Developmental mosaicism may explain spontaneous reappearance of the AxinFu mutation in mice

Genesis

Volumn 29, Issue 2, 2001, Pages 49-54

  Ruvinsky, Anatoly ^a   Flood, Warren D ^a   Costantini, Frank ^b  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

Axin mutation; Developmental mosaicism; Gene conversion; IAP insertion; Reversion

Indexed keywords

AGAROSE; MICROSATELLITE DNA; POLYACRYLAMIDE;

ALLELE; ARTICLE; CHROMOSOME ANALYSIS; CHROMOSOME SEGREGATION; GENE AMPLIFICATION; GENE CONVERSION; GENE INSERTION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HAPLOTYPE; HETEROZYGOSITY; INTRON; MOLECULAR CLONING; MOSAICISM; PENETRANCE; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGENY;

ANIMALS; CLONING, MOLECULAR; ELECTROPHORESIS, AGAR GEL; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; GENE CONVERSION; GENES, INTRACISTERNAL A-PARTICLE; GENOTYPE; MALE; MICE; MICE, TRANSGENIC; MICROSATELLITE REPEATS; MOSAICISM; MUTATION; PEDIGREE; PHENOTYPE; POLYMERASE CHAIN REACTION; PROTEINS; REPRESSOR PROTEINS; TAIL;

EID: 0035105768     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1526-968X(200102)29:2<49::AID-GENE1004>3.0.CO;2-2     Document Type: Article

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13. Fu mutation in mice is associated with widespread rearrangements in the proximal region of Chromosome 17
14. Evidence for cyclophosphamide-induced gene conversion and mutation in mouse germ cells
15. De novo facioscapulohumeral muscular dystrophy: Frequent somatic mosaicism, sex-dependent phenotype, and the role of mitotic transchromosomal repeat interaction between chromosomes 4 and 10
16. Two dominant mutations in the mouse fused gene are the result of transposon insertions
17. The mouse Fused locus encodes Axin. An inhibitor of the Wnt signaling pathway that regulates embryonic axis formation