Mice lacking interleukin-2 (IL-2)/IL-15 receptor β chain are susceptible to infection with avirulent Salmonella enterica subsp. enterica serovar Choleraesuis but mice lacking IL-2 are resistant

Infection and Immunity

Volumn 69, Issue 2, 2001, Pages 1226-1229

  Nishimura, H ^a   Tagaya, M ^a   Tsunobuchi, H ^a   Suzuki, H ^a   Nakashima, I ^a   Yoshikai, Y ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA CHAIN; CONTROLLED STUDY; IMMUNE RESPONSE; IMMUNITY; INFECTION RESISTANCE; INFECTION SENSITIVITY; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; SALMONELLA CHOLERAESUIS; SALMONELLA ENTERICA; SALMONELLOSIS; SIGNAL TRANSDUCTION;

ANIMALS; DISEASE SUSCEPTIBILITY; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-2; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; RECEPTORS, INTERLEUKIN-15; RECEPTORS, INTERLEUKIN-2; SALMONELLA ENTERICA; SALMONELLA INFECTIONS, ANIMAL; TH1 CELLS;

EID: 0035142107     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.69.2.1226-1229.2001     Document Type: Article

References (11)

1. Induction of γ/δ T cells in murine salmonellosis by an avirulent but not by a virulent strain of Salmonella choleraesuis
2. Endogenous IL-15 might be responsible for early protection by natural killer cells against infection with an avirulent strain of Salmonella choleraesuis in mice
3. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
4. Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivo
5. IL-15 is a novel growth factor for murine γδ T cells induced by Salmonella infection
6. Development and function of T cells in mice rendered interleukin-2 deficient by gene targeting
7. Regulation of the IL-12/IL-12R axis: A critical step in T-helper cell differentiation and effector function
8. Deregulated T cell activation and autoimmunity in mice lacking interleukin-2 receptor β
9. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain
10. Regulation of the interleukin (IL)-12Rβ2 subunit expression in developing T helper (Th1) and Th2 cells
11. Potent and selective stimulation of memory-phenotype CD8+T cells in vivo by IL-15