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Volumn 281, Issue 1, 1997, Pages 93-102

Pharmacokinetics and pharmacodynamics of nandrolone esters in oil vehicle: Effects of ester, injection site and injection volume

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIS OIL; ESTER; INHIBIN; NANDROLONE DECANOATE; NANDROLONE PHENPROPIONATE; TESTOSTERONE;

EID: 0030924263     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (72)

References (42)
  • 1
    • 0023103839 scopus 로고
    • Influence of solvent on the availability of testosterone propionate from oily, intramuscular injections in the rat
    • AL-HINDAWI, M. K., JAMES, K. C. AND NICHOLLS, P. J.: Influence of solvent on the availability of testosterone propionate from oily, intramuscular injections in the rat. J. Pharm. Pharmacol 39: 90-95, 1986.
    • (1986) J. Pharm. Pharmacol , vol.39 , pp. 90-95
    • Al-Hindawi, M.K.1    James, K.C.2    Nicholls, P.J.3
  • 2
    • 0014263049 scopus 로고
    • Biopharmaceutical considerations in subcutaneous and intramuscular drug administration
    • BALLARD, B. E.: Biopharmaceutical considerations in subcutaneous and intramuscular drug administration. J. Pharm. Sci. 57: 357-378, 1968.
    • (1968) J. Pharm. Sci. , vol.57 , pp. 357-378
    • Ballard, B.E.1
  • 3
    • 8244226230 scopus 로고
    • Prolonged-action pharmaceuticals
    • Mack Publishing Co., Easton, PA
    • BALLARD, B. E.; Prolonged-action pharmaceuticals. In Remingtons Pharmaceutical Sciences, pp. 1594-1613, Mack Publishing Co., Easton, PA, 1980.
    • (1980) Remingtons Pharmaceutical Sciences , pp. 1594-1613
    • Ballard, B.E.1
  • 5
    • 0015070644 scopus 로고
    • Absorption rates of various substances administered intramuscularly
    • BEDBRKA, J., TAKEMORI, A. E. AND MILLER, J. W.: Absorption rates of various substances administered intramuscularly. Eur. J. Pharmacol. 15: 132-136, 1971.
    • (1971) Eur. J. Pharmacol. , vol.15 , pp. 132-136
    • Bedbrka, J.1    Takemori, A.E.2    Miller, J.W.3
  • 6
    • 0026649012 scopus 로고
    • Effective suppression of luteinizing hormone and testosterone by single doses of the new gonadotropin-releasing hormone antagonist Cetrorelix (SB-75) in normal men
    • BEHRE, H. M., KLEIN, B., STEINMEYER, E., MCGREGOR, G. P., VOIGT, K. AND NIESCHLAG, E.: Effective suppression of luteinizing hormone and testosterone by single doses of the new gonadotropin-releasing hormone antagonist Cetrorelix (SB-75) in normal men. J. Clin. Endocrinol. Metab. 75: 393-398, 1992.
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 393-398
    • Behre, H.M.1    Klein, B.2    Steinmeyer, E.3    Mcgregor, G.P.4    Voigt, K.5    Nieschlag, E.6
  • 7
    • 0000915913 scopus 로고
    • Comparative pharmacokinetics of androgen preparations: Application of computer analysis and simulation
    • ed. by E. Nieschlag and H. M. Behre, Springer-Verlag, Berlin
    • BEHRE, H. M., OBERPENNING, F. AND NIESCHLAO, E.: Comparative pharmacokinetics of androgen preparations: Application of computer analysis and simulation. In Testosterone: Action Deficiency Substitution, ed. by E. Nieschlag and H. M. Behre, pp. 115-135, Springer-Verlag, Berlin, 1990.
    • (1990) Testosterone: Action Deficiency Substitution , pp. 115-135
    • Behre, H.M.1    Oberpenning, F.2    Nieschlao, E.3
  • 9
    • 0000575078 scopus 로고
    • A study of oils used for intramuscular injections
    • BROWN, W., WILDER, V. AND SCHWARTZ, P.: A study of oils used for intramuscular injections. J. Lab. Clin. Med. 29: 259-264, 1944.
