Characterization of nuclear factors binding to AT-rich element in the rat p53 promoter

Journal of Cellular Biochemistry

Volumn 80, Issue 4, 2001, Pages 580-588

  Lee, Minhyung ^a,b   Yu, Sunhee ^a   Lee, Young Sam ^a   Park, Jong Sang ^a  

^a Seoul National University   (South Korea)

^b UNIVERSITY OF UTAH   (United States)

Author keywords

AT rich element; Cis regulatory element; P53 tumor suppressor; Promoter; Transcription regulation

Indexed keywords

DEOXYRIBONUCLEASE; NUCLEAR FACTOR; OLIGONUCLEOTIDE; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA FOOTPRINTING; FEMALE; IONIC STRENGTH; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN STABILITY; RAT; SOUTHERN BLOTTING; TRANSCRIPTION REGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CELL NUCLEUS; CHELATING AGENTS; DEOXYRIBONUCLEASE I; DNA; DNA FOOTPRINTING; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASE K; ENDOPEPTIDASES; FEMALE; GENES, P53; MICE; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; RATS; RATS, WISTAR; SODIUM CHLORIDE; TEMPERATURE; TRYPSIN; UREA;

MURINAE;

EID: 0035142313     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-4644(20010315)80:4<580::AID-JCB1012>3.0.CO;2-C     Document Type: Article

References (29)

1. The 5' region of the p53 gene: Evolutionary conservation and evidence for a negative regulatory element
2. Chromosome translocation activates heterogeneously initiated, bipolar transcription of a mouse c-myc gene
3. In vivo evidence for binding of p53 to consensus binding sites in the p21 and GADD45 genes in response to ionizing radiation
4. Characterization of two distinct families of transcription factors that bind to the CCAAT box region of the human COL1A2 gene
5. A p53-dependent mouse spindle checkpoint
6. WAF1, a potential mediator p53 tumor suppression
7. YY1 and NFl both activate the human p53 promoter by alternatively binding to a composite element, and YY1 and E1A cooperate to amplify p53 promoter activity
8. Protein binding elements in the promoter region of the mouse p53 gene
9. Identification of an upstream region of the mouse p53 promoter critical for transcriptional expression
10. p53 mutations in human cancers
11. Properties of a CCAAT box-binding protein
12. Characterization and sequence of the promoter region of the human epidermal growth factor receptor gene
13. Expression of human p53 requires synergistic activation of transcription from the p53 promoter by AP1-, NF-kappaB and Myc/Max
14. p53: Puzzle and paradigm
15. Characterization of the human p53 gene
16. Transcription of the rat p53 gene is mediated by factor binding to two recognition motifs of NFl-like protein
17. A 40-kDa NF1like protein, not YY1, binds to the rat p53 promoter for transactivation in various rat organs
18. Biochemical characterization of a nuclear factor that binds to NFl-like elements in the rat p53 promoter
19. The 1993 Walter Hubert lecture: The role of the p53 tumor suppressor gene in tumorigenesis
20. p53, the cellular gatekeeper for growth and division
21. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
22. Methionyl-tRNA synthetase of Escherichia coli. a zinc metalloprotein
23. c-Myc transactivates the promoter of the p53 tumor suppressor through an essential downstream CACGTG motif
24. The helix-loop-helix containing transcription factor USF binds to and transactivates the promoter of the p53 tumor suppressor gene
25. HMG CoA reductase: A negatively regulated gene with unusual promoter and 5' untranslated regions
26. Transactivation of the human p53 tumor suppressor gene by c-Myc/Max contributes to elevated mutant p53 expression in some tumors
27. Positive and negative regulatory elements in the murine p53 promoter
28. Characterization of the human p53 gene promoter
29. NF-κB activation of p53