Evidence for two modes of allelic loss: Multifocal analysis on both early and advanced gastric carcinomas

Virchows Archiv

Volumn 438, Issue 1, 2001, Pages 31-38

  Chung, Yeun Jun ^a   Choi, Jung Ran ^a   Park, Sang Won ^a   Kim, Kyoung Mee ^a   Rhyu, Mun Gan ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Gastric carcinoma; Heterogeneity; Loss of heterozygosity; Multifocal analysis

Indexed keywords

ADVANCED CANCER; ARTICLE; CHROMOSOME 13Q; CHROMOSOME 17P; CHROMOSOME 18Q; CHROMOSOME 5Q; CHROMOSOME 9P; CONTROLLED STUDY; EARLY CANCER; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; STOMACH CARCINOGENESIS; STOMACH CARCINOMA;

ALLELES; CHROMOSOMES, HUMAN, PAIR 13; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 18; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 9; HUMANS; LOSS OF HETEROZYGOSITY; LYMPHOCYTES; MICROSATELLITE REPEATS; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 0035144469     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280000328     Document Type: Article

References (27)

1. Loss of heterozygosity of multiple tumor suppressor genes in human gastric cancers by polymerase chain reaction
2. Fractional allelic loss in gastric carcinoma correlates with growth patterns
3. Evidence of genetic progression in human gastric carcinomas with microsatellite instability
4. Relationship between intratumor histological heterogeneity and genetic abnormalities in gastric carcinoma with microsatellite instability
5. Loss of heterozygosity and loss of expression of the DCC gene in gastric cancer
6. Studying clonal heterogeneity in human cancers
7. Biology of early gastric carcinoma
8. Allelotype analysis of adenocarcinoma of the gastric cardia
9. Tumor suppressor genes: Evolving definitions in the genomic age
10. Loss of heterozygosity on chromosome 18q in cohesive-type gastric cancer is associated with tumor progression and poor prognosis
11. The general rules for the gastric cancer study in surgery and pathology. Part I. Clinical classification
12. Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas
13. Hereditary cancer, oncogenes, and antioncogenes
14. The two histological main types of gastric carcinoma: Diffuse and so-called intestinal type carcinoma
15. Gastric carcinoma
16. Somatic mutations detected by mini- and microsatellite DNA markers reveal clonal intratumor heterogeneity in gastrointestinal cancers
17. Loss of heterozygosity during the development and progression of differentiated adenocarcinoma of the stomach
18. Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis
19. Loss of heterozygosity on the short arm of chromosome 9 without p16 gene mutation in gastric carcinomas
20. Allelic imbalance in gastric cancer: An affected site on chromosome arm 3p
21. Genetic alterations in human gastrointestinal cancers. The application to molecular diagnosis
22. Molecular pathogenesis of adenoma and differentiated adenocarcinoma of the stomach
23. Allelotype of adenoma and differentiated adenocarcinoma of the stomach
24. Frequent loss of heterozygosity at the DCC locus in gastric cancer
25. Allelotype of pediatric rhabdomyosarcoma
26. Genetic alterations in gastric cancer: Relation to histological subtypes, tumor stage, and Helicobacter pylori infection
27. Allelotype of gastric adenocarcinoma