    • (1944) J. Lab. Clin. Med. , vol.29 , pp. 259-264
    • Brown, W.1    Wilder, V.2    Schwartz, P.3
  • 13
    • 0028145951 scopus 로고
    • Failure of recombinant growth hormone or insulin-like growth factor-I to influence gonadotrophin sensitivity of the non-human primate testis in-vivo
    • CRAWFORD, B. A. AND HANDELSMAN, D. J.: Failure of recombinant growth hormone or insulin-like growth factor-I to influence gonadotrophin sensitivity of the non-human primate testis in-vivo. Eur. J. Endocrinol, 131: 405-412, 1994.
    • (1994) Eur. J. Endocrinol , vol.131 , pp. 405-412
    • Crawford, B.A.1    Handelsman, D.J.2
  • 14
    • 0027769745 scopus 로고
    • Comparison of four basic models of indirect pharmacodynamic responses
    • DAYNEKA, N. L., GARG, V. AND JUSKO, W. J.: Comparison of four basic models of indirect pharmacodynamic responses. J. Pharmacokinet. Biopharm. 21: 457-478, 1993.
    • (1993) J. Pharmacokinet. Biopharm. , vol.21 , pp. 457-478
    • Dayneka, N.L.1    Garg, V.2    Jusko, W.J.3
  • 19
    • 0342943149 scopus 로고
    • Androgens
    • ed. by F. Fuchs and A. Klopper, Harper & Row, Hagerstown, MD
    • GANDY, H. M.: Androgens. In Endocrinology of Pregnancy, ed. by F. Fuchs and A. Klopper, pp. 123-156, Harper & Row, Hagerstown, MD, 1977.
    • (1977) Endocrinology of Pregnancy , pp. 123-156
    • Gandy, H.M.1
  • 20
    • 0028316607 scopus 로고
    • Pharmacokinetics of once-a-month injectable contraceptives
    • GAHZA-FLORES, J.: Pharmacokinetics of once-a-month injectable contraceptives, Contraception 49: 347-359, 1994.
    • (1994) Contraception , vol.49 , pp. 347-359
    • Gahza-Flores, J.1
  • 23
    • 0002227995 scopus 로고
    • Testosterone and other androgens: Physiology, pharmacology and therapeutic use
    • ed. by L. J. DeGroot, W. B. Saunders, Philadelphia
    • HANDELSMAN, D. J.: Testosterone and other androgens: Physiology, pharmacology and therapeutic use. In Endocrinology, ed. by L. J. DeGroot, pp. 2351- 2361, W. B. Saunders, Philadelphia. 1994.
    • (1994) Endocrinology , pp. 2351-2361
    • Handelsman, D.J.1
  • 24
    • 0028851197 scopus 로고
    • Factors in the nonuniform induction of azoospermia by testosterone enanthate in normal men
    • HANDELSMAN, D. J., PARLEY, T. M. M., PEREGOUDOV, A., WAITES, G. M. H. AND WORLD HEALTH ORGANIZATION TASK FORCE ON METHODS FOR THE REGULATION OF MALE FERTILITY: Factors in the nonuniform induction of azoospermia by testosterone enanthate in normal men. Fertil. Steril. 63: 125-133, 1995.
    • (1995) Fertil. Steril. , vol.63 , pp. 125-133
    • Handelsman, D.J.1    Parley, T.M.M.2    Peregoudov, A.3    Waites, G.M.H.4
  • 25
    • 0025153432 scopus 로고
    • Highly vectorial secretion of inhibin by primate Sertoli cells in vitro
    • HANDELSMAN, D. J., SPALIVIERO, J. A. AND PHIHPARD, A. F.: Highly vectorial secretion of inhibin by primate Sertoli cells in vitro. J. Clin. Endocrinol. Metab. 71: 1235-1238, 1990.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , pp. 1235-1238
    • Handelsman, D.J.1    Spaliviero, J.A.2    Phihpard, A.F.3
  • 26
    • 0011458298 scopus 로고
    • Long-acting steroids in reproduction
    • JUNKMAN, K.: Long-acting steroids in reproduction. Recent Prog. Horm. Res. 13: 380-419, 1957.
