Slow-release tramadol for treatment of chronic malignant pain - An open multicenter trial

Supportive Care in Cancer

Volumn 9, Issue 1, 2001, Pages 48-54

  Petzke, Frank ^a   Radbruch, Lukas ^a   Sabatowski, Rainer ^a   Karthaus, Marko ^a   Mertens, Annette ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b GRÜNENTHAL GMBH   (Germany)

Author keywords

Cancer pain; Clinical trial; Opioids; Slow release preparations; Tramadol

Indexed keywords

ANALGESIC AGENT; NAPROXEN; OPIATE; TRAMADOL;

ADULT; AGED; ARTICLE; CANCER PAIN; CLINICAL TRIAL; CONSTIPATION; DRUG EFFICACY; DRUG SAFETY; FATIGUE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; NAUSEA AND VOMITING; PRIORITY JOURNAL; SLOW RELEASE FORMULATION; SWEATING; VERTIGO;

ADULT; AGED; ANALGESICS, OPIOID; CHRONIC DISEASE; DELAYED-ACTION PREPARATIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; PAIN; TRAMADOL; TREATMENT OUTCOME;

EID: 0035146691     PISSN: 09414355     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. The clinical use of tramadol hydrochloride
2. Efficacité et tolérance du tramadol dans les douleurs néoplasiques - Étude comparative par rapport au buprénorphine
3. Oral tramadol and buprenorphine in tumor pain. An Italian multicentre trail
4. Tramadol revisited
5. Tolerance and safety of tramadol use. Results from international studies and data from drug surveillance
6. Pharmacology of tramadol
7. A clinical study on the use of codeine, oxycodone, dextropropoxyphene, buprenorphine, pentazocine in cancer pain
8. Randomized evaluation of controlled-release codeine and placebo in chronic cancer pain
9. Morphine in cancer pain: Modes of administration
10. Placebo-blinded study of morphine sulfate sustained-release tablets and immediate-release morphine sulfate solution in outpatients with chronic pain due to advanced cancer
11. The relative toxicity of nonsteroidal anti-inflammatory drugs
12. Tramadol - A weak opioid for relief of cancer pain
13. Prevalence and pattern of symptoms in patients with cancer pain: A prospective evaluation of 1635 cancer patients referred to a pain clinic
14. High-dose tramadol in comparison to low-dose morphine for cancer pain relief
15. Controlled-release morphine (MST Contin) in advanced cancer. The European experience
16. Risks of peptic ulcer associated with individual non-steroidal anti-inflammatory drugs
17. Analgetische Wirkung von Tramadol bei Patienten mit malignen Erkrankungen
18. Behandlung von Tumorschmerzen mit Flupirtin - Ergebnisse eiener Doppelblindstudie versus Tramadol
19. Dextropropoxyphene versus morphine in opioid-naive cancer patients with pain
20. Treatment of pain with sustained-release tramadol 100, 150, 200 mg: Results of a post-marketing surveillance study
21. Analgesic effect of tramadol in cancer patients with chronic pain: A comparison with prolonged-action morphine sulfate
22. Analgesic efficacy and tolerability of tramadol 100 mg sustainedrelease capsules in patients with moderate to severe chronic low back pain
23. A risk-benefit assessment of tramadol in the management of pain
24. The basic science of tramadol hydrochloride
25. Tramadol in cancer pain
26. Can a controlled-release oral dose form of oxycodone be used as readily as an immediate-release form for the purpose of titrating to stable pain control
27. Comparison of the analgesic efficacy and tolerability of tramadol 100 mg sustained-release tablets and tramadol 50 mg capsules for the treatment of chronic low back pain
28. Tramadol hydrochloride in the relief of cancer pain. A double blind comparison against sustained release morphine
29. Prevalence of symptoms among patients with advanced cancer: An international collaborative study
30. A validation study of the WHO method for cancer pain relief
31. A controlled study of sustained-release morphine sulfate tablets in chronic pain from advanced cancer
32. Oral tramadol, a μ-opioid agonist and monoamine reuptake blocker, and morphine for strong cancer-related pain
33. The effect of tramadol and morphine on pain and gastrointestinal motor function in patients with chronic pancreatitis
34. Validation of World Health Organization guidelines for cancer pain relief: A 10-year prospective study