Combining G-CSF with a blockade of adhesion strongly improves the reconstitutive capacity of mobilized hematopoietic progenitor cells

Experimental Hematology

Volumn 29, Issue 3, 2001, Pages 380-390

  Christ, Oliver ^a   Kronenwett, Ralf ^a   Haas, Rainer ^a   Zöller, Margot ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BETA1 INTEGRIN; GRANULOCYTE COLONY STIMULATING FACTOR; HERMES ANTIGEN;

ANIMAL CELL; ARTICLE; BIOLOGICAL THERAPY; BONE MARROW; CELL ADHESION; CELL GROWTH; COLONY FORMING UNIT; CONTROLLED STUDY; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELL; IMMUNOCOMPETENCE; MOBILIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTE; SPLEEN CELL;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD44; BONE MARROW TRANSPLANTATION; CELL ADHESION; COLONY-FORMING UNITS ASSAY; DRUG SYNERGISM; GRAFT SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; IMMUNOCOMPETENCE; INTEGRIN ALPHA4BETA1; INTEGRINS; MICE; MICE, INBRED BALB C; ORGAN SPECIFICITY; RADIATION CHIMERA; RECEPTORS, LYMPHOCYTE HOMING; SPLEEN;

EID: 0035102513     PISSN: 0301472X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0301-472X(00)00674-3     Document Type: Article

References (48)

1. Peripheral blood stem cell mobilization for hematopoietic support of radioimmunotherapy in patients with breast carcinoma
2. Alloantigen presenting capacity, T cell alloreactivity and NK function of G-CSF-mobilized peripheral blood cells
3. Peripheral blood stem cell mobilization for high-dose chemotherapy
4. The role of granulocyte colony stimulating factor in mobilization and transplantation of peripheral blood progenitor and stem cells
5. Use of G-CSF to mobilize PBSC in normal healthy donors-an international survey
6. + cells from bone marrow to peripheral blood is selective in steady-state hematopoiesis and during G-CSF administration
7. Single leukapheresis products collected from healthy donors after the administration of granulocyte colony-stimulating factor contain ten-fold higher numbers of long-term reconstituting hematopoietic progenitor cells than conventional bone marrow allografts
8. Peripheralization of hematopoietic progenitors in primates treated with anti-VLA4 integrin
9. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells
10. + hematopoietic progenitor cells; comparison of cytokine mobilized blood stem cells with normal bone marrow and peripheral blood
11. Homing and trafficking of hemopoietic progenitor cells
12. Anti-VLA4/VCAM-1-induced mobilization requires cooperative signaling through the kit/mkit ligand pathway
13. Involvement of CD44 exon v10 in B cell maturation
14. CD44v10 in hematopoiesis and stem cell mobilization
15. Antibodies to VLA4 integrin mobilize long-term repopulating cells and augment cytokine-induced mobilization in primates and mice
16. Expression and function of integrins on hematopoietic progenitor cells
17. VLA4-mediated interactions between normal human hematopoietic progenitors and stromal elements
18. CD44 isoforms in normal and leukemic hematopoiesis
19. Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans
20. Cell adhesion in the stromal regulation of haemopoiesis
21. Hematopoietic progenitor cell expression of the H-CAM (CD44) homing-associated adhesion molecule
22. Effects of anti-CD44 monoclonal antibody on adhesion of erythroid leukemic cells (ELM-l-1) to hematopoietic supportive cells (MS-5); CD44, but not hyaluronate-mediated, cell-cell adhesion
23. Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells
24. The ontogeny of human lymphocyte recirculation; high endothelial cell antigen (HECA-452) and CD44 homing receptor expression in the development of the immune system
25. Characterization of CD44 antigen during lymphoid ontogeny
26. Expression of CD44 molecules and CD44 ligands during human thymic fetal development; expression of CD44 isoforms is developmentally regulated
27. + human thymic precursors can be traced by the differential expression of CD44
28. CD44 is the principal cell surface receptor for hyaluronate
29. Production of heparan sulphate proteoglycans by human bone marrow stromal cells
30. Hyaluronic acid regulates the function and distribution of sulfated glycosaminoglycans in bone marrow stromal cultures
31. Requirement for CD44 in stem cell proliferation and homing
32. Adhesion of committed human hematopoietic progenitors to synthetic peptides from the C-terminal heparin-binding domain of fibronectin; cooperation between the integrin α 4 β 1 and the CD44 adhesion receptor
33. Adhesive interactions in hemopoiesis
34. CD44 and other cell interaction molecules contributing to B lymphopoiesis
35. Cloning of murine and rat vascular cell adhesion molecule-1
36. Interleukin-3 and interleukin-7 are alternative growth factors for the same B-cell precursors in the mouse
37. CD44 regulates hematopoietic progenitor distribution, granuloma formation, and tumorigenicity
38. Costimulatory function of CD44 in T cell proliferation and apoptosis
39. Identification of a costimulatory molecule rapidly induced by CD40L as CD44H
40. CD44 selectively associates with active Src family protein tyrosine kinases Lck and Fyn in glycoshingolipid-rich plasma membrane domains of human peripheral blood lymphocytes
41. Requirements for signal delivery through CD44; analysis using CD44-Fas chimeric proteins
42. Ligation of CD44 adhesion molecules reverses blockade of differentiation in human acute myeloid leukemia
43. Activation of β1 integrins on CML progenitors reveals cooperation between β1 integrins and CD44 in the regulation of adhesion and proliferation
44. + cells predict a rapid platelet recovery after peripheral blood stem cell transplantation
45. CD44 and its interaction with extracellular matrix
46. + cells during mobilization with G-CSF
47. Granulocyte colony-stimulating factor (G-CSF) transiently suppresses mitogen-stimulated T-cell proliferative response