Effects of zinc acetate on splenocytes of endotoxemic mice: Enhanced immune response, reduced apoptosis, and increased expression of heat shock protein 70

Journal of Laboratory and Clinical Medicine

Volumn 137, Issue 1, 2001, Pages 28-37

  Unoshima, Masako ^a   Nishizono, Akira ^a   Takita Sonoda, Yoshiko ^a   Iwasaka, Hideo ^a   Noguchi, Takayuki ^a  

^a OITA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035136675     PISSN: 00222143     EISSN: None     Source Type: Journal    
DOI: 10.1067/mlc.2001.111514     Document Type: Article

References (39)

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3. Pathogenetic mechanisms of septic shock
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6. Study of immune function of cancer patients influenced by supplemental zinc or selenium-zinc combination
7. The dynamic link between the integrity of the immune system and zinc status
8. Zinc regulates cytokine induction by superantigens and lipopolysaccharide
9. Induction of cytokines by zinc ions in human peripheral blood mononuclear cells and separated monocytes
10. Induction of interferon-γ in human leukocyte cultures stimulated by Zn2+
11. Zinc-altered immune function and cytokine production
12. Zinc deficiency and immune function
13. Physiological and pharmacological effects of zinc on immune response
14. Effect of zinc on immune functions and host resistance against infection and tumor challenge
15. The cytotoxic effect of endotoxin on bone marrow cells in zinc deficient rats
16. Inhibition of lethality in endotoxin-challenged mice treated with zinc chloride
17. Zn2+ inhibits nitric oxide formation in response to lipopolysaccharides: Implication in its anti-inflammatory activity
18. Role of zinc in the abatement of hepatocellular damage and mortality incidence in endotoxemic rats
19. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
20. Monocyte response to bacterial toxins, expression of cell surface receptors, and release of anti-inflammatory cytokines during sepsis
21. Zinc modulates the mitogenic activation of human peripheral blood lymphocytes
22. Metal cation requirements for phytohemagglutinin-induced transformation of human peripheral blood lymphocytes
23. Zinc inhibits UV radiation-induced apoptosis but fails to prevent subsequent cell death
24. The influence of heat shock protein 70 induction on hemodynamic variables in a porcine model of recurrent endotoxemia
25. Influence of heat shock protein 70 and metallothionein induction by zinc-bis-(DL-hydrogenaspartate) on the release of inflammatory mediators in a porcine model of recurrent endotoxemia
26. Induction of heat shock protein 70 by zinc-bis-(DL-hydrogenaspartate) reduces cytokine liberation, apoptosis, and mortality rate in a rat model of LD 100 endotoxemia
27. Heat shock proteins increase resistance to apoptosis
28. Role of the human heat shock protein hsp70 in protection against stress-induced apoptosis
29. Zinc suppresses apoptosis of U937 cells induced by hydrogen peroxide through an increase of the Bcl-2/Bax ratio
30. Heat stress increases survival rates in lipopolysaccharide-stimulated rats
31. Induction of the heat shock response reduces mortality rate and organ damage in a sepsis-induced acute lung injury model
32. Sodium arsenite induces heat shock protein-72 kilodalton expression in the lungs and protects rat against sepsis
33. Significant contribution of spleen cells in mediating the lethal effects of endotoxin in vivo
34. Mechanisms involved in the pathogenesis of sepsis are not necessarily reflected by in vitro cell activation studies
35. Interaction of NK lysin, a peptide produced by cytolytic lymphocytes, with endotoxin
36. Essential role of gamma interferon in survival of colon ascendens stent peritonitis, a novel murine model of abdominal sepsis
37. Lymphocyte-derived cytokines augment macrophage tumor necrosis factor-α and interleukin-6 secretion during experimental gram-negative bacterial sepsis
38. Korrelation von immunfunktion mit überleben