Reversible down-regulation of connexin43 expression in acute cardiac allograft rejection

Journal of Heart and Lung Transplantation

Volumn 20, Issue 1, 2001, Pages 93-97

  Lerner, Deborah L ^a   Chapman, Qiauna ^a   Green, Karen G ^a   Saffitz, Jeffrey E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNEXIN 43; GAP JUNCTION PROTEIN;

CONFERENCE PAPER; CONTROLLED STUDY; GAP JUNCTION; GRAFT REJECTION; HEART MUSCLE BIOPSY; HEART TRANSPLANTATION; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ACUTE DISEASE; ADULT; BIOLOGICAL MARKERS; CONNEXIN 43; DOWN-REGULATION; ENDOCARDIUM; GRAFT REJECTION; HEART TRANSPLANTATION; HUMANS; MICROSCOPY, FLUORESCENCE; MYOCARDIUM; SEVERITY OF ILLNESS INDEX;

EID: 0035141037     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1053-2498(00)00169-8     Document Type: Conference Paper

References (18)

1. Changes in left ventricular systolic function that accompany rejection of the transplanted heart; a serial radionuclide assessment of fifty-three consecutive cases
2. Disturbed connexin43 gap junction distribution correlates with the location of reentrant circuits in the epicardial border zone of healing canine infarcts that cause ventricular tachycardia
3. Mechanisms of remodeling of gap junction distributions and the development of anatomic substrates of arrhythmias
4. Downregulation of immunodetectable connexin43 and decreased gap junction size in the pathogenesis of chronic hibernation in the human left ventricle
5. A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection; heart rejection study group
6. Differential expression of gap junction proteins in the canine sinus node
7. Expression of multiple gap junction proteins in human fetal and infant hearts
8. Effects of diminished expression of connexin43 on gap junction number and size in ventricular myocardium
9. Molecular mechanism of contractile dysfunction in cardiac allograft rejection
10. Endogenous nitric oxide in cardiovascular disease and transplantation
11. Tumour necrosis factor alpha and the cardiovascular system; its role in cardiac allograft rejection and heart disease
12. Heterotypic heart transplantation; electrophysiologic changes during acute rejection
13. Arrhythmias after orthotopic cardiac transplantation; prevalence and determinants during initial hospitalization and late follow-up
14. Sudden cardiac death in cardiac transplant recipients
15. Severe and early alteration of action potential during acute cardiac rejection in rats
16. Disparate effects of deficient expression of connexin43 on atrial and ventricular conduction; evidence for chamber-specific molecular determinants of conduction
17. Conduction disturbances and increased atrial vulnerability in connexin40-deficient mice analyzed by transesophageal stimulation