High performance liquid chromatographic determination of dextromethorphan and its metabolite in human urine

Yaoxue Xuebao

Volumn 32, Issue 11, 1997, Pages 861-864

  Cai, W M ^a   Chen, B ^a   Chu, X ^a  

^a NANJING GENERAL HOSPITAL OF NANJING MILITARY COMMAND   (China)

Author keywords

Dextromethorphan; Dextrophan; High performance liquid chromatography

Indexed keywords

DEXTROMETHORPHAN; DEXTRORPHAN;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; METHODOLOGY; URINE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEXTROMETHORPHAN; DEXTRORPHAN; HUMANS;

EID: 0031261047     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

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3. Kupfer A, Schmidt B, Preisig R, et al. Dextromethorphan as a safe probe for debrisoquin hydroxylation polymorphism. Lancet, 1984,2:517
4. Schimid B, Bircher J, Preisig R, et al. Polymorphic dextromethorphan metabolism: cosegregation of O-demethylation with debrisoquin hydroxylation. Clin Pharmacol Ther, 1985,38:618
5. Guttendorf RJ, Wedlund PJ, Blake J, et al. Simplified phenotyping with dextromethorphan by thin-layer chromatography: application to clinical laboratory screening for deficiencies in oxidative drug metabolism. Ther Drug Monit, 1988,10:490
6. Park YH, Kullberg MP, Hinsvark ON. Quantitative determination of dextromethorphan and three metabolites in urine by reverse-phase high-performance liquid chromatography. J Pharm Sci, 1984,73:24