Role of granuloma in the immunopathogenesis of Crohn's disease

Digestion

Volumn 63, Issue SUPPL. 1, 2001, Pages 43-47

  Matsumoto, T ^a   Nakamura, S ^a   Jin no, Y ^a   Sawa, Y ^a   Hara, J I ^a   Oshitani, N ^a   Arakawa, T ^a   Otani, H ^a   Nagura, H ^a  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Crohn's disease; Granuloma; Macrophage; T cell stimulation; Ulcerative colitis

Indexed keywords

B7 ANTIGEN; CD86 ANTIGEN; MESSENGER RNA;

CONFERENCE PAPER; CROHN DISEASE; GRANULOMA; HELPER CELL; HISTOPATHOLOGY; HUMAN; IMMUNOPATHOGENESIS; LYMPHOCYTE PROLIFERATION; MEMORY CELL; PRIORITY JOURNAL;

EID: 0035137347     PISSN: 00122823     EISSN: None     Source Type: Journal    
DOI: 10.1159/000051910     Document Type: Conference Paper

References (25)

1. Mapping of susceptibility locus foe Crohn's disease on chromosome 16
2. Genetics of inflammatory bowel disease
3. Characteristics of unclassified Mycobacterium species isolated from patients with Crohn's disease
4. Specific detection of Mycobacterium paratuberculosis DNA associated with granulomatous tissue in Crohn's disease
5. Mycobacterium paratuberculosis DNA in Crohn's disease
6. Immunohistochemical examination for mycobacteria in intestinal tissues from patients with Crohn's disease
7. Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum
8. Postoperative recurrence of Crohn's disease: The enemy is within the fecal stream
9. Evidence of persistent measles virus infection in Crohn's disease
10. Granulomatous vasculitis in Crohn's disease
11. Perinatal measles infection and subsequent Crohn's disease
12. Measles vaccination as a risk factor for inflammatory bowel disease
13. In situ expression of the cell adhesion molecules in inflammatory bowel disease; Evidence of immunologic activation of vascular endothelial cells
14. Possible role of vascular endothelial cells in immune responses I colonic mucosa examined immunocytochemically in subjects with and without ulcerative colitis
15. Expression of costimulatory molecules B7-1 and B7-2 in macrophages and granulomas of Crohn's disease: Demonstration of cell-to-cell contact with T lymphocytes
16. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
17. Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)
18. Increased concentration of interleukin-1 beta, interleukin-2, and soluble interleukin-2 receptor in endoscopical mucosal biopsy specimens with active inflammatory bowel disease
19. Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn's disease but not ulcerative colitis
20. Loss of interleukin-2-producing intestinal CD4+ T cells in inflammatory bowel disease
21. Type 1 T-helper cell predominance in granulomas of Crohn's disease
22. Characterization of T cell repertoire changes in acute Kawasaki disease
23. Analysis of function, specificity and T cell receptor expression of cloned mucosal T cell lines in Crohn's disease
24. Selective expansion of specific T cell receptors in the inflamed colon of Crohn's disease
25. CD4+ cell oligoclonality in Crohn's disease: Evidence for an antigen-specific response