Protective effect of metronidazole on uncoupling mitochondrial oxidative phosphorylation induced by NSAID: A new mechanism

Gut

Volumn 48, Issue 2, 2001, Pages 163-167

  Leite, A Z A ^a   Sipahi, A M ^a   Damiao A O M C ^a   Coelho, A M M ^a   Garcez, A T ^a,b   Machado, M C C ^a   Buchpiguel, C A ^a,b   Lopasso, F P ^a   Lordello, M L ^a   Agostinho, C L O ^a   Laudanna, A A ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b General Clinics Hospital of the USP Medical School   (United Kingdom)

Author keywords

Enteropathy; Indomethacin; Intestinal permeability; Metronidazole; Non steroidal anti inflammatory drugs; Rats; Uncoupling agents

Indexed keywords

INDOMETACIN; METRONIDAZOLE; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENTEROPATHY; HISTOPATHOLOGY; INTESTINE MUCOSA PERMEABILITY; MALE; MITOCHONDRIAL RESPIRATION; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG INTERACTIONS; INDOMETHACIN; INTESTINAL MUCOSA; MALE; METRONIDAZOLE; MITOCHONDRIA; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PERMEABILITY; RATS; RATS, WISTAR; REGRESSION ANALYSIS; STATISTICS, NONPARAMETRIC; UNCOUPLING AGENTS;

EID: 0035125327     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.48.2.163     Document Type: Article

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