SJL and NOD macrophages are uniquely characterized by genetically programmed, elevated expression of the IL-12(p40) gene, suggesting a conserved pathway for the induction of organ-specific autoimmunity

Journal of Leukocyte Biology

Volumn 69, Issue 3, 2001, Pages 440-448

  Alleva, David G ^a   Johnson, Eric B ^a   Wilson, Jerry ^b   Beller, David I ^c   Conlon, Paul J ^a  

^a NEUROCRINE BIOSCIENCES INC   (United States)

^b BD BIOSCIENCES   (United States)

^c BOSTON UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antigen presenting cell; Cytokines; Diabetes; EAE; Multiple sclerosis

Indexed keywords

CANCER GROWTH FACTOR; GENE PRODUCT; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; PROTEIN P40; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOPHYSIOLOGY; PERITONEUM MACROPHAGE; PHENOTYPE; PRIORITY JOURNAL; STRAIN DIFFERENCE; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ANIMALS; ANTIGEN-PRESENTING CELLS; AUTOIMMUNITY; CD40 LIGAND; DIMERIZATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; INTERFERON TYPE II; INTERLEUKIN-12; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED NOD; ORGAN SPECIFICITY;

ANIMALIA;

EID: 0035106949     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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