Disruption of metallothionein expression with antisense oligonucleotides abolishes protection against cadmium cytotoxicity in molluscan hemocytes

Toxicological Sciences

Volumn 59, Issue 1, 2001, Pages 101-107

  Butler, R A ^a,b   Roesijadi, G ^a,c  

^a UNIVERSITY OF MARYLAND CENTER FOR ENVIRONMENTAL SCIENCE   (United States)

^b UNIVERSITY OF MAINE   (United States)

^c FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Antisense; Cadmium; Copper; Hemocyte; Lysosome; Metallothionein; Mollusc; Oligodeoxynucleotide; Oyster; Phosphorothioate; Zinc

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; CADMIUM; CADMIUM CHLORIDE; COPPER; METAL; METALLOTHIONEIN; NEUTRAL RED; OLIGODEOXYNUCLEOTIDE PHOSPHOROTHIOATE; ZINC;

ANIMAL CELL; ARTICLE; BLOOD CELL; CELL ISOLATION; CELL PROTECTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; LYSOSOME MEMBRANE; MARINE ENVIRONMENT; MEMBRANE STABILIZATION; MOLLUSC; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN INDUCTION; TOXICITY TESTING;

ANIMALS; CADMIUM; CELL SURVIVAL; COPPER; ENZYME INDUCTION; HEMOCYTES; LYSOSOMES; METALLOTHIONEIN; NEUTRAL RED; OLIGONUCLEOTIDES, ANTISENSE; OSTREIDAE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; ZINC;

ANIMALIA; MOLLUSCA; OSTREIDAE;

EID: 0035154508     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/59.1.101     Document Type: Article

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