Stimulation of human peripheral blood mononuclear cells with live mycobacterium bovis BCG activates cytolytic CD8+ T cells in vitro

Immunology

Volumn 87, Issue 3, 1996, Pages 339-342

  Turner, J ^a   Dockrell, H M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BCG VACCINE; CD8 ANTIGEN; HLA DR ANTIGEN; INTERLEUKIN 2 RECEPTOR; MYCOBACTERIUM ANTIGEN; TRANSFERRIN RECEPTOR;

ADULT; ARTICLE; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; MYCOBACTERIUM BOVIS; MYCOBACTERIUM TUBERCULOSIS; NORMAL HUMAN; PRIORITY JOURNAL; VACCINATION;

EID: 0029933481     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1996.512590.x     Document Type: Article

References (10)

1. PFEIFER J.D., WICK M.J., ROBERTS R.L., FINDLAY K., NORMARK S.J. & HARDING C.V. (1993) Phagocytic processing of bacterial antigens for class I MHC presentation to T cells. Nature 361, 359.
2. KOVACSCOVICS-BANKOWSKI M., CLARK K., BENECERRAF B. & ROCK K.L. (1993) Efficient major histocompatibility complex class 1 presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci USA 90, 4942.
3. MCDONOUGH K.A., KRESS Y. & BLOOM B.R. (1993) Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect Immun 61, 2763.
4. CROWLF A.J., DAHL R., ROSS E. & MAY M.H. (1991) Evidence that vesicles containing living, virulent Mycobacterium tuberculosis or Mycobacterium avium in cultured human macrophages are not acidic. Infect Immun 59, 1823.
5. CLEMENS D.L. & HORWITZ M.A. (1995) Characterization of the Mycobacterium tuberculosis phagosome and evidence that phagosomal maturation is inhibited. J Exp Med 181, 257.
6. FLYNN J., GOLDSTEIN M.M., TRIEBOLD K.J. & KOLLER B. (1992) Major histocompatibility complex class I-restricted T cells are required for resistance to Mycobacterium tuberculosis infection. Proc Natl Acad Sci USA 89, 12013.
7. KUMARARATNE D.S., PITHIE A.S., DRYSDALE P. et al. (1990) Specific lysis of mycobacterial antigen-bearing macrophages by class II MHC-restricted polyclonal T cell lines in healthy donors or patients with tuberculosis. Clin Exp Immunol 80, 314.
8. STURGILL-KOSZYCKI S., SCHLESINGER P.H., CHAKRABORTY P. et al. (1994) Lack of acidification in Mycobacterium phagosomes produced by exclusion of the vesicular proton-ATPase. Science 263, 678.
9. DUUGELAT S., LADEL C.H. & KAUFMANN S.H.E. (1995) Influence of mouse strain and vaccine viability on T-cell responses induced by Mycobacterium bovis bacillus Calmette-Guérin. Infect Immun 63, 2033.
10. ORME I.M. (1988) Induction of nonspecific acquired resistance and delayed-type hypersensitivity, but not specific acquired resistance, in mice inoculated with killed mycobacterial vaccines. Infect Immun 56, 3310.