Cellular splicing factor RAF-2p48/NPI-5/BAT1/UAP56 interacts with the influenza virus nucleoprotein and enhances viral RNA synthesis

Journal of Virology

Volumn 75, Issue 4, 2001, Pages 1899-1908

  Momose, F ^a   Basler, C F ^a   O'Neill, R E ^a   Iwamatsu, A ^a   Palese, P ^a   Nagata, K ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; RAF 2P48 PROTEIN; RNA POLYMERASE; SPLICED LEADER RNA; UNCLASSIFIED DRUG; VIRUS NUCLEOPROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ARTICLE; DNA LIBRARY; HELA CELL; HUMAN; HUMAN CELL; INFLUENZA VIRUS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RNA SYNTHESIS; SPLICEOSOME; VIRUS REPLICATION;

ADENOSINE TRIPHOSPHATASES; GENE EXPRESSION REGULATION, VIRAL; HELA CELLS; HUMANS; INFLUENZA A VIRUS; NUCLEAR PROTEINS; NUCLEOPROTEINS; RNA HELICASES; RNA SPLICING; RNA, VIRAL; SPLICEOSOMES; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 0035133124     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.75.4.1899-1908.2001     Document Type: Article

References (56)

1. Identification of an RNA binding region within the N-terminal third of the influenza A virus nucleoprotein
2. Synthesis of the templates for influenza virion RNA replication in vitro
3. Molecular model of a eucaryotic transcription complex: Functions and movements of influenza P proteins during capped RNA-primed transcription
4. Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3′-end processing machinery
5. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
6. Structure of the ribonucleoprotein of influenza virus
7. Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families
8. In vitro synthesis of full-length influenza virus complementary RNA
9. The 3′ and 5′-terminal sequences of influenza A, B and C virus RNA segments are highly conserved and show partial inverted complementarity
10. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
11. Identification of amino acid residues of influenza virus nucleoprotein essential for RNA binding
12. Sequence of the lacI gene
13. 65 recruits a novel human DEAD box protein required for the U2 snRNP-branchpoint interaction
14. Interaction of influenza virus polymerase with viral RNA in the 'corkscrew' conformation
15. Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus
16. Influenza virus NS1 protein alters the subnuclear localization of cellular splicing components
17. Influenza A virus RNA-dependent RNA polymerase: Analysis of RNA synthesis in vitro
18. How does influenza virus regulate gene expression at the level of mRNA translation? Let us count the ways
19. Elution of proteins from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: Results with sigma subunit of Escherichia coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes
20. The molecular anatomy of influenza virus RNA polymerase
21. RNA polymerase of influenza virus: Role of NP in RNA chain elongation
22. Determination of influenza virus proteins required for genome replication
23. Systematic peptide fragmentation of polyvinylidene difluoride (PVDF)-immobilized proteins prior to microsequencing
24. Purification and enzymatic properties of an RNA polymerase-RNA complex from influenza virus
25. Mutational analysis of the RNA-fork model of the influenza A virus vRNA promoter in vivo
26. Molecular dissection of influenza virus nucleoprotein: Deletion mapping of the RNA binding domain
27. RNA-dependent activation of primer RNA production by influenza virus polymerase: Different regions of the same protein subunit constitute the two required RNA-binding sites
28. Disruption of six Saccharomyces cerevisiae genes from chromosome IV and basic phenotypic analysis of deletion mutants
29. The polyadenylation signal of influenza virus RNA involves a stretch of uridines followed by the RNA duplex of the panhandle structure
30. Complete sequence and gene map of a human major histocompatibility complex
31. Identification of host factors that regulate the influenza virus RNA polymerase activity
32. Previously identified protein of uncertain function is karyopherin alpha and together with karyopherin beta docks import substrate at nuclear pore complexes
33. Localization of RNA polymerases on influenza viral ribonucleoproteins by immunogold labeling
34. Acidic molecular chaperones: Their involvement in viral genome replication and transcription
35. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3′ end formation of cellular pre-mRNAs
36. Affinity purification of antibodies from diazotized paper blots of heterogeneous protein samples
37. NPI-1, the human homolog of SRP-1, interacts with influenza virus nucleoprotein
38. Host-viral protein-protein interactions in influenza virus replication
39. Promoter analysis of influenza virus RNA polymerase
40. The HRIGRXXR region of the DEAD box RNA helicase eukaryotic translation initiation factor 4A is required for RNA binding and ATP hydrolysis
41. The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family
42. A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription
43. Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template
44. + mRNA in vitro
45. A new method for reconstituting influenza polymerase and RNA in vitro: A study of the promoter elements for cRNA and vRNA synthesis in vitro and viral rescue in vivo
46. Comparison of two reconstituted systems for in vitro transcription and replication of influenza virus
47. Influenza virus RNA replication in vitro: Synthesis of viral template RNAs and virion RNAs in the absence of an added primer
48. Regulation of influenza virus RNA polymerase activity by cellular and viral factors
49. A new cluster of genes within the human major histocompatibility complex
50. Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B
51. Mechanical devices of the spliceosome: Motors, clocks, springs, and things
52. In vitro synthesis of influenza viral RNA: Characterization of an isolated nuclear system that supports transcription of influenza viral RNA
53. The NPI-1/NPI-3 (karyopherin α) binding site on the influenza A virus nucleoprotein NP is a nonconventional nuclear localization signal
54. Interaction between influenza virus proteins and pine cone antitumor substance that inhibits the virus multiplication
55. Ns1-binding protein (NS1-BP): A novel human protein that interacts with the influenza A virus nonstructural Ns1 protein is relocalized in the nuclei of infected cells
56. Reconstitution of influenza virus RNA-nucleoprotein complexes structurally resembling native viral ribonucleoprotein cores