Metallothionein mRNA induction and generation of reactive oxygen species in molluscan hemocytes exposed to cadmium in vitro

Comparative Biochemistry and Physiology - C Pharmacology Toxicology and Endocrinology

Volumn 118, Issue 2, 1997, Pages 171-176

  Roesijadi, G ^a,b   Brubacher, L L ^a   Unger, Michael E ^a,c   Anderson, R S ^a,b  

^a UNIVERSITY OF MARYLAND CENTER FOR ENVIRONMENTAL SCIENCE   (United States)

^b UNIVERSITY OF MARYLAND   (United States)

^c UNIVERSITY OF MARYLAND   (United States)

Author keywords

Cadmium; Hemocyte; Metallothionein; Mollusc; Oyster; Reactive oxygen species

Indexed keywords

CADMIUM CHLORIDE; MESSENGER RNA; METALLOTHIONEIN; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; BLOOD CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENE EXPRESSION; IMMUNOTOXICITY; MOLLUSC; NONHUMAN; OYSTER; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN INDUCTION; RESPIRATORY BURST;

ANIMALS; CADMIUM CHLORIDE; HEMOCYTES; METALLOTHIONEIN; OSTREIDAE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 0031467488     PISSN: 07428413     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0742-8413(97)00085-6     Document Type: Article

References (29)

