Efficient lentiviral transduction of primary human acute myelogenous and lymphoblastic leukemia cells

Haematologica

Volumn 86, Issue 1, 2001, Pages 13-16

  Biagi, E ^a   Bambacioni, F ^a   Gaipa, G ^a   Casati, C ^a   Golay, J ^a   Biondi, A ^a   Introna, M ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Cancer vaccines; Gene therapy; Human leukemia; Retroviruses

Indexed keywords

CANCER VACCINE; FLT3 LIGAND; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 3; STEM CELL FACTOR; VIRUS VECTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; B LYMPHOBLAST; CELL PROLIFERATION; CELL VIABILITY; CLINICAL ARTICLE; CYTOKINE RELEASE; GENE THERAPY; GENETIC MANIPULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNOGENICITY; LENTIVIRINAE;

BONE MARROW CELLS; CELL CYCLE; CELL DIVISION; GENES, REPORTER; GLYCEROL KINASE; GREEN FLUORESCENT PROTEINS; HIV-1; HUMANS; LEUKEMIA, LYMPHOCYTIC, ACUTE; LEUKEMIA, MYELOCYTIC, ACUTE; LUMINESCENT PROTEINS; PROMOTER REGIONS (GENETICS); TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0035135880     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Enhanced immune costimulatory activity of primary acute myeloid leukaemia blasts after retrovirus-mediated gene transfer of B7.1
2. Gene immunotherapy in murine acute myeloid leukemia: Granulocyte-macrophage colony-stimulating factor tumor cell vaccines elicit more potent antitumor immunity compared with B7 family and other cytokine vaccines
3. Vaccines with interleukin-12-transduced acute myeloid leukemia cells elicit very potent and long-lasting protective immunity
4. Gene delivery to human B-precursor acute lymphoblastic leukemia cells
5. Lentiviral vectors for efficient delivery of CD-80 and granulocyte-macrophage-colony-stimulating factor in human acute lymphoblastic leukemia and acute myeloid leukemia cells to induce antileukemic immune responses
6. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector
7. Stable transduction of quiescent CD34+CD38- human hematopoietic cells by HIV-1-based lentiviral vectors
8. Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo
9. Rapid retroviral infection of human haemopoietic cells of different lineages: Efficient transfer in fresh T cells
10. Genetic modification of human T cells with CD20: A strategy to purify and lyse transduced cells with anti-CD20 antibodies
11. Effects of FLT3 ligand on myeloid leukemia cell growth: Heterogeneity in response and synergy with other hematopoietic growth factors
12. Analysis of PCP: Data to determine the fraction of cells in the various phases of the cell cycle
13. Comparative studies of different stromal cell microenvironments in support of human B-cell development
14. Cytokine signals are sufficient for HIV-1 infection of resting human T lymphocytes
15. Learning from lentivirus
16. Commentary: Development of optimized vectors for gene therapy