The effect of lipid composition on receptor-mediated in vivo gene transfection using mannosylated cationic liposomes in mice

S.T.P. Pharma Sciences

Volumn 11, Issue 1, 2001, Pages 117-120

  Kawakami, S ^a   Sato, A ^a   Yamada, M ^a   Yamashita, F ^a   Hashida, M ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Cationic liposomes; Gene delivery; Gene therapy; Mannosylated liposomes

Indexed keywords

CATION; CHOLESTEN 5 YLOXY N [4 [(1 IMINO 2 BETA DEXTRO THIOMANNOSYLETHYL)AMINO]BUTYL]FORMAMIDE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; FORMAMIDE DERIVATIVE; LUCIFERASE; MANNOSE RECEPTOR; N [1 (2,3 DIOLEYLOXY)PROPYL] N,N,N TRIMETHYLAMMONIUM CHLORIDE; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ADMINISTRATION; ENDOCYTOSIS; GENE EXPRESSION; GENE TARGETING; GENE THERAPY; GENETIC TRANSFECTION; INTRAPORTAL DRUG ADMINISTRATION; LIPID COMPOSITION; LIVER; LUNG; MOUSE; NONHUMAN;

EID: 0035125644     PISSN: 11571489     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Systemic gene therapy: Biodistribution and long-term expression of a transgene in mice
2. In vitro and in viva gene delivery mediated by a synthetic polycationic amino polymer
3. Characterization of cationic liposome-mediated gene transfer in viva by intravenous administration
4. Stabilization of cationic liposome-plasmid DNA complexes by polyamines and poly(ethylene glycol)-phospholipid conjugates for efficient in vivo gene delivery
5. Improved DNA: Liposome complexes for increased systemic delivery and gene expression
6. A novel series of amphiphilic imidazolium compounds for in vitro and in viva gene delivery
7. Factors influencing the efficiency of cationic liposome-mediated intravenous gene delivery
8. Non-viral vectors for in viva gene delivery: Physicochemical and pharmacokinetic considerations
9. Mannose receptor-mediated gene transfer into macrophages using novel mannosylated cationic liposomes
10. 2-Imino-2-methoxyethyl-1-thioglycosides: New reagents for attaching sugars to proteins
11. Advantages of firefly luciferase as a reporter gene: Application to the interleukin-2 gene promotor
12. Lowry determination of protein in the presence of Triton X- 100
13. Asialoglycoprotein receptor-mediated gene transfer using novel galactosylated cationic liposomes
14. In viva gene delivery to the liver using novel galactosylated cationic liposomes
15. The fate of plasmid DNA after intravenous injection in mice: Involvement of scavenger receptors in its hepatic uptake
16. In viva gene transfer by intravenous administration of stable cationic lipid/DNA complex
17. Factors controlling the efficiency of Cationic lipid-mediated transfection in vivo via intravenous administration
18. Biodistribution and gene expression of lipid/ plasmid complexes after systemic administration
19. Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: Implications for intravenous lipofection
20. Lipoplex-mediated gene delivery to the lung occurs within 60 minutes of intravenous administration