Loss of heterozygosity of multiple tumor suppressor genes in human gastric cancers by polymerase chain reaction

Laboratory Investigation

Volumn 74, Issue 4, 1996, Pages 835-841

  Cho, Jeong Hee ^b   Noguchi, Masayuki ^a   Ochiai, Atsushi ^a   Hirohashi, Setsuo ^a,c  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b Dankook University College of Medicine   (South Korea)

^c NATIONAL CANCER CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; PROTEIN P53;

ALLELE; ARTICLE; CHROMOSOME; COLON CANCER; COLON POLYPOSIS; CONTROLLED STUDY; GENE ACTIVATION; HETEROZYGOSITY; HUMAN; HUMAN TISSUE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RETINOBLASTOMA; STOMACH CANCER; TUMOR SUPPRESSOR GENE;

BASE SEQUENCE; CHROMOSOME DELETION; GENES, APC; GENES, DCC; GENES, RETINOBLASTOMA; GENES, TUMOR SUPPRESSOR; HUMANS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; STOMACH NEOPLASMS;

EID: 0029986483     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Ashton-Richardt PG, Wyllie AH, Bired CC, Dunlop MG, Steel CM, Morris RG and Piris J (1991). MCC, a candidate familial polyposis gene in 5q 21, shows frequent allele loss in colorectal and lung cancer. Oncogene 6:1881-1886.
2. Boynton RF, Blount PL, Yin J, Brown VL, Huang Y, and Tong Y (1992). Loss of heterozygosity involving the APC and MCC genetic loci occurs the majority of human esophageal cancers. Proc Natl Acad Sci U S A 89:3385-3388.
3. Cho JH, Noguchi M, Ochiai A, Uchino S, and Hirohashi S (1994). Analysis of regional differences of p53 mutation in advanced gastric carcinoma: Relation to heterogeneous differentiation and invasiveness. Mod Pathol 7:205-211.
4. Fearon ER, Cho KR, Nigro JM, Kern SE, Simons JW, and Ruppert JM (1990). Identification of a chromosome 18q gene that is altered in colorectal cancers. Science 247:49-56.
5. Fong CT, Dracopoli MC, White PS, Merrill PT, Griffin RC, and Housman DE (1989). Loss of heterozygosity for the short arm of chromosome in human neuroblastomas: Correlation with N-myc amplification. Proc Natl Acad Sci USA 86:3753-3757.
6. Hirohashi S and Sugimura T (1991). Genetic alterations in human gastric cancer. Cancer Cells 3:49-52.
7. Horii A, Nakatsuru S, Miyoshi Y, Ichii S, Nagase H, and Kato Y (1992). The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 52:3231-3233.
8. Huang Y, Boynton RF, Blonunt PL, Silverstein RJ, Yin J, and Tong Y (1992). Loss of heterozygosity involves multiple tumor suppressor genes in human esophageal cancer. Cancer Res 52:6525-6530.
9. Japanese Research Society for Gastric Cancer (1993). The general rules for gastric study, ed 11. Tokyo: Japanese Research Society for Gastric Cancer.
10. Kim JH, Takahashi T, Chiba I, Park J-G, Birrer MJ, and Roh JK (1991). Occurence of p53 gene abnormalities in gastric carcinoma tumors and cell lines. J Natl Cancer Inst 83:938-943.
11. Kinzler KW, Nibert MC, Su L-K, Vogelstein B, Bryan TM, and Levy DB (1991). Identification of FAP locus genes from chromosome 5q 21. Science 353:661-665.
12. Lauren P (1965). The two histological main types of gastric carcinoma; diffuse and so-called intestinal-types carcinoma. An attempt at histochemical classification. Acta Pathol Microbiol Scand 64:31-49.
13. Matozaki T, Sakamoto C, and Matsuda K (1992). Missense mutations and a deletion of the p53 gene in human gastric cancer. Biochem Biophys Res Commun 189:215-223.
14. McGee TL, Cowley GS, Yandell DW, and Dryja TP (1990). Detection of the xba I RFLP within the retinoblastoma locus by PCR. Nucleic Acids Res 18:207.
15. McGee TL, Yandell DW, and Dryja TP (1989). Structure and partial genomic sequence of the human retinoblastoma susceptibility gene. Gene 80:119-128.
16. Meltzer SJ, Yin J, Huang Y, McDaniel TK, Newkirk C, and Iseri O (1991). Reduction to homozygosity involving p53 esophageal cancers demonstrated by the polymerase chain reaction. Proc Natl Acad Sci U S A 88:4976-4980.
17. Miyoshi Y, Ando H, Nishisho I, Horii A, Miki Y, and Mori T (1992a). Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients. Proc Natl Acad Sci U S A 89:4452-4456.
18. Miyoshi Y, Nagase H, Ando H, Horii A, Ichii S, and Nakatsuru S (1992b). Somatic mutations of the APC gene in colorectal tumors: Mutation cluster region in the APC gene. Hum Mol Genet 1:229-2335.
19. Nakatsuru S, Yanagisawa A, Ichii S, Tahara E, Kato Y, and Nakamura Y (1992). Somatic mutations of the APC gene in gastric cancer: Frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum Mol Genet 1:559-563.
20. Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, and Horii A (1991). Mutations of chromosome 5q 21 genes in FAP and colorectal cancer patients. Science 253:665-669.
21. Sano J, Tsujino T, Yoshida K, Nakayama H, Harumar K, and Ito H (1991). Frequent loss of heterozygosity on chromosomes 1q, 5q and 17q in human gastric carcinomas. Cancer Res 51:2926-2931.
22. Tahara E (1992). Development, proliferation, and progression of human gastric carcinoma. Trans Soc Pathol JPN 81(2):21-49.
23. Tahara E (1993). Molecular mechanism of stomach carcinogenesis. Cancer Res Clin Oncol 119:1-8.
24. Tamura G, Kihana T, Nomura K, Terada M, Sugimura T, and Hirohashi S (1991). Detection of frequent p53 mutation in primary gastric cancer by cell sorting and polymerase chain reaction-single strand conformation polymorphism analysis. Cancer Res 51:3056-3058.
25. Uchino S, Noguchi M, Hirota T, Itabashi M, Saito T, Kobayashi M, and Hirohashi S (1992a). High incidence of nuclear accumulation of p53 protein in gastric cancer. Jpn J Clin Oncol 22:225-231.
26. Uchino S, Noguchi M, Ochiai A, Saito T, Kobayashi M, and Hirohashi S (1993). p53 mutation in gastric cancer: A genetic model for carcinogenesis is common to gastric and colorectal cancer. Int J Cancer 54:759-764.
27. Uchino S, Tsuda H, Yokota J, Terada M, and Saito T (1992b). Frequent loss of heterozygosity at the DCC locus in gastric cancer. Cancer Res 52:3099-3102.
28. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Perisinger AC, and Leppert M (1988). Genetic alterations during colorectal-tumor development. N Engl J Med 319:525-532.
29. Wagata T, Ishizak K, Imamura M, Shimada Y, Ikenaga M, and Tobe T (1991). Deletion of 17p and amplification of the int-2 gene in esophageal carcinomas. Cancer Res 51:2113-2117.
30. Hirohashi S (1991). p53 gene mutations in gastric cancer metastases and in gastric cancer cell lines derived from metastases. Cancer Res 52:5800-5805.
31. Yandell DW and Dryja TP (1989). Detection of DNA sequence polymorphisms by enzymatic amplification and direct genomic sequencing. Am J Hum Genet 45:547-555.