Modulation of VLA-4 and L-selectin expression on normal CD34+ cells during mobilization with G-CSF

Bone Marrow Transplantation

Volumn 23, Issue 1, 1999, Pages 1-8

  Bellucci, R ^b   De Propris, M S ^c   Buccisano, F ^a   Lisci, A ^c   Leone, G ^c   Tabilio, A ^c   De Fabritiis, P ^c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Institute of Haematology   (Italy)

^c NONE

Author keywords

Adhesion molecules; CD34+ cells; G CSF; Normal donors

Indexed keywords

BETA1 INTEGRIN; CD18 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD38 ANTIGEN; CELL ADHESION MOLECULE; HLA DR ANTIGEN; L SELECTIN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MICROSOMAL AMINOPEPTIDASE; MONOCLONAL ANTIBODY; PADGEM PROTEIN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; STEM CELL FACTOR;

ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CELL ADHESION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LEUKOCYTE COUNT; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEADY STATE; STROMA CELL; SUBCUTANEOUS DRUG ADMINISTRATION;

EID: 0032968615     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1701522     Document Type: Article

References (25)

1. Duhrsen U, Villeval J-L, Boyd J et al. Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients. Blood 1988; 72: 2074-2081.
2. Socinski MA, Cannistra SA, Elias A et al. Granulocyte-macrophage colony-stimulating factor expands the circulating haemopoietic progenitor cell compartment in man. Lancet 1988; 1: 1194-1198.
3. Long MV, Briddell R, Walter AW et al. Human hematopoietic stem cell adherence to cytokines and matrix molecules. J Clin Invest 1992; 90: 251-256.
4. Juneja HS, Schmalsteig FC, Lee S, Chen J. Vascular cell adhesion molecule-1 and VLA-4 are obligatory adhesion proteins in the heterotypic adherence between human leukemia/lymphoma cells and marrow stromal cells. Exp Hematol 1993; 21: 444-450.
5. Miyake K, Weissman IL, Greenberger JS, Kincade PW. Evidence for a role of the integrin VLA-4 in lympho-hemopoiesis. J Exp Med 1991; 173: 599-607.
6. hi stem cells to bone marrow stroma. J Clin Invest 1992; 90: 358-367.
7. Saeland S, Duvert V, Caux C et al. Distribution of surface-membrane molecules on bone marrow and cord blood CD34+ hematopoietic cells. Exp Hematol 1992; 20: 24-33.
8. Lawrence MB, Springer TA. Leukocytes roll on a selectin at physiologic flow rates: distinction from and prerequisite for adhesion through integrins. Cell 1991; 65: 859-873.
9. Springer TA. Adhesion receptors of the immune system. Nature 1990; 346: 425-434.
10. Stoolman LM. Adhesion molecules controlling lymphocyte migration. Cell 1989; 56: 907-910.
11. Lund Johansen F, Terstappen LW. Differential surface expression of cell adhesion molecules during granulocyte maturation. J Leuk Biol 1993; 54: 47-55.
12. Mohle R, Haas R, Hunstein W. Expression of adhesion molecules and c-Kit on CD34+ cells: comparison of cytokine-mobilized blood stem cells with normal bone marrow and peripheral blood. J Hematother 1993; 2: 483-489.
13. Mohle R, Murea S, Kirsch M, Haas R. Differential expression of L-selectin, VLA-4, and LFA-1 on CD34+ progenitor cells from bone marrow and peripheral blood during G-CSF enhanced recovery. Exp Hematol 1995; 23: 1535-1542.
14. Gunji Y, Nakamura M, Hagiwara T et al. Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1-cells are more primitive then CD34+ LFA-1+ cells. Blood 1992; 80: 429-436.
15. Torensma R, Raymakers RAP, van Kooyk Y, Figdor CG. Induction of LFA-1 on pluripotent CD34+ bone marrow cells does not affect lineage commitment. Blood 1996; 87: 4120-4128.
16. Siena S, Bregni M, Brando B et al. Flow-cytometry for clinical estimation of circulating hematopoietic progenitors for autologous transplantation in cancer patients. Blood 1991; 77: 400-409.
17. Fauser AA, Messner HA. Granuloerythropoietic colonies in human bone marrow, peripheral blood and cord blood. Blood 1978; 52: 1243-1248.
18. Prosper F, Stronceck D, Verfaille CM. Phenotypic and functional characterization of long-term culture-initiating cells present in peripheral blood progenitor collections of normal donors treated with granulocyte colony-stimulating factor. Blood 1996; 88: 2033-2042.
19. To LB, Haylock DN, Dowse T et al. A comparative study of the phenotype and proliferative capacity of peripheral blood PB) CD34+ cells mobilized by four different protocols and those of steady-phase PB and bone marrow CD34+ cells. Blood 1994; 84: 2930-2939.
20. d mice. Leukemia 1991; 5: 75-77.
21. Humeau L, Bardin F, Maroc C et al. Phenotypic, molecular, and functional characterization of human peripheral blood CD34+/THY-1+ cells. Blood 1996; 87: 949-955.
22. Haas R, Mohle R, Pforsich M et al. Blood-derived autograft collected during granulocyte-colony stimulating factor-enhanced recovery are enriched with early Thy-1+ hematopoietic progenitor cells. Blood 1995; 85: 1936-1943.
23. Craig W, Kay R, Cutler RL, Lansdorp PM. Expression of Thy-1 on human hematopoietic progenitor cells. J Exp Med 1993; 177: 1331-1342.
24. Williams DA, Rios M, Stephens C, Patel VP. Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature 1991; 352: 438-441.
25. Papayannopoulou T, Nakamoto B. Peripheralization of hemopoietic progenitors in primates treated with anti-VLA-4 integrin. Proc Natl Acad Sci USA 1993; 90: 9374-9378.