Polymeric IgA binding to the human pIgR elicits intracellular signalling, but fails to stimulate pIgR-Transcytosis

Scandinavian Journal of Immunology

Volumn 53, Issue 1, 2001, Pages 56-64

  Giffroy, D ^a   Courtoy, P J ^a   Vaerman, J P ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOLIPASE C; SECRETORY COMPONENT;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN; RABBIT; SECOND MESSENGER; SIGNAL TRANSDUCTION; TRANSCYTOSIS;

ADENOCARCINOMA; ANIMALS; CALCIUM SIGNALING; CELL LINE; DNA, COMPLEMENTARY; DOGS; ENZYME ACTIVATION; HUMANS; IMMUNOGLOBULIN A; INOSITOL 1,4,5-TRISPHOSPHATE; IONOMYCIN; IONOPHORES; KIDNEY TUBULES, PROXIMAL; LUNG NEOPLASMS; PROTEIN KINASE C; PROTEIN TRANSPORT; RABBITS; RATS; RECEPTORS, POLYMERIC IMMUNOGLOBULIN; RECOMBINANT FUSION PROTEINS; SECOND MESSENGER SYSTEMS; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; TETRADECANOYLPHORBOL ACETATE; TRANSFECTION; TUMOR CELLS, CULTURED; VACCINATION;

EID: 0035150687     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2001.00843.x     Document Type: Article

References (49)

1. Epithelial and hepatobiliary transport of polymeric immunoglobulins
2. Transcellular transport of polymeric IgA in the rat hepatocyte: Biochemical and morphological characterization of the transport pathway
3. Polymeric IgA and galactose-specific pathways in rat hepatocytes: Evidence for intracellular ligand sorting
4. Sorting mechanisms regulating membrane traffic in the apical transcytotic pathway of polarized MDCK cells
5. Marker enzymes in rat liver vesicles involved in transcellular transport
6. Receptor-mediated transcytosis of IgA in MDCK cells is via apical recycling endosomes
7. Transepithelial transport of immunoglobulins
8. Regulation of protein traffic in polarized epithelial cells
9. Structure and function of the polymeric immunoglobulin receptor in epithelial cells
10. Intracellular neutralization of HIV transcytosis across tight epithelial barriers by anti-HIV envelope protein dIgA or IgM
11. New insights into epithelial cell function in mucosal immunity: Neutralization of intracellular pathogens and excretion of antigens by IgA
12. Interaction of antigens and antibodies at mucosal surfaces
13. Stimulation of transcytosis of the polymeric immunoglobulin receptor by dimeric IgA
14. Transcytosis of the polymeric Ig receptor requires phosphorylation of serine 664 in the absence but not the presence of dimeric IgA
15. In vivo stimulation of polymeric Ig receptor transcytosis by circulating polymeric IgA in rat liver
16. Role of tyrosine phosphorylation in ligand-induced regulation of transcytosis of the polymeric Ig receptor
17. Phorbol myristate acetate-mediated stimulation of transcytosis and apical recycling in MDCK cells
18. Signal transduction by the polymeric immunoglobulin receptor suggests a role in regulation of receptor transcytosis
19. The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains
20. Molecular cloning of the human transmembrane secretory component and its mRNA expression in human tissues
21. Intracellular targetting signals of polymeric immunoglobulin receptors are highly conserved between species
22. Chromosomal localization and detection of DNA polymorphisms in the bovine polymeric immunoglobulin receptor gene
23. Molecular cloning of the mouse polymeric Ig receptor. Functional regions of the molecule are conserved among five mammalian species
24. Two stages of increased IgA transfer during lactation in the Marsupial, Trichosurus vulpecula (Brushtail Possum)
25. Immunoglobulin transport and the polymeric immunoglobulin receptor
26. Alternate splicing of rabbit polymeric immunoglobulin receptor
27. Human secretory immunoglobulin M. An immunochemical and immunohistochemical study
28. Comparison of human, bovine and rabbit secretory component-immunoglobulin interactions
29. Fine specificity of ligand-binding domain 1 in the polymeric Ig receptor: Importance of the CDR2-containing region for IgM interaction
30. Rat secretory component binds poorly to rodent IgM
31. Hepatic transfer of polymeric IgA from plasma to bile in rats and other mammals: A survey
32. Immunohistochemical localization of secretory component in the liver of guinea pigs and dogs versus rats, rabbits and mice
33. Phylogenetic development and comparative physiology of IgA
34. Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM
35. Reverse transcriptionpolymerase chain reaction (RT-PCR) phenotypic analyses of cell cultures of human tracheal epithelium, tracheobronchial glands, and lung carcinomas
36. Comparative studies of transcytosis and assembly of secretory IgA in Madin-Darby Canine Kidney cells expressing human polymeric Ig receptor
37. Polymeric immunoglobulin receptor expressed in MDCK cells transcytoses IgA
38. Homogeneous IgA monomers, dimers, trimers and tetramers from the same IgA myeloma serum
39. Isolation and characterization of secretory IgA and free secretory component from rat bile
40. Transcytosis of the polymeric immunoglobulin receptor is regulated in multiple intracellular compartments
41. Transduction of basolateral-to-apical signals across epithelial cells: Ligand-stimulated transcytosis of the polymeric immunoglobulin receptor requires two signals
42. Dimerization of the polymeric immunoglobulin receptor controls its transcytotic trafficking
43. Calmodulin binds to the basolateral targeting signal of the polymeric immunoglobulin receptor
44. Free secretory component and lactofetrin of human milk inhibit the adhesion of enterotoxigenic Escherichia coli
45. Secretory immunoglobulin A carries oligosaccharide receptors for Escherichia coli type 1 fimbria lectin
46. Binding of Clostridium difficile toxin A to human milk secretory component
47. SpsA, a novel pneumococcal surface protein with specific binding to secretory immunoglobulin A and secretory component
48. Species specific binding of human secretory component to SpsA protein of Streptococcus pneumoniae via a hexapeptide motif
49. Regulation of the formation and external transport of secretory immunoglobulins