Origin of organic molecules and biomolecular homochirality

Cellular and Molecular Life Sciences

Volumn 58, Issue 1, 2001, Pages 44-60

  Podlech, J ^a  

^a UNIVERSITY OF STUTTGART   (Germany)

Author keywords

Amplification of chirality; Formation of organic compounds; Molecular evolution; Prebiotic chemistry

Indexed keywords

ORGANIC COMPOUND;

CHIRALITY; ENANTIOMER; GENE AMPLIFICATION; MOLECULAR EVOLUTION; PHOTOLYSIS; REACTION ANALYSIS; REVIEW; SYNTHESIS;

EID: 0035126061     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00000777     Document Type: Review

References (144)

1. Sur les relations qui peuvent exister entre la forme cristalline, la composition chimique et le sens de la polarisation rotatoire
2. Movements of the lower jaw of cattle during mastication
3. Chemical Evolution - Origin of the Elements, Molecules, and Living Systems
4. The Origin of Life A Review of Facts and Speculations
5. On the origin of metabolic pathways
6. Microfossils of the early archean apex chert: New evidence of the antiquity of life
7. Tracing the roots of the universal tree of life
8. Evidence for life on earth more than 3850 million years ago
9. Determining divergence times with a protein clock: Update and reevaluation
10. The origin of life - How long did it take
11. From panspermia to bioastronomy, the evolution of the hypothesis of universal life
12. Worlds in the Making: The Evolution of the Universe
13. The origin and early evolution of life on earth
14. The endogenous synthesis of organic compounds
15. Organic matter in meteorites: Molecular and isotopic analyses of the Murchison meteorite
16. Clues from the origin of the solar system: Meteorites
17. A production of amino acids under possible primitive earth conditions
18. Production of some organic compounds under possible primitive earth conditions
19. On the early chemical history of the earth and the origin of life
20. Prebiotic synthesis of hydrophobic and protein amino acids
21. Nonprotein amino acids from spark discharges and their comparision with the murchison meteorite amino acids
22. Synthesis of adenine from ammonium cyanide
23. Studies in prebiotic synthesis. III. Synthesis of pyrimidines from cyanoacetylene and cyanate
24. An efficient prebiotic synthesis of cytosine and uracil
25. Prebiotic ribose synthesis: A critical analysis
26. Chemie von α-Aminonitrilen. Aldomerisierung yon Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: Rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte
27. Are polyphosphates or phosphate esters prebiotic reagents
28. Early evolution of the atmosphere and ocean
29. Earth's early atmosphere
30. 2. I. Amino acids
31. 2. II. Hydrogen cyanide, formaldehyde and ammonia
32. Is extraterrestrial organic matter relevant to the origin of life on earth
33. Groundworks for an evolutionary biochemistry: The iron-sulphur world
34. Reactions depending on iron sulfide and linking geochemistry with biochemistry
35. Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions
36. Primordial amino acids by reductive amination of α-oxo acids in conjunction with the oxidative formation of pyrite
37. Origin of life in an iron-sulfur world
38. Peptides by activation of amino acids with CO on (Ni, Fe)S surfaces: Implications for the origin of life
39. Before enzymes and templates: Theory of surface metabolism
40. Clues from present-day biology: The thioester world
41. Aminoacyl thioester chemistry of class 1 aminoacyl-tRNA synthetases
42. Aminoacylation of coenzyme A and pantetheine by aminoacyl-tRNA synthetases: Possible link between noncoded and coded peptide synthesis
43. Did minerals perform prebiotic combinatorial chemistry?
44. Oligomerization of ribonucleotides on montmorillonite: Reaction of the 5′-phosphorimidazolide of adenosine
45. Montmorillonite catalysis of RNA oligomer formation in aqueous solution: A model for the prebiotic formation of RNA
46. Synthesis of long prebiotic oligomers on mineral surfaces
47. +-montmorillonite
48. Silica, alumina and clay catalyzed peptide bond formation: Enhanced efficiency of alumina catalyst
49. A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A
50. Extraterrestrial organic matter: A review
51. Chirality in interstellar dust and in comets: Life from dead stars
52. Prebiotic chiral molecules created in interstellar dust and preserved in comets, comet dust and meteorites: An exogenous source of life's origins
53. Tracking the organic refractory component from interstellar dust to comets
54. Life on Mars: Chemical arguments and clues from Martian meteorites
55. New insight into the source of biomolecular homochirality: An extraterrestrial origin for molecules of life?
56. Is amino-acid homochirality due to asymmetric phototysis in space?
57. Evidence for extraterrestrial amino-acids and hydrocarbons in the Murchison meteorite
58. Amino acids of the Murchison meteorite: Six carbon acyclic primary α-amino alkanoic acids
59. Amino acids of the Murchison meteorite. 11. Five carbon acyclic primary β-, γ-, and δ-amino alcanoic acids
60. Amino acids of the Murchison meteorite. III. Seven carbon acyclic primary α-amino alkanoic acids
61. Isotopic evidence for extraterrestrial non-racemic amino acids in the Murchison meteorite
62. Molecular and isotopic analyses of the hydroxy acids, dicarboxylic acids, and hydroxydicarboxylic acids of the Murchison meteorite
63. Alkyl phosphonic acids and sulfonic acids in the Murchison meteorite
64. Basic nitrogen-heterocyclic compounds in the Murchison meteorite
65. Carbon isotope composition of individual amino acids in the Murchison meteorite
