Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diamines

Anticancer Research

Volumn 21, Issue 4 A, 2001, Pages 2835-2839

  Markidis, T ^a   Padron, J M ^a   Martin, V S ^a   Peters, G J ^a   Kokotos, G ^a  

^a UNIVERSITY OF ATHENS   (Greece)

Author keywords

1,2 diamines; 2 amino alcohols; Cytotoxicity; Non natural a amino acids

Indexed keywords

1,2 DIAMINE DERIVATIVE; 2 AMINOALCOHOL DERIVATIVE; AMINOALCOHOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; CYTOTOXICITY; ENANTIOMER; IC 50; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SOLID TUMOR; SYNTHESIS;

AMINO ALCOHOLS; ANIMALS; DIAMINES; DRUG SCREENING ASSAYS, ANTITUMOR; MICE; STEREOISOMERISM; TUMOR CELLS, CULTURED;

EID: 0035149524     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Physiology and pathophysiology of sphingolipid metabolism and signalling
2. Cannabimimetic fatty acid derivatives in cancer and inflammation
3. Inhibition of pancreatic cancer growth by the isoprenoids farnesol and geraniol
4. Chemoprevention of cancer with the monoterpene perillyl alcohol
5. Cytotoxic activity of polyprenyl alcohols and vitamin K
6. Synthesis and in vitro cytotoxicity of lipidic alcohols and amines
7. Synthesis and cytotoxicity of aminosterols: Activity studies on a non-small-cell bronchopulmonary carcinoma line (NSCLC-N6)
8. Synthesis of medicinally useful lipidic α-amino acids, 2-amino alcohols and diamines
9. A general approach to the asymmetric synthesis of unsaturated lipidic α-amino acids. The first synthesis of α-aminoarachidonic acid
10. Enantiospecific synthesis of α-amino acid semialdehydes: A key step for the synthesis of unnatural unsaturated and saturated α-amino acids
11. Synthetic routes to lipidic diamines and amino alcohols: A class of potential antiinflammatory agents
12. Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols
13. Synergistic interaction between cisplatin and gemcitabine in vitro
14. Combination chemotherapy studies with gemcitabine
15. Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines
16. Comparison of the sulforhodamine B protein and tetrazolium (MTT) assays for in vitro chemosensitivity testing
17. New colorimetric cytotoxicity assay for anticancer-drug screening
18. A novel method for the rapid, non-aqueous t-butoxycarbonylation of some (17)O-labeled amino acids and (17)O-N.M.R. parameters of the products
19. Selective one-pot conversion of carboxylic acids into alcohols
20. α-methoxy-α-trifluoromethylphenylacetic acid, a versatile reagent for the determination of enantiomeric composition of alcohols and amines