Terbinafine-associated inhibition of dextromethorphan metabolism in Chinese projects

British Journal of Clinical Pharmacology

Volumn 51, Issue 1, 2001, Pages 107-108

  Cai, W M ^a,b,c   Chen, B ^a,b   Ling, S S ^a,b   Zhang, Y D ^a,b  

^a JINLING HOSPITAL   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 2D6; DEXTROMETHORPHAN; TERBINAFINE;

ADULT; ANTIFUNGAL ACTIVITY; CHINA; CLINICAL ARTICLE; DRUG CROSS REACTIVITY; DRUG METABOLISM; ENZYME INHIBITOR INTERACTION; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; MALE; PHENOTYPE; PRIORITY JOURNAL;

ADULT; ANTIFUNGAL AGENTS; ANTITUSSIVE AGENTS; CHINA; CYTOCHROME P-450 CYP2D6; DEXTROMETHORPHAN; FEMALE; GENOTYPE; HUMANS; MALE; NAPHTHALENES; PHENOTYPE;

EID: 0035142319     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.2001.01322.x     Document Type: Letter

References (10)

1. Potent inhibition of cytochrome P-4502D6-mediated dextromethorphan O-demethylation by terbinafine
2. Investigation of terbinafine as a CYP2D6 inhibitor in vivo
3. Nortriptyline intoxication induced by terbinafine
4. Dextromethorphan metabolic phenotyping in a Chinese population
5. Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylation of debrisoquine and S-mephenytoin
6. Relationship between genetic polymorphism of cytochrome P450 and dextromethorphan oxidative metabolism
7. High performance liquid chromatographic determination of dextromethorphan and its metabolite in human urine
8. Polymorphic dextromethorphan metabolism: Co-segregation of oxidative O-demethylation with debrisoquin hydroxylation
9. Pharmacogenetic phenotyping and genotyping-present status and future petential
10. Cytochrome P4502D6 gene polymorphism in Chinese population