The role of desensitisation in decay time of miniature endplate currents in frogs Rana ridibunda and Rana temporaria

Neuroscience Research

Volumn 39, Issue 3, 2001, Pages 287-292

  Giniatullin, R A ^a   Talantova, M V ^a   Vyskocil F ^b  

^a CHARLES UNIVERSITY   (Czech Republic)

^b INSTITUTE OF PHYSIOLOGY   (Czech Republic)

Author keywords

Acetylcholine receptor; Desensitisation; Frog; Miniature endplate potential; Quantal release

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINERGIC RECEPTOR; IONOTROPIC RECEPTOR; NEOSTIGMINE; POSTSYNAPTIC RECEPTOR; PROADIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FROG; MINIATURE ENDPLATE POTENTIAL; NERVE CELL PLASTICITY; NEUROMUSCULAR SYNAPSE; NONHUMAN; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DOWN REGULATION;

ANIMALS; BUNGAROTOXINS; CHOLINESTERASE INHIBITORS; ENZYME INHIBITORS; MOTOR ENDPLATE; MUSCLE, SKELETAL; NEOSTIGMINE; NEURONAL PLASTICITY; PROADIFEN; RANA RIDIBUNDA; RANA TEMPORARIA; RECEPTORS, CHOLINERGIC; SPECIES SPECIFICITY;

EID: 0035117574     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(00)00225-X     Document Type: Article

References (34)

1. The 'desensitizing' effect of acetylcholine on the mammalian motor end-plate
2. Voltage-clamp analysis of acetylcholine induced end-plate current fluctuation at frog neuromuscular junction
3. + ion fluxes
4. Nature of the postsynaptic action of crotoxin at guinea-pig diaphragm end-plates
5. Permeability control and desensitization by nicotinic acetylcholine receptors
6. The synthesis and release of acetylcholine in normal and denervated rat diaphragms during incubation in vitro
7. Interaction between nerve-released acetylcholine and bath-applied agonists at the frog end-plate
8. Development of desensitization during repetitive end-plate activity and single end-plate currents in frog muscle
9. The effect of nonquantal acetylcholine release on quantal miniature currents at mouse diaphragm
10. A correlation between quantum content and decay time of end-plate currents in neuromuscular junction with intact acetylcholinestearse
11. Desensitization shortens the high-quantal-content endplate current time course in frog muscle with intact cholinesterase
12. Potent acetylcholinesterase inhibitors: design, synthesis and structure-activity relationships of alkylene linked bis-galanthamine and galanthamine-galanthaminium salts
13. Fast kinetic studies on the allosteric interactions between acetylcholine receptor and local anesthetic binding sites
14. The impact of receptor desensitization on fast synaptic transmission
15. A study of 'desensitization'produced by acetylcholine at the motor end-plate
16. The binding of acetylcholine to receptors and its removal from the synaptic cleft
17. Transmitter leakage from motor nerve endings
18. The nature and origin of calcium-insensitive miniature end-plate potentials at rodent neuromuscular junctions
19. Mechanism of action of diethylaminoethyl ether of diphenylpropylacetic acid SKF-525A on the neuromuscular synapse
20. Dependence of acetylcholine desensitization on the membrane potential of frog muscle fibre and on the ionic changes in the medium
21. The effect of temperature on desensitization kinetics at the post-synaptic membrane of the frog muscle fibre
22. Effect of the desensitization-potentiating agent SKF-525A on frog end-plate currents
23. End-plate currents evoked by paired stimuli in frog muscle fibres
24. The factors determining the time course of the miniature end-plate currents
25. Changes in the time course of miniature end plate currents induced by bath applied acetylcholine
26. A study of desensitization of acetylcholine receptors using nerve-released transmitter in the frog
27. Effect of nitric oxide and NO synthase inhibition on nonquantal acetylcholine release in the rat diaphragm
28. Relation between subsynaptic receptor blockage and responses to quantal transmitter at the mouse neuromuscular junction
29. Differential expression of receptor subunits: a mechanism underlying developmental changes in synaptic transmission
30. Changes in total and quantal release of acetylcholine in the mouse diaphragm during activation and inhibition of membrane ATPase
31. The desensitization of postjunctional muscle membrane after intracellular application of membrane stabilizers and snake venom polypeptides
32. Recovery of sensitivity to acetylcholine following desensitization in muscles of different vertebrate species
33. An analysis of the mechanisms underlying the non-quantal release of acetylcholine at the mouse neuromuscular junction
34. Quantal and non-quantal ACh release at developing Xenopus neuromuscular junctions in culture