    • (1957) Recent Prog. Horm. Res. , vol.13 , pp. 380-419
    • Junkman, K.1
  • 27
    • 0027943266 scopus 로고
    • Physiologic indirect response models characterise diverse types of pharmacodynamic effects
    • JUSKO, W. J. AND Ko, H. C.: Physiologic indirect response models characterise diverse types of pharmacodynamic effects. Clin. Pharmacol, Ther. 56: 406-419, 1994.
    • (1994) Clin. Pharmacol, Ther. , vol.56 , pp. 406-419
    • Jusko, W.J.1    Ko, H.C.2
  • 28
    • 0027049043 scopus 로고
    • Building population pharma- Cokinetic-pharmacodynamic models. I. Models for covariate effects
    • MANDEMA, J. W., VEROTTA, D. AND SHEINER, L. B.: Building population pharma- cokinetic-pharmacodynamic models. I. Models for covariate effects. J. Pharmacokinet. Biopharm. 20: 511-528, 1992.
    • (1992) J. Pharmacokinet. Biopharm. , vol.20 , pp. 511-528
    • Mandema, J.W.1    Verotta, D.2    Sheiner, L.B.3
  • 29
    • 0025266671 scopus 로고
    • Serum inhibin concentrations before and during gonadotropin treatment in men with hypogonadotropic hypogonadism: Physiological and clinical implications
    • McLACHLAN, R. I., FINKEL, D. M., BREMNER, W. J. AND SNYDER, P. J.: Serum inhibin concentrations before and during gonadotropin treatment in men with hypogonadotropic hypogonadism: Physiological and clinical implications. J. Clin. Endocrinol. Motab. 70: 1414-1419, 1990.
    • (1990) J. Clin. Endocrinol. Motab. , vol.70 , pp. 1414-1419
    • McLachlan, R.I.1    Finkel, D.M.2    Bremner, W.J.3    Snyder, P.J.4
  • 31
    • 0002427270 scopus 로고
    • Pharmacology and clinical uses of testosterone
    • ed. by E. Nieachlag and H. M. Behre, Springer-Verlag, Berlin
    • NIEHCHLAG, E. AND BEHKE, H. M.: Pharmacology and clinical uses of testosterone. In Testosterone: Action Deficiency Substitution, ed. by E. Nieachlag and H. M. Behre, pp. 92-114, Springer-Verlag, Berlin, 1990.
    • (1990) Testosterone: Action Deficiency Substitution , pp. 92-114
    • Niehchlag, E.1    Behke, H.M.2
  • 32
    • 0017096216 scopus 로고
    • Bioavailability and LH suppressing effect of different testosterone preparations in normal and hypogonadal men
    • NIESCHLAC, E., CUPPER, H. J., WIEGELMAN, W. AND WICKINGS, E. J.: Bioavailability and LH suppressing effect of different testosterone preparations in normal and hypogonadal men. Horm. Res. 7: 138-145, 1976.
    • (1976) Horm. Res. , vol.7 , pp. 138-145
    • Nieschlac, E.1    Cupper, H.J.2    Wiegelman, W.3    Wickings, E.J.4
  • 33
    • 0018843749 scopus 로고
    • Comparison of testosterone, dihydrotestosterone, luteinizing hormone, and follicle-stimulating hormone in serum after injection of testosterone enanthate or testosterone cypionate
    • SCHULTE-BEERBUHL, M. AND NIESCHLAG, E.: Comparison of testosterone, dihydrotestosterone, luteinizing hormone, and follicle-stimulating hormone in serum after injection of testosterone enanthate or testosterone cypionate, Fertil. Steril. 33: 201-203, 1980.
    • (1980) Fertil. Steril. , vol.33 , pp. 201-203
    • Schulte-Beerbuhl, M.1    Nieschlag, E.2
  • 34
    • 0021246217 scopus 로고
    • Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecarboxylate as assessed by serum and salivary testosterone levels
    • SCHURMEYER, T. AND NIESCHLAG, E.: Comparative pharmacokinetics of testosterone enanthate and testosterone cyclohexanecarboxylate as assessed by serum and salivary testosterone levels. Int. J. Androl. 7: 181-187, 1984.
