The two RNA ligases of the Trypanosoma brucei RNA editing complex: Cloning the essential band IV gene and identifying the band V gene

Molecular and Cellular Biology

Volumn 21, Issue 4, 2001, Pages 979-989

  Rusche L N ^a   Huang, C E ^a   Piller, K J ^a   Hemann, M ^a   Wirtz, E ^a   Sollner Webb, B ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; MESSENGER RNA; RNA LIGASE;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN PURIFICATION; RNA SPLICING; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; DNA, COMPLEMENTARY; DNA, PROTOZOAN; ESCHERICHIA COLI; GENES, PROTOZOAN; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; RNA EDITING; RNA LIGASE (ATP); RNA, PROTOZOAN; SEQUENCE HOMOLOGY, AMINO ACID; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0035145703     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.4.979-989.2001     Document Type: Article

References (49)

1. Trans splicing of nuclear pre-mRNAs
2. Mechanism and evolution of RNA editing in kinetoplastida
3. The Leishmania kinetoplast-mitochondrion contains terminal uridylyl transferase and RNA ligase activities
4. Isolation and sequence of the tRNA ligase-encoding gene of Candida albicans
5. Multiple nucleotide cofactor use by yeast ligase in tRNA splicing: Evidence for independent ATP- and GTP-binding sites
6. The mitochondrial RNA ligase from L. tarentolae can join RNA molecules bridged by a complementary RNA
7. A model for RNA editing in kinetoplastid mitochondria: "Guide" RNA molecules transcribed from maxicircle DNA provide the edited information
8. Complexes from Trypanosoma brucei that exhibit deletion editing and other editing-associated properties
9. Trypanosome U-deletional RNA editing involves gRNA-directed endonuclease cleavage, terminal U exonuclease, and RNA ligase activities
10. Trypanosoma brucei U insertion and U deletion activities co-purify with an enzymatic editing complex but are differentially optimized
11. Stable transformation of T. brucei that occurs exclusively by homologous recombination
12. cDNA expressed sequence tags of T. brucei rhodesiense provide new insights into the biology of the parasite
13. Uridine insertion/deletion RNA editing in trypanosome mitochondria - A review
14. Mechanism of action of a yeast RNA ligase in tRNA splicing
15. Defining the editing "reaction."
16. Conservation of mitochondrial targeting sequence function in mitochondrial and hydrogenosomal proteins from the early-branching eukaryotes crithidia, trypanosoma and trichomonas
17. A 5′ exoribonuclease and RNA ligase of T. brucei
18. Evolution of parasitism: Kinetoplastid protozoan history reconstructed from mitochondrial rRNA gene sequences
19. Homologous recombination and stable transfection in the parasitic protozoan T. brucei
20. RNA editing: A mechanism for gRNA-specified uridylate insertion into precursor mRNA
21. Mating type switching in yeast is controlled by asymmetrical localization of ASH1 mRNA
22. Human and fungal 3′ splice sites are used by Trypanosoma brucei for trans splicing
23. Phage T4-coded stp: Double edged effector of coupled DNA and tRNA-restriction systems
24. Isolation and characterization of an RNA ligase from HeLa cells
25. Purification of wheat germ RNA ligase II: Mechanism of action of wheat germ RNA ligase
26. Resolution of the RNA editing gRNA-directed endonuclease from two other endonucleases of Trypanosoma brucei mitochondria
27. Control of ribosome biogenesis in yeast
28. Recognition and binding of mitochondrial presequences during the import of proteins into mitochondria
29. Purification of a functional enzymatic editing complex from Trypanosoma brucei mitochondria
30. Guide RNA-mRNA chimeras, which are potential RNA editing intermediates, are formed by endonuclease and RNA ligase in a trypanosome mitochondrial extract
31. RNA ligase and its involvement in guide RNA/mRNA chimera formation: Evidence for a cleavage-ligation mechanism of Trypanosoma brucei mRNA editing
32. Biochemical methods for analysis of kinetoplastid RNA editing
33. Direct visualization of uridylate deletion in vitro suggests a mechanism for kinetoplastid RNA editing
34. RNA editing: Transfer of genetic information from gRNA to precursor mRNA in vitro
35. Mutational analysis of vaccinia DNA ligase defines residues essential for covalent catalysis
36. RNA capping enzyme and DNA ligase: A superfamily of covalent nucleotidyl transferases
37. A guide to RNA editing
38. RNA editing in kinetoplastid protozoa
39. Targeted insertion of the neomycin phosphotransferase gene into the tubulin gene cluster of T. brucei
40. T4 RNA ligase
41. Mitochondrial targeting sequences may form amphiphilic helices
42. Protein sorting signals: Simple peptides with complex functions
43. The economics of ribosome biosynthesis in yeast
44. Novel activity of a yeast ligase deletion polypeptide: Evidence for GTP-dependent tRNA splicing
45. RNA end-labeling and RNA ligase activities can produce a circular rRNA in whole cell extracts from trypanosomes
46. Regulated processive transcription of chromatin by T7 RNA polymerase in T. brucei
47. A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in T. brucei
48. Conserved mechanism of tRNA splicing in eukaryotes