Interleukin-11 receptor expression in primary ovarian carcinomas

Gynecologic Oncology

Volumn 80, Issue 2, 2001, Pages 121-127

  Campbell, Cara L ^a   Guardiani, Rachel ^a   Ollari, Christopher ^b   Nelson, Beth E ^b   Quesenberry, Peter J ^a   Savarese, Todd M ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b University of Massachusetts   (United States)

Author keywords

Gp130; Interleukin 11; Interleukin 11 receptor; Ovarian

Indexed keywords

DNA FRAGMENT; FAS ANTIBODY; GLYCOPROTEIN GP 130; INTERLEUKIN 11; INTERLEUKIN 11 RECEPTOR; MESSENGER RNA; PACLITAXEL; RECEPTOR SUBUNIT; RECOMBINANT INTERLEUKIN 11; THYMIDINE;

APOPTOSIS; ARTICLE; BENIGN TUMOR; CONTROLLED STUDY; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALIGNANT NEOPLASTIC DISEASE; OVARY CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STROMA;

EID: 0035134951     PISSN: 00908258     EISSN: None     Source Type: Journal    
DOI: 10.1006/gyno.2000.6064     Document Type: Article

References (38)

1. Cancer statistics, 1999
2. Incessant ovulation and ovarian cancer
3. Epithelial ovarian cancer: A cytokine propelled disease?
4. Expression of cytokines and their receptors in human primary ovarian tumors
5. Involvement of gp130/interleukin-6 receptor transducing component in interleukin-11 receptor
6. The human IL-11 receptor requires gp130 for signalling: Demonstration by molecular cloning of the receptor
7. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine
8. Genomic sequence and chromosomal location of human interleukin (IL)-11 gene
9. Structure-function relationships in human interleukin-11
10. Interleukin-11: Review of molecular, cell biology and clinical use
11. Thrombopoietic activity of recombinant human interleukin-11 in cancer patients receiving chemotherapy
12. Interleukin-11 inhibits adipogenesis and stimulates myelopoiesis in human long-term marrow cultures
13. Interleukin-11: A new cytokine critical for osteoblast development
14. IL-11, a pleotrophic cytokine: Exciting new effects of IL-11 on gastrointestinal mucosal biology
15. Interleukin-11 protects the clonogenic stem cells in murine small intestinal crypts from impairment of their reproductive capacity by radiation
16. Interleukin-11 prevents apoptosis and acclerates recovery of small intestinal mucosa in mice treated with combined chemotherapy and radiation
17. Protective effects of interleukin-11 in a murine model of ischemic bowel necrosis
18. IL-11 enhances survival and decreases TNF production after radiation-induced thoracic injury
19. Interleukin-6 family of cytokines and gp130
20. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
21. Tyrosine phosphorylation of JAK-TYK kinases in malignant plasma cell lines growth-stimulated by interleukins 6 and 11
22. Identification of a 130 kilodalton tyrosine-phosphorylated protein induced by interleukin-11 as JAK2 tyrosine kinase, which associates with gp130 signal transducer
23. Activation of the signal transducer gp130 by interleukin-11 and interleukin-6 is mediated by similar molecular interactions
24. Involvement of MAP kinase and pp90rsk activation in signaling pathways shared by interleukin-11, interleukin-6, leukemia inhibitory factor and oncostatin M in mouse 3T3-L 1 cells
25. Activation of src-family protein tyrosine kinases and phosphatidylinositol-3 kinase in 3T3-L1 mouse preadipocytes by interleukin-11
26. Complex formation of JAK2 with PP2A, PI3K, and yes in response to the hematopoietic cytokine interleukin-11
27. Interleukin (IL)-11-mediated signal transduction
28. Activation of Fas ligand/receptor system kills ovarian cancer cell lines by an apoptotic mechanism
29. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
30. Coexpression of IL-11 and IL-11 receptor in primary neoplasms (ovarian) and cultured cell lines
31. Expression of macrophage colony stimulating factor (M-CSF), interleukin-6 (IL-6), interleukin-1 beta (IL-1 beta), interleukin-11 (IL-11) and tumour necrosis factor (TNF-alpha) in p53-characterized human ovarian carcinomas
32. Detection of immunoreactive interleukin-11 in human follicular fluid: Correlations with ovarian steroid, insulin-like growth factor I levels and follicular maturity
33. Infertility in femal mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation
34. Expression and function of members of the cytokine receptor superfamily on breast cancer cells
35. Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells
36. Production and regulation of interleukin-11 by breast cancer cells
37. Interleukin-11 induces intestinal epithelial cell growth arrest through effects on retinoblastoma protein phosphorylation
38. Increased expression of the interleukin-11 receptor and evidence of STAT-3 activation in primary prostate carcinoma