    • (1984) Int. J. Androl. , vol.7 , pp. 181-187
    • Schurmeyer, T.1    Nieschlag, E.2
  • 36
    • 78651181332 scopus 로고
    • On the mechanism of action of nandrolone phenylpropionate and nandrolone decanoate in rats
    • VAN DER VIES, J.: On the mechanism of action of nandrolone phenylpropionate and nandrolone decanoate in rats. Acta Endocrinol. 49: 271-282, 1965.
    • (1965) Acta Endocrinol. , vol.49 , pp. 271-282
    • Van Der Vies, J.1
  • 37
    • 0019219058 scopus 로고
    • Testosterone radioimmunoassay: Rapid extraction technique for steroids based on kieselguhr mini-columns
    • VINING, R. F.: Testosterone radioimmunoassay: Rapid extraction technique for steroids based on kieselguhr mini-columns. Steroids 36: 149-159, 1980.
    • (1980) Steroids , vol.36 , pp. 149-159
    • Vining, R.F.1
  • 38
    • 0027266003 scopus 로고
    • Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. I. Plasma luteinizing hormone, follicle stimulating hormone, testosterone, estradiol. and inhibin concentrations
    • WALLACE, E. M., Gow, S. M. AND WU, F. C. W.: Comparison between testosterone enanthate-induced azoospermia and oligozoospermia in a male contraceptive study. I. Plasma luteinizing hormone, follicle stimulating hormone, testosterone, estradiol. and inhibin concentrations, J. Clin. Endocrinol. Metab. 77: 290-293, 1993.
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , pp. 290-293
    • Wallace, E.M.1    Gow, S.M.2    Wu, F.C.W.3
  • 39
    • 0022203791 scopus 로고
    • Pharmacokinetic parameters of nandrolone (19-nortestosterone) after intramuscular administration of nandrolone decanoate (Deca-Durabolin) to healthy volunteers
    • WIJNAND, H. P., BOSCH, A. M. G. AND DONKER, C. M.: Pharmacokinetic parameters of nandrolone (19-nortestosterone) after intramuscular administration of nandrolone decanoate (Deca-Durabolin) to healthy volunteers. Acta Endocrinol. Suppl. 271: 19-30, 1985.
    • (1985) Acta Endocrinol. Suppl. , vol.271 , pp. 19-30
    • Wijnand, H.P.1    Bosch, A.M.G.2    Donker, C.M.3
  • 40
    • 0025066149 scopus 로고
    • Contraceptive efficacy of testosterone-induced azoospermia in normal men
    • WORLD HEALTH ORGANIZATION TASK FORCE ON METHODS FOR THE REGULATION OF MALE FERTILITY: Contraceptive efficacy of testosterone-induced azoospermia in normal men. Lancet 336: 955-959, 1990.
    • (1990) Lancet , vol.336 , pp. 955-959
  • 41
    • 0027369185 scopus 로고
    • Comparison of two androgens plus depot-medroxyprogesterone acetate for suppression to azoospermia in Indonesian men
    • WORLD HEALTH ORGANIZATION TASK FORCE ON METHODS FOR THE REGULATION OF MALE FERTILITY: Comparison of two androgens plus depot-medroxyprogesterone acetate for suppression to azoospermia in Indonesian men. Fertil Steril. 60: 1062-1068, 1993.
    • (1993) Fertil Steril. , vol.60 , pp. 1062-1068
  • 42
    • 0023804439 scopus 로고
    • Release and absorption rate aspects of intramuscularly injected pharmaceuticals
    • ZUIDEMA, J., PIETERS, F. A. J. M. AND DUCHATEAU, G. S. M. J. E.: Release and absorption rate aspects of intramuscularly injected pharmaceuticals. Int. J. Pharm. 47: 1-12, 1988.
    • (1988) Int. J. Pharm. , vol.47 , pp. 1-12
    • Zuidema, J.1    Pieters, F.A.J.M.2    Duchateau, G.S.M.J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.