66. Isotopic analyses of amino acids from the Murchison meteorite
67. Stable isotope analysis at the molecular level: A new approach for determining the origins of amino acids in the Murchison meteorite
68. Pre-biotic organic matter from comets and asteroids
69. Impact delivery and erosion of planetary oceans in the early inner solar system
70. Endogenous production, exogenous delivery and impact-shock synthesis of organic molecules: An inventory for the origins of life
71. Extraterrestrial amino acids and terrestrial life
72. Cometary delivery of organic molecules to the early earth
73. Origins of molecular chirality
74. β-Decay, Bremsstrahlen, and the origin of molecular chirality
75. Supernovae, neutron stars and biomolecular chirality
76. Origins of chiral homogeneity in nature
77. The origin and amplification of biomolecular chirality
78. Chirality, cosmochemistry and life
79. Chirality amplification - The accumulation principle revisited
80. Origins of biomolecular handedness
81. The electroweak origin of biomolecular handedness
82. Biomolecular handedness from Pasteur to parity non-conservation
83. Biomolecular homochirality
84. Absolute asymmetric synthesis: The origin, control, and amplification of chirality
85. Absolute asymmetric synthesis under physical fields: Facts and fictions
86. Question of parity conservation in weak interactions
87. Experimental test of parity conservation in beta decay
88. The parity violating energy differences between the enantiomers of α-amino acids
89. Computational studies of the electroweak origin of biomolecular handedness in natural sugars
90. Ab initio calculation of molecular energies including parity violating interactions
91. Structure and dynamics of chiral molecules
92. On the stabilization of natural 1.-α-amino acids and D-sugars via parity-violating effects
93. Optische aktivität und die paritätsverletzung im β-zerfall
94. Experimental evidences for parity violating energy differences between enantiomers
95. Primordial origins of chirality
96. Experimental attempts for the study of the origin of optical activity on earth
97. Asymmetric adsorption of alanine by quartz
98. Asymmetric adsorption of DL-alanine hydrochloride by quartz
99. True and false chirality and absolute asymmetric synthesis
100. Sur la symétrie dans les phénoménes physiques, symétrie d'un champ électrique et d'un champ magnétique
101. Darstellung optisch aktiver stoffe mit hilfe von licht
102. Preparation of chiral compounds with high optical purity by irradiation with circularly polarized light, a model reaction for the prebiotic generation of optical activity
103. Asymmetric photolysis of (RS)-leucine with circularly polarized ultraviolet light
104. Distribution and enantiomeric composition of amino acids in the Murchison meteorite
105. On the reported optical activity of amino acids in the Murchison meteorite
106. Reply to On the reported optical activity of amino acids in the Murchison meteorite
107. Enantiomeric excesses in meteoritic amino acids
108. Amino acid enantiomer excesses in meteorites: Origin and significance
109. Non-racemic amino acids in the Murray and Murchison meteorites
110. Circular polarization in star-formation regions: Implications for biomolecular homochirality
111. Comets and space missions
112. Introduction: Comets and the origin of life
113. On spontaneous asymmetric synthesis
114. Chiral symmetry breaking in sodium chlorate crystallization
115. Stirring rate as a critical parameter in chiral symmetry breaking crystallization
116. Secondary nucleation that leads to chiral symmetry breaking in stirred crystallization
117. Does life's handedness come from within?
118. Possible mechanisms for spontaneous production of enantiomeric excess
119. Method for obtaining an enantiomer containing less than 0.1% of its antipode: Determination of its maximum rotatory power
120. The two expressions of the Horeau principle, nth-order Horeau amplifications, and scales for the resulting very high enantiopurities
121. Polypeptides. IX. The kinetics of strong-base initiated polymerizations of amino acid-N-carboxanhydrides
122. Polypeptides. XVIII. A kinetic study of the polymerization of amino acid N-carboxyanhydrides initiated by strong bases
123. A model for the enantiomeric enrichment of polypeptides on the primitive earth
124. Experiments on the abiotic amplification of optical activity
125. Experiments on the amplification of optical activity
126. Pyranosyl-RNA: Chiroselective self-assembly of base sequences by ligative oligomerization of tetranucleotide-2′,3′-cyclophosphates (with a commentary concerning the origin of biomolecular homochirality)
127. The macromolecular route to chiral amplification
128. Majority rules in the copolymerization of mirror image isomers
129. A helical polymer with a cooperative response to chiral information
130. One-pot asymmetric autocatalytic reaction with remarkable amplification of enantiomeric excess
131. Amplification of a slight enantiomeric imbalance in molecules based on asymmetric autocatalysis: The first correlation between high enantiomeric enrichment in a chiral molecule and circularly polarized light
132. Asymmetric autocatalysis and biomolecular chirality
133. Enantioselective automultiplication of chiral molecules by asymmetric autoatalysis
134. d- and -Quartz-promoted highly enantioselective synthesis of a chiral organic compound
135. Asymmetric synthesis of an organic compound with high enantiomeric excess induced by inorganic ionic sodium chlorate
136. Basic terminology of stereochemistry (IU-PAC recommendations 1996)