Tissue-specific alterations in the 6-hydroxylation of chlorzoxazone following traumatic brain injury in the rat

Drug Metabolism and Disposition

Volumn 29, Issue 3, 2001, Pages 296-298

  Poloyac, S M ^a   Perez, A ^a   Scheff, S ^a   Blouin, R A ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 METHYLPYRAZOLE; 6 HYDROXYCHLORZOXAZONE; CHLORZOXAZONE; CYTOCHROME P450 2E1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; BRAIN MICROSOME; CONTROLLED STUDY; DRUG HYDROXYLATION; ENZYME ACTIVITY; KIDNEY MICROSOME; LIVER LEVEL; LIVER METABOLISM; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BRAIN; BRAIN INJURIES; CHLORZOXAZONE; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; HYDROXYLATION; KIDNEY; LIVER; MALE; MICROSOMES; ORGAN SPECIFICITY; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0035112019     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

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14. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 in the rat central nervous system
15. Head injury and cytochrome P450 enzymes