Urinary nandrolone metabolites of endogenous origin in man: A confirmation by output regulation under human chorionic gonadotropin stimulation

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 1, 2001, Pages 146-150

  Reznik, Yves ^a   Dehennin, Louis ^b   Coffin, Christine ^a   Mahoudeau, Jacques ^a   Leymarie, Pierre ^a  

^a CHU CÔTE DE NACRE   (France)

^b Lab Fed Natl Courses Francaises   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANABOLIC AGENT; ANDROSTERONE DERIVATIVE; CHORIONIC GONADOTROPIN; DEOXYGLUCOSE; DRUG METABOLITE; ESTRADIOL; GLUCOSE; HYDROCORTISONE; INSULIN; NANDROLONE; TESTOSTERONE;

ADULT; AROMATIZATION; ARTICLE; ATHLETE; BODY MASS; CLINICAL ARTICLE; FEMALE; GAS CHROMATOGRAPHY; GLUCOSE ASSAY; HORMONAL REGULATION; HORMONE DETERMINATION; HUMAN; HYPOGLYCEMIA; MALE; MASS SPECTROMETRY; MAXIMUM ALLOWABLE CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; RAT; STEROID METABOLISM; STEROID URINE LEVEL; STEROIDOGENESIS; URINARY EXCRETION;

EID: 0035145688     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jcem.86.1.7100     Document Type: Article

References (35)

1. Rising plasma levels of 19-nortestosterone throughout pregnancy: Determination by radioimmunoassay and validation by gas-chromatography mass-spectrometry
2. Detection and quantitation of 19-norandrosterone in urine by isotope dilution-mass-spectrometry
3. Urinary excretion of 19-norandrosterone of endogenous origin in man: Quantitative analysis by gas chromatography-mass spectrometry
4. Evidence for the presence of endogenous 19-norandrosterone in human urine
5. Identification of 19-norandrostenedione in follicular fluid
6. Gas chromatography-mass spectrometry of androgens in equine ovarian follicles at ultrastructurally defined stages of development. Identification of 19-nortestosterone in follicular fluid
7. Androgen and 19-norsteroid profiles in human preovulatory follicles from stimulated cycles: An isotope dilutionmass spectrometry study
8. Synthesis and aromatization of 19-norandrogens in the stallion testis
9. Formation of 4-oestrene-3,17-dione (19-norandrostenedione) by porcine granulosa cells in vitro is inhibited by the aromatase inhibitor 4-hydroxyandrostenedione and the cytochrome P-450 inhibitors aminoglutethimide phosphate and ketoconazole
10. In vitro 19-norandrogen synthesis by equine placenta requires the participation of aromatase
11. Androgen and 19-norandrogen aromatization by equine and human placental microsomes
12. Pharmacokinetics of 19-nortestosterone esters in normal men
13. Pharmacokinetic parameters of nandrolone (19-nortestosterone) after intramuscular administration of nandrolone decanoate (Deaca-Durabolin) to healthy volunteers
14. Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: Effects of ester, injection site and injection volume
15. Determination of urinary norandrosterone excretion in females during one menstrual cycle by GC-MS
16. Effects of acute metabolic stress on plasma progesterone and testosterone in male subjects: Relationship to pituitary-adrenocortical axis activation
17. Glucocorticoid receptors in interstitial cells of rat testis
18. Direct inhibitory effect of glucocorticoids upon testicular luteinizing hormone receptor and steroidogenesis in vivo and in vitro
19. Cortisol suppresses the LH, but not the FSH, response to gonadotropin-releasing hormone after orchidectomy
20. Opioids act centrally to modulate stress-induced decrease in luteinizing hormone in the rat
21. Non-aromatizing androgen C10-19 lyase: Biosynthesis of 19-norandrostenedione by dog adrenal
22. Functional aromatase expression in porcine adrenal gland and testis
23. Aromatase expression in a feminizing adrenocortical tumor
24. Dissociated responses of plasma testosterone and estradiol to human chorionic gonadotropin in adult men
25. Biochemical mechanism of aromatization
26. Aromatization of 19-norandrogens by equine testicular microsomes
27. Kinetics of human chorionic gonadotropin-induced steroidogenic response of the human testis. II. Plasma 17-hydroxyprogesterone, Δ4-androstenedione, estrone, and 17β-estradiol: Evidence for the action of human chorionic gonadotropin on intermediate enzymes implicated in steroid biosynthesis
28. Modulation of Leydig cell androgen biosynthesis and cytochrome P-450 levels during estrogen treatment and human chorionic gonadotropin-induced desensitization
29. Acute stimulation of aromatization in leydig cells by human chorionic gonadotropin in vitro
30. Differential response of luteinizing hormone receptor and steroidogenic enzyme gene expression to human chorionic gonadotropin stimulation in the neonatal and adult rat testis
31. Gonadotropic regulation of aromatase activity in the adult rat testis
32. Aromatization of androstenedione by human adipose tissue stromal cells in monolayer culture
33. Aromatization of androstenedione by cultured human fibroblasts
34. Characterization of aromatase cytochrome P450 activity in the human temporal lobe
35. Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis