared spectroscopy of brain in fluorocarbon exchange-transfused rats. Physiol. Chem. Phys. Med. NMR. 5:1983;107-113.
39. 2 dependence of in vivo brain cytochrome redox responses and energy metabolism in bloodless rats. J. Cereb. Blood Flow Metab. 8:1988;163-172.
40. Ferrari M., Williams M.A., Wilson D.A., Thakor N., Traystman R.J., Hanley D.F. Cat brain cytochrome-c-oxidase redox changes induced by hypoxia after blood-fluorocarbon exchange transfusion. Am. J. Physiol. 269:1995;H417-H424.
41. Stingele R., Wagner B., Kameneva M.V., Williams M.A., Wilson D.A., Thakor N.V., Traystman R.J., Hanley D.F. Reduction of cytochrome-c-oxidase copper precedes failing cerebral oxygen utilization in fluorocarbon perfused rats. Am. J. Physiol. 40:1996;H579-H587.
42. Springett R., Newman J., Delpy D.T., Cope M. Oxygen dependency of cerebral CuA redox state during increased oxygen consumption produced by infusion of a mitochondrial uncoupler in newborn piglets. Adv. Exp. Med. Biol. 471:1999;181-188.
43. Brown G.C., Cooper C.E. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal cytochrome oxidase respiration by competing with oxygen at cytochrome oxidase. FEBS Lett. 356:1994;295-298.
44. Cooper C.E., Torres J., Sharpe M.A., Wilson M.T. Nitric oxide ejects electrons from the binuclear centre of cytochrome c oxidase by reacting with oxidised copper: a general mechanism for the interaction of copper proteins with nitric oxide? FEBS Lett. 414:1997;281-284.
45. Torres J., Cooper C.E., Wilson M.T. A common mechanism for the interaction of nitric oxide with the oxidised binuclear centre and oxygen intermediates of cytochrome c oxidase. J. Biol. Chem. 273:1998;8756-8766.
46. Torres J., Cooper C.E., Sharpe M., Wilson M.T. Reactivity of nitric oxide with cytochrome c oxidase: interactions with the binuclear centre and mechanism of inhibition. J. Bioenerg. Biomembr. 30:1998;63-69.
47. Cleeter M.W.J., Cooper J.M., Darley-Usmar V.M., Moncada S., Schapira A.H.V. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases. FEBS Lett. 345:1994;50-54.
48. Schweizer M., Richter C. Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension. Biochem. Biophys. Res. Commun. 204:1994;169-175.
49. Takehara Y., Kanno T., Yoshioka T., Inoue M., Utsumi K. Oxygen-dependent regulation of mitochondrial energy metabolism by nitric oxide. Arch. Biochem. Biophys. 323:1995;27-32.
50. Carr G.J., Ferguson S.J. Nitric oxide formed by nitrite reductase of Paracoccus denitrificans is sufficiently stable to inhibit cytochrome oxidase activity and is reduced by its reductase under aerobic conditions. Biochim. Biophys. Acta. 1017:1989;57-62.
51. Guiffre A., Sarti P., D'Itri E., Buse G., Soulimane T., Brunori M. On the mechanism of inhibition of cytochrome c oxidase by nitric oxide. J. Biol. Chem. 271:1996;33404-33408.
52. Torres J., Darley-Usmar V., Wilson M.T. Inhibition of cytochrome c oxidase in turnover by nitric oxide: mechanism and implications for control of respiration. Biochem. J. 312:1995;169-173.
53. Cooper C.E. Nitric oxide and iron proteins. Biochim. Biophys. Acta. 1411:1999;290-309.
54. Brown G.C. Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase. FEBS Lett. 369:1995;136-139.
55. Brown G.C. Nitric oxide and mitochondrial respiration. Biochim. Biophys. Acta. 1411:1999;351-369.
56. Sharpe M.A., Cooper C.E. Interaction of peroxynitrite with mitochondrial cytochrome oxidase: catalytic production of nitric oxide and irreversible inhibition of enzyme activity. J. Biol. Chem. 273:1998;30961-30972.
57. Bolanos J.P., Peuchen S., Heales S.J.R., Land J.M., Clark J.B. Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J. Neurochem. 63:1994;910-916.
58. Bolanos J.P., Heales S.J.R., Land J.M., Clark J.B. Effect of peroxynitrite on the mitochondrial respiratory-chain - differential susceptibility of neurons and astrocytes in primary culture. J. Neurochem. 64:1995;1965-1972.
59. Almeida A., Heales S.J.R., Bolanos J.P., Medina J.M. Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion. Brain Res. 790:1998;209-216.
60. Stadler J., Billiar T.R., Curran R.D., Stuehr D.J., Ochoa J.B., Simmons R.L. Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes. Am. J. Physiol. 260:1991;C910-C916.
61. Stadler J., Curran R.D., Ochoa J.B., Harbrecht B.G., Hoffman R.A., Simmons R.L., Billiar T.R. Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo. Arch. Surg. 126:1991;186-191.
62. Pearce L.L., Pitt B.R., Peterson J. The peroxynitrite reductase activity of cytochrome c oxidase involves a two-electron redox reaction at the heme a(3)-Cu(B) site. J. Biol. Chem. 274:1999;35763-35767.
63. Schapira A.H.V., Cooper J.M. Inborn and induced defects of the mitochondrial respiratory chain. Biochem. Soc. Trans. 22:1994;996-1001.
64. Morgan-Hughes J.A., Schapira A.H.V., Cooper J.M., Holt I.J., Harding A.E., Clark J.B. The molecular pathology of respiratory-chain dysfunction in human mitochondrial myopathies. Biochim. Biophys. Acta. 1018:1990;217-222.
65. Wharton D.C., Tzagoloff A. Cytochrome oxidase from beef heart mitochondria. Methods Enzymol. 10:1967;245-250.
66. Verkhovsky M.I., Morgan J.E., Puustein A., Wikstrom M. Kinetic trapping of oxygen in cell respiration. Nature. 380:1996;268-270.
67. Riistama S., Puustinen A., Garcia-Horsman A., Iwata S., Michel H., Wikstrom M. Channelling of dioxygen into the respiratory enzyme. Biochim. Biophys. Acta. 1275:1996;1-4.