1. Albrecht, D.; Jungi, T.W. Luminol-enhanced chemiluminescence induced in peripheral blood-derived human phagocytes: Obligatory requirement of myeloperoxidase exocytosis by monocytes. J. Leukoc. Biol. 54:300-306;1993.
2. Anderson, R.S. Modulation of blood cell mediated oxyradical production in aquatic species: Implications and applications. In: Malins, D.C.; Ostrander, G.K. (eds). Aquatic Toxicology: Molecular, Biochemical, and Cellular Perspectives. Boca Raton, FL: Lewis Publishers; 1993:241-265.
3. Anderson, R.S.; Oliver, L.M.; Jacobs, D. Immunotoxicity of cadmium for the eastern oyster (Crassostrea virginica [Gmelin 1791]): Effects on hemocyte chemiluminescence. J. Shellfish Res. 11:31-35;1992.
4. Anderson, R.S.; Paynter, K.T.; Burreson, E.M. Increased reactive oxygen intermediate production by hemocytes withdrawn from Crassostrea virginica infected with Perkinsus marinus. Biol. Bull. 183:476-481;1992.
5. Borghesi, L.A.; Lynes, M.A. Nonprotective effects of extracellular metallothionein. Toxicol. Appl. Pharmacol. 139:6-14; 1996.
6. Cherian, M.G.; Chan, H.M. Biological functions of metallothionein - a review. In: Suzuki, K.T.; Imura, N.; Kimura, M. (eds). Metallothionein III: Biological Roles and Medical Implications. Basel: Birkhäuser Verlag; 1993:87-109.
7. Dalton, T.; Palmiter, R.D.; Andrews, G.K. Transcriptional induction of the mouse metallothionein-I gene in hydrogen peroxide-treated Hepa cells involves a composite major late transcription factor antioxidant response element and metal response promoter elements. Nucleic Acids Res. 22:5016-5023;1994.
8. Davies, K.J.A. Oxidative stress: The paradox of aerobic life. In: Rice-Evans, C.; Halliwell, B.; Lunt, G.G. (eds). Free Radicals and Oxidative Stress: Environment, Drugs and Food Additives. London: Portland Press; 1994:1-31.
9. Fliss, H.; Ménard, M. Oxidant-induced mobilization of zinc from metallothionein. Arch. Biochem. Biophys. 293:195-199;1992.
10. Fliss, H.; Ménard, M.; Desai, M. Hypochlorous acid mobilizes cellular zinc. Can. J. Physiol. Pharmacol. 69:1686-1691;1991.
11. Fuentes, M.E.; Unger, M.E.; Roesijadi, G. Individual variability in the 3′ untranslated region of metallothionein mRNAs in a natural population of the mollusc Crassostrea virginica. Mar. Mol. Biol. Biotech. 3:141-148;1994.
12. Kroncke, K.D.; Fehsel, K.; Schmidt, T.; Zenke, F.T.; Dasting, I.; Wesener, J.R.; Bettermann, H.; Breunig, K.D.; Kolb-Bachofen, V. Nitric oxide destroys zinc-sulfur clusters inducing zinc release from metallothionein and inhibition of the zinc finger-type yeast transcription activator lac9. Biochem. Biophys. Res. Commun. 200:1105-1110;1994.
13. Laurin, D.E.; Klasing, K.C. Roles of synthesis and degradation in the regulation of metallothionein accretion in a chicken macrophage-cell line. Biochem. J. 268:459-463;1990.
14. Leibbrandt, M.E.I.; Koropatnick, J. Activation of human monocytes with LPS induces metallothionein expression and is diminished by zinc. Toxicol. Appl. Pharmacol. 124:72-81; 1994.
15. Leibbrandt, M.E.I.; Koropatnick, J. Antisense down-regulation of metallothionein in a human monocytic line alters adherence, invasion, and the respiratory burst. Cell Growth Differ. 5:17-25;1994.
16. Martoja, M.; Martin, J.-L. Detoxification of cadmium by the oyster Crassostrea gigas (Mollusc, Bivalve). Characterization of a cadmium-binding protein in the zinc and copper-containing amoebocytes. C.R. Acad. Sci. Paris 300:549-554;1985.
17. Mesna, O.J.; Steffensen, I.L.; Hjertholm, H.; Andersen, R.A. Accumulation of metallothionein and its multiple forms by zinc, cadmium and dexamethasone in human peripheral T and B lymphocytes and monocytes. Chem. Biol. Interact. 94: 225-242;1995.
18. Misra, R.R.; Hochadel, J.F.; Smith, G.T.; Cook, J.C.; Waalkes, M.P.; Wink, D.A. Evidence that nitric oxide enhances cadmium toxicity by displacing the metal from metallothionein. Chem. Res. Toxicol. 9:326-330;1996.
19. Olsson, P.-E.; Kling, P.; Erkell, L.J.; Kille, P. Structural and functional analysis of the rainbow trout (Oncorhyncus mykiss) metallothionein-A gene. Eur. J. Biochem. 230:344-349;1995.
20. Pauwels, M.; Vanweyenbergh, J.; Soumillion, A.; Proost, P.; Deley, M. Induction by zinc of specific metallothionein isoforms in human monocytes. Eur. J. Biochem. 220:105-110; 1994.
21. Roesijadi, G.; Hansen, K.M.; Fuentes, M.E. Cadmium induced expression of metallothionein and suppression of RNA to DNA ratios during molluscan development. Toxicol. Appl. Pharmacol. 133:130-138;1995.
22. Roesijadi, G.; Klerks, P. A kinetic analysis of Cd-binding to metallothionein and other intracellular ligands in oyster gills. J. Exp. Zool. 251:1-12;1989.
23. Roesijadi, G.; Vestling, M.M.; Murphy, C.M.; Klerks, P.L.; Fenselau, C. Structure and time-dependent behavior of acetylated and non-acetylated forms of a molluscan metallothionein. Biochim. Biophys. Acta 1074:230-236;1991.
24. Sato, M.; Bremner, I. Oxygen free radicals and metallothionein. Free Radic. Biol. Med. 14:325-337;1993.
25. Scott, A.L.; Klesius, P.H. Chemiluminescence: A novel analysis of phagocytosis in fish. In: Anderson, D.P.; Hennesen, W. (eds). Developments in Biological Standardization. Bäsel: S. Karger; 1981:246-254.
26. Steinert, S.A.; Pickwell, G.V. Expression of heat shock proteins and metallothionein in mussels exposed to heat stress and metal ion challenge. Mar. Environ. Res. 24:211-214; 1988.
27. Stoh, S.J.; Bagchi, D. Oxidative mechanisms in the toxicity of metal ions. Free Radic. Biol. Med. 18:321-336;1995.
28. Thiele, D.J. Metal-regulated transcription in eukaryotes. Nucleic Acids Res. 20:1183-1191;1992.
29. Youn, J.; Borghesi, L.; Olson, E.; Lynes, M. Immunomodulatory effects of extracellular metallothionein (II). Effects on macrophage functions. J. Toxicol. Environ. Health 45:397-